Passive Middle Ear Prosthesis
    3.
    发明申请

    公开(公告)号:US20190201189A1

    公开(公告)日:2019-07-04

    申请号:US16327883

    申请日:2017-09-12

    Abstract: A middle ear prosthesis is made of a stiff deformable material and includes a planar head end with a central portion having a central diameter. The head end is adapted for engagement with a tympanic membrane from the middle ear of an implanted patient. An opposing pair of U-shaped stapes engagement legs bend down from the central portion so that an end distance between ends of the engagement legs is less than the central diameter. The engagement legs are adapted for adjustable length engagement with the stapes in the middle ear of the implanted patient. The head end and the engagement legs are adapted to transmit vibrations from the tympanic membrane to the stapes for perception as sound by the implanted patient.

    Percutaneous bone conduction implant
    6.
    发明授权
    Percutaneous bone conduction implant 有权
    经皮骨传导植入

    公开(公告)号:US08787607B2

    公开(公告)日:2014-07-22

    申请号:US12732155

    申请日:2010-03-25

    Inventor: Marcus Andersson

    Abstract: One embodiment relates to a percutaneous bone conduction implant. The implant includes a fixture configured to be anchored in the recipient's skull, and a skin-penetrating abutment configured to interface with the fixture and to permit the abutment to be removably attached to the fixture to form a fixture-abutment assembly. In an embodiment, at least one anti-microbial surface forms one or more surfaces of the formed fixture-abutment assembly located in an interior of the formed fixture-abutment assembly when the fixture is removably attached to the abutment with an abutment screw. The interior is substantially isolated from a surrounding environment of the fixture-abutment assembly.

    Abstract translation: 一个实施例涉及经皮骨传导植入物。 植入物包括被配置为锚定在接收者的颅骨中的固定器,以及皮肤穿透的邻接构造成与固定装置相接合并且允许邻接件可移除地附接到固定装置以形成夹具 - 邻接组件。 在一个实施例中,当固定装置可拆卸地连接到具有基台螺钉的基台时,至少一个抗微生物表面形成位于所形成的固定件 - 邻接组件的内部中的所形成的固定件 - 邻接组件的一个或多个表面。 内部基本上与固定装置 - 邻接组件的周围环境隔离。

    DRUG DELIVERY USING A SACRIFICIAL HOST
    7.
    发明申请
    DRUG DELIVERY USING A SACRIFICIAL HOST 有权
    药物使用真正的主机运送

    公开(公告)号:US20140188033A1

    公开(公告)日:2014-07-03

    申请号:US14064354

    申请日:2013-10-28

    Abstract: Implantable drug-doped component, e.g., a cochlear implant, including host material, a host-embedded drug, a sacrificial material integrated with the host. Sacrificial material facilitates release of drug from the component. Sacrificial material facilitates release through creation of voids in the host upon dissolution of sacrificial material upon contact with a solvent, e.g., perilymph fluid upon implant. Host can be polysiloxane, or silicone rubber. Drug can be anti-inflammatory, growth factor, antibody, anti-oxidant, antibiotic, corticosteroid. Sacrificial material can be: glucose monomer, sugar, cyclodextrin, dissolvable or resorbable at implant site, a salt, bioresorbable material, hyaluronic acid, polyurethane, polyester, polyamide, polyvinyl alcohol, polyacrylic acid. Sacrificial material can be the host, and can facilitate release of drug through changing a property of sacrificial material, e.g., by exposing component to ethanol wash. For a cochlear implant, drug doped material can be applied to a non-stimulating surface of the electrode array, and can be a physical feature of stimulating medical device, e.g., soft tip, ridge, spine. For a cochlear implant the drug-doped material can excluded from the basal side of the most basal electrode contact.

    Abstract translation: 可植入药物掺杂组分,例如耳蜗植入物,包括宿主材料,宿主植入药物,与宿主整合的牺牲材料。 牺牲物质有助于药物从组分中的释放。 牺牲材料通过在与溶剂(例如植入物上的外淋巴液)接触时溶解牺牲材料时在主体中产生空隙来促进释放。 主体可以是聚硅氧烷或硅橡胶。 药物可以是抗炎,生长因子,抗体,抗氧化剂,抗生素,皮质类固醇。 牺牲材料可以是:葡萄糖单体,糖,环糊精,在植入部位可溶或可吸收,盐,生物可再吸收材料,透明质酸,聚氨酯,聚酯,聚酰胺,聚乙烯醇,聚丙烯酸。 牺牲材料可以是宿主,并且可以通过改变牺牲材料的性质来促进药物的释放,例如通过将组分暴露于乙醇洗涤液中。 对于耳蜗植入物,药物掺杂材料可以施加到电极阵列的非刺激表面,并且可以是刺激医疗装置的物理特征,例如软尖端,脊脊,脊柱。 对于耳蜗植入物,药物掺杂材料可以从最基底的电极接触的基底侧排除。

    Techniques For Increasing The Acoustic Impedance Of The Cochlea's Round Window Membrane
    8.
    发明申请
    Techniques For Increasing The Acoustic Impedance Of The Cochlea's Round Window Membrane 审中-公开
    用于增加耳蜗圆形窗膜阻抗的技术

    公开(公告)号:US20140172099A1

    公开(公告)日:2014-06-19

    申请号:US13714216

    申请日:2012-12-13

    Abstract: A method for increasing the acoustic impedance of the round window membrane of the cochlea in a human patient includes surgically opening access to the round window membrane and placing a packing layer over the round window membrane. Optionally a layer of collagen graft may be obtained from the patient and placed between the round window membrane and the packing layer. Optionally the packing layer may be enclosed within the collagen graft. Optionally bone paté may be obtained from the patient and used to form at least a portion of the packing layer. Optionally a silastic buttress may be placed under compression between the packing layer and the bone of sinus tympani of the patient.

    Abstract translation: 一种用于增加人类患者耳蜗的圆形窗膜的声阻抗的方法包括手术打开进入圆窗膜并将包装层放置在圆窗膜上。 任选地,可以从患者获得胶原移植物层并且放置在圆窗膜和包装层之间。 任选地,包装层可以封装在胶原移植物内。 任选地,可以从患者获得骨paté,并用于形成填充层的至少一部分。 任选地,可以在填充层和患者的窦鼓膜的骨之间的压缩下放置硅橡胶支撑。

    ANTIMICROBIAL GAS IMPREGNATING DEVICES AND METHODS
    10.
    发明申请
    ANTIMICROBIAL GAS IMPREGNATING DEVICES AND METHODS 有权
    抗微生物气体注入装置和方法

    公开(公告)号:US20100268149A1

    公开(公告)日:2010-10-21

    申请号:US12825373

    申请日:2010-06-29

    Abstract: A nitric oxide gas-releasing conduit configured for surgical implantation through a patient's tympanic membrane. The nitric oxide gas-releasing conduit comprises a gas-permeable cured resin material configured for releasably sequestering therein gas. The gas-permeable cured resin material is charged with nitric oxide gas. The nitric oxide gas-releasing conduit may be optionally coated with an antimicrobial gas-releasing composition. The gas-releasing coating composition may be configured to release nitric oxide.

    Abstract translation: 一氧化氮气体释放导管,其构造成用于通过患者的鼓膜进行手术植入。 一氧化氮气体释放导管包括构造成可释放地将其中的气体隔离的透气性固化树脂材料。 透气性固化树脂材料装有一氧化氮气体。 一氧化氮气体释放管道可任选地涂覆有抗微生物气体释放组合物。 气体释放涂料组合物可以被配置为释放一氧化氮。

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