公开(公告)号：US09763777B2

公开(公告)日：2017-09-19

申请号：US14131710

申请日：2012-07-11

申请人： Marcus Atlas ,  William Brett Robertson ,  Robert Jeffrey Marano ,  Sharon Leanne Redmond ,  Peter Luke Santa Maria ,  Brett Levin ,  Bing Mei Teh

发明人： Marcus Atlas ,  William Brett Robertson ,  Robert Jeffrey Marano ,  Sharon Leanne Redmond ,  Peter Luke Santa Maria ,  Brett Levin ,  Bing Mei Teh

IPC分类号： A61F2/18 ,  A61L27/22 ,  A61L27/24 ,  A61L27/38 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56 ,  A61B17/00

CPC分类号： A61F2/18 ,  A61B2017/00787 ,  A61F2002/183 ,  A61L27/227 ,  A61L27/24 ,  A61L27/38 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/236 ,  A61L2300/252 ,  A61L2300/414 ,  A61L2300/426 ,  A61L2430/14

摘要： A device for use in the repair of an ear drum in a subject in need of such treatment, said device: having a tensile strength Youngs Modulus between approximately 12.5 and 40 MPa; comprising one or more membrane layers, wherein at least one membrane layer comprises a plurality of pores; and wherein the device can support proliferation, migration and/or adhesion of cells selected from the group comprising at least any one or more of: keratinocytes, fibroblasts, vascular cells, mucosal epithelial cells, and stem cells.

公开(公告)号：US20140303727A1

公开(公告)日：2014-10-09

申请号：US14131710

申请日：2012-07-11

申请人： Marcus Atlas ,  William Brett Robertson ,  Robert Jeffrey Marano ,  Sharon Leanne Redmond ,  Peter Luke Santa Maria ,  Brett Levin ,  Bing Mei Teh

发明人： Marcus Atlas ,  William Brett Robertson ,  Robert Jeffrey Marano ,  Sharon Leanne Redmond ,  Peter Luke Santa Maria ,  Brett Levin ,  Bing Mei Teh

IPC分类号： A61F2/18

CPC分类号： A61F2/18 ,  A61B2017/00787 ,  A61F2002/183 ,  A61L27/227 ,  A61L27/24 ,  A61L27/38 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/236 ,  A61L2300/252 ,  A61L2300/414 ,  A61L2300/426 ,  A61L2430/14

摘要： A device for use in the repair of an ear drum in a subject in need of such treatment, said device: having a tensile strength Youngs Modulus between approximately 12.5 and 40 MPa; comprising one or more membrane layers, wherein at least one membrane layer comprises a plurality of pores; and wherein the device can support proliferation, migration and/or adhesion of cells selected from the group comprising at least any one or more of: keratinocytes, fibroblasts, vascular cells, mucosal epithelial cells, and stem cells.

摘要翻译： 一种用于在需要这种处理的受试者中修复耳鼓的装置，所述装置具有约12.5至40MPa之间的拉伸强度杨氏模量; 包括一个或多个膜层，其中至少一个膜层包含多个孔; 并且其中所述装置可以支持选自包括角化细胞，成纤维细胞，血管细胞，粘膜上皮细胞和干细胞中的至少任何一个或多个的组的细胞的增殖，迁移和/或粘附。