公开(公告)号：US08497126B2

公开(公告)日：2013-07-30

申请号：US11824289

申请日：2007-06-29

申请人： Marie D. Bryhan ,  Paul E. Gagnon, Jr. ,  Zhong-he Shen ,  Oliva V. LaChance ,  Hongming Wang

发明人： Marie D. Bryhan ,  Paul E. Gagnon, Jr. ,  Zhong-he Shen ,  Oliva V. LaChance ,  Hongming Wang

IPC分类号： C12N5/02

CPC分类号： B29C59/14 ,  B29C59/142 ,  C12N5/0068 ,  C12N2533/30

摘要： A method of producing an improved cell growth surface and cell attachment surface. According to the present invention, a polymer article is molded at temperature in excess of 550° F. at the injection tip. After allowing the part to cool, a stream of plasma comprised of activated gaseous species generated by a microwave source is imparted on the article. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion superior to those of untreated polymer or polymer treated by other methods.

摘要翻译： 一种生产改良的细胞生长表面和细胞附着表面的方法。 根据本发明，聚合物制品在注射尖端处的模制温度超过550°F。 在使部件冷却之后，将由微波源产生的活化气态物质组成的等离子体流送到制品上。 该流以受控的方式指向聚合物基材的表面，使得表面具有优于未经处理的聚合物或通过其它方法处理的聚合物的细胞粘附的特性。

公开(公告)号：US20080003663A1

公开(公告)日：2008-01-03

申请号：US11824289

申请日：2007-06-29

申请人： Marie D. Bryhan ,  Paul E. Gagnon ,  Zhong-he Shen ,  Oliva V. LaChance ,  Hongming Wang

发明人： Marie D. Bryhan ,  Paul E. Gagnon ,  Zhong-he Shen ,  Oliva V. LaChance ,  Hongming Wang

IPC分类号： C12M3/00 ,  B29C35/08

CPC分类号： B29C59/14 ,  B29C59/142 ,  C12N5/0068 ,  C12N2533/30

摘要： A method of producing an improved cell growth surface and cell attachment surface. According to the present invention, a polymer article is molded at temperature in excess of 550° F. at the injection tip. After allowing the part to cool, a stream of plasma comprised of activated gaseous species generated by a microwave source is imparted on the article. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion superior to those of untreated polymer or polymer treated by other methods.

摘要翻译： 一种生产改良的细胞生长表面和细胞附着表面的方法。 根据本发明，聚合物制品在注射尖端处的模制温度超过550°F。 在使部件冷却之后，将由微波源产生的活化气态物质组成的等离子体流送到制品上。 该流以受控的方式指向聚合物基材的表面，使得表面具有优于未经处理的聚合物或通过其它方法处理的聚合物的细胞粘附的特性。

公开(公告)号：US06617152B2

公开(公告)日：2003-09-09

申请号：US09947035

申请日：2001-09-04

申请人： Marie D. Bryhan ,  Paul E. Gagnon ,  Oliva V. LaChance ,  Zhong-he Shen ,  Hongming Wang

发明人： Marie D. Bryhan ,  Paul E. Gagnon ,  Oliva V. LaChance ,  Zhong-he Shen ,  Hongming Wang

IPC分类号： C12M300

CPC分类号： B29C59/14 ,  B05D3/144 ,  B05D7/22 ,  B29C59/142

摘要： A method, apparatus and product for producing an advantaged cell growth surface. According to the present invention, a stream of plasma is comprised of activated gaseous species generated by a microwave source. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion far superior to that of untreated polymer or polymer treated by other known methods.

摘要翻译： 用于生产有利的细胞生长表面的方法，装置和产品。 根据本发明，等离子体流由微波源产生的活化气态物质组成。 该流以受控的方式指向聚合物基材的表面，使得该表面具有远优于未处理的聚合物或通过其它已知方法处理的聚合物的细胞粘附的特性。