公开(公告)号：US06641854B2

公开(公告)日：2003-11-04

申请号：US10282877

申请日：2002-10-29

申请人： Mark Gerhart ,  Edward O'Brien ,  Simon Gainey ,  Robert Guldi ,  Brian Wagner ,  Mike Richmond

发明人： Mark Gerhart ,  Edward O'Brien ,  Simon Gainey ,  Robert Guldi ,  Brian Wagner ,  Mike Richmond

IPC分类号： B65D300

CPC分类号： A47G19/02 ,  B65D81/3227

摘要： The invention discloses a method and an apparatus for a food container which includes an inner member (which can be a cup or a bottle) for holding a particulate food; an outer member (which can be a second cup or a second bottle) adapted to receive the inner member, with a space between the inner and the outer members, for a liquid food; where the inner member interlocks with the outer member and openings are provided for the discharge of the liquid food; and the particulate food and the liquid food can be consumed simultaneously by tilting the container towards the mouth of the user to discharge or withdraw particulate food from the inner member and liquid food from the outer member through the aperture.

摘要翻译： 本发明公开了一种用于食物容器的方法和装置，其包括用于保持颗粒状食物的内部构件（其可以是杯子或瓶子）; 适于接收内部构件的外部构件（其可以是第二杯或第二瓶），在内部和外部构件之间具有用于液体食物的空间; 其中内部构件与外部构件互锁并且开口用于排出液体食物; 并且通过使容器朝向使用者的嘴倾斜容器，可以同时消耗颗粒状食物和液体食物，以通过孔从外部构件和液体食物从内部构件和液体食物排出或从其中排出或从中抽出液体食物。

公开(公告)号：US06528105B1

公开(公告)日：2003-03-04

申请号：US09617676

申请日：2000-07-14

申请人： Mark Gerhart ,  Edward O'Brien ,  Simon Gainey ,  Robert Guldi ,  Brian Wagner ,  Mike Richmond

发明人： Mark Gerhart ,  Edward O'Brien ,  Simon Gainey ,  Robert Guldi ,  Brian Wagner ,  Mike Richmond

IPC分类号： B65D300

CPC分类号： A47G19/02 ,  B65D81/3227

摘要： The invention discloses a method and an apparatus for a food container which includes an inner member (which can be a cup or a bottle) for holding a particulate food; an outer member (which can be a second cup or a second bottle) adapted to receive the inner member, with a space between the inner and the outer members, for a liquid food; where the inner member interlocks with the outer member and openings are provided for the discharge of the liquid food; and the particulate food and the liquid food can be consumed simultaneously by tilting the container towards the mouth of the user to discharge or withdraw particulate food from the inner member and liquid food from the outer member through the aperture.

公开(公告)号：US20100115612A1

公开(公告)日：2010-05-06

申请号：US12255590

申请日：2008-10-21

申请人： Edward O'Brien ,  David Pett

发明人： Edward O'Brien ,  David Pett

IPC分类号： G06F12/14 ,  G06F17/30

CPC分类号： G06F15/0291 ,  G06F17/30575 ,  G06F21/41

摘要： Described are computer-based methods and apparatuses, including computer program products, for providing context-based user authentication, workflow processing and data management in a centralized application in communication with a plurality of third-party applications. Changed data from a first third-party application is received by a centralized application. The changed data is processed by the centralized application. The processing comprises determining an urgency type, a second third-party application to which at least a portion of the data is applicable, mapping the data to a second third-party application data structure, and generating a request including the data structure and based on the urgency type and the second third-party application. The request is sent to the second third-party application. Data in a database associated with the centralized application is updated based on the changed data.

摘要翻译： 描述了基于计算机的方法和装置，包括计算机程序产品，用于在与多个第三方应用程序通信的集中应用中提供基于上下文的用户认证，工作流处理和数据管理。 中央应用程序接收到来自第一个第三方应用程序的更改数据。 更改的数据由集中应用程序处理。 该处理包括确定紧急类型，至少部分数据可应用的第二第三方应用，将数据映射到第二第三方应用数据结构，以及生成包括数据结构的请求，并基于 紧急类型和第二个第三方应用程序。 该请求被发送到第二个第三方应用程序。 基于更改的数据更新与集中式应用程序相关联的数据库中的数据。

公开(公告)号：US08131666B2

公开(公告)日：2012-03-06

申请号：US12255590

申请日：2008-10-21

申请人： Edward O'Brien ,  David Pett

发明人： Edward O'Brien ,  David Pett

IPC分类号： G06F7/00 ,  G06F17/00

CPC分类号： G06F15/0291 ,  G06F17/30575 ,  G06F21/41

摘要： Described are computer-based methods and apparatuses, including computer program products, for providing context-based user authentication, workflow processing and data management in a centralized application in communication with a plurality of third-party applications. Changed data from a first third-party application is received by a centralized application. The changed data is processed by the centralized application. The processing comprises determining an urgency type, a second third-party application to which at least a portion of the data is applicable, mapping the data to a second third-party application data structure, and generating a request including the data structure and based on the urgency type and the second third-party application. The request is sent to the second third-party application. Data in a database associated with the centralized application is updated based on the changed data.

摘要翻译： 描述了基于计算机的方法和装置，包括计算机程序产品，用于在与多个第三方应用程序通信的集中应用中提供基于上下文的用户认证，工作流处理和数据管理。 中央应用程序接收到来自第一个第三方应用程序的更改数据。 更改的数据由集中应用程序处理。 该处理包括确定紧急类型，至少部分数据可应用的第二第三方应用，将数据映射到第二第三方应用数据结构，以及生成包括数据结构的请求，并基于 紧急类型和第二个第三方应用程序。 该请求被发送到第二个第三方应用程序。 基于更改的数据更新与集中式应用程序相关联的数据库中的数据。

公开(公告)号：US06575932B1

公开(公告)日：2003-06-10

申请号：US09728600

申请日：2000-12-01

申请人： Edward O'Brien ,  Marino Labinaz

发明人： Edward O'Brien ,  Marino Labinaz

IPC分类号： A61M2500

CPC分类号： A61M25/007 ,  A61M25/1011 ,  A61M2025/0008 ,  A61M2025/1015 ,  A61M2025/1052

摘要： The present invention pertains to a local delivery device comprising a distal catheter unit and a proximal catheter unit which may be positioned by sliding over the distal catheter unit. Both the distal and the proximal catheter units have separate inflatable occluding balloons. The slidable positioning of the catheter units in relation to each other provides for variable inter-balloon distances, which in turn provides for a variably sized occlusion region in a hollow tubular organ, for example a vessel. Dispersed on the catheter shaft between the two occluding balloons are multiple infusion ports through which therapeutic agents may be delivered to an occluded region of a hollow tubular organ. The local delivery device may further comprise a quantifying device for determining the distance between the two occluding balloons. Therefore, precise adjustment of the inter-balloon distance permits controlled delivery of therapeutics to a discreet length of the hollow tubular organ wall.

摘要翻译： 本发明涉及一种局部递送装置，其包括远端导管单元和近端导管单元，其可以通过在远端导管单元上滑动而定位。 远端导管和近端导管单元都具有分开的可充气闭塞气囊。 导管单元相对于彼此的可滑动定位提供了可变的气球间距离，这进一步提供了中空管状器官（例如血管）中可变尺寸的闭塞区域。 分散在两个闭塞球囊之间的导管轴上的是多个输注端口，治疗剂可通过该输注端口被输送到空心管状器官的闭塞区域。 本地递送装置还可以包括用于确定两个闭塞球囊之间的距离的量化装置。 因此，气球间距离的精确调节允许治疗剂的控制递送到中空管状器官壁的谨慎长度。

公开(公告)号：US08914516B2

公开(公告)日：2014-12-16

申请号：US13466713

申请日：2012-05-08

申请人： Christopher Warren ,  John P. Hake ,  Edward O'Brien

发明人： Christopher Warren ,  John P. Hake ,  Edward O'Brien

IPC分类号： G06F15/173

CPC分类号： G06Q40/02

摘要： Methods and apparatuses, including computer program products, are described for providing an integrated suite of cloud-based, hosted, and internal applications. A server receives from a client device a request to access a portal comprising a plurality of cloud-based, hosted, and internal applications. The server determines an identity of the user, and one or more applications of the plurality of applications available for access by the user. The server establishes a link with one or more computing devices hosting the one or more available applications for providing functionality of the available applications. The server authenticates the user automatically for each of the available applications, and translates communications between the server and each of the applications based on a mapping configuration. The server integrates the established links into a user interface that provide access to each of the available applications, and provides the integrated user interface to the client device.

摘要翻译： 描述了包括计算机程序产品在内的方法和设备，用于提供基于云，托管和内部应用的集成套件。 服务器从客户端设备接收访问包括多个基于云，托管和内部应用的门户的请求。 服务器确定用户的身份以及可由用户访问的多个应用的​​一个或多个应用。 服务器与承载一个或多个可用应用的一个或多个计算设备建立链接，以提供可用应用的功能。 服务器为每个可用应用程序自动认证用户，并根据映射配置翻译服务器与每个应用程序之间的通信。 服务器将建立的链路集成到提供对每个可用应用程序的访问的用户界面中，并向客户端设备提供集成的用户界面。

公开(公告)号：US20130304797A1

公开(公告)日：2013-11-14

申请号：US13466713

申请日：2012-05-08

申请人： Christopher Warren ,  John P. Hake ,  Edward O'Brien

发明人： Christopher Warren ,  John P. Hake ,  Edward O'Brien

IPC分类号： G06F15/16

CPC分类号： G06Q40/02

摘要： Methods and apparatuses, including computer program products, are described for providing an integrated suite of cloud-based, hosted, and internal applications. A server receives from a client device a request to access a portal comprising a plurality of cloud-based, hosted, and internal applications. The server determines an identity of the user, and one or more applications of the plurality of applications available for access by the user. The server establishes a link with one or more computing devices hosting the one or more available applications for providing functionality of the available applications. The server authenticates the user automatically for each of the available applications, and translates communications between the server and each of the applications based on a mapping configuration. The server integrates the established links into a user interface that provide access to each of the available applications, and provides the integrated user interface to the client device.

摘要翻译： 描述了包括计算机程序产品在内的方法和设备，用于提供基于云，托管和内部应用的集成套件。 服务器从客户端设备接收访问包括多个基于云，托管和内部应用的门户的请求。 服务器确定用户的身份以及可由用户访问的多个应用的​​一个或多个应用。 服务器与承载一个或多个可用应用的一个或多个计算设备建立链接，以提供可用应用的功能。 服务器为每个可用应用程序自动认证用户，并根据映射配置翻译服务器与每个应用程序之间的通信。 服务器将建立的链路集成到提供对每个可用应用程序的访问的用户界面中，并向客户端设备提供集成的用户界面。

公开(公告)号：US20090054340A1

公开(公告)日：2009-02-26

申请号：US12228261

申请日：2008-08-11

申请人： Yong-Xiang Chen ,  Xiaoli Ma ,  Edward O'Brien ,  Katey Rayner

发明人： Yong-Xiang Chen ,  Xiaoli Ma ,  Edward O'Brien ,  Katey Rayner

IPC分类号： A61K38/16 ,  A61P9/10

CPC分类号： A61K31/565 ,  A61K38/1709

摘要： A method of preventing or treating cardiovascular disease is provided. The method comprises administering heat shock protein 27 (HSP27), a co-factor, variant or analogue thereof. The cardiovascular disease can include atherosclerosis. A pharmaceutical composition comprising HSP27 for use in the prevention or treatment of cardiovascular disease is also provided.

摘要翻译： 提供了一种预防或治疗心血管疾病的方法。 该方法包括施用热休克蛋白27（HSP27），其辅助因子，其变体或类似物。 心血管疾病可包括动脉粥样硬化。 还提供了包含用于预防或治疗心血管疾病的HSP27的药物组合物。

公开(公告)号：US20050023065A1

公开(公告)日：2005-02-03

申请号：US10874963

申请日：2004-06-23

申请人： Timothy McBride ,  Edward O'Brien ,  David Hatch

发明人： Timothy McBride ,  Edward O'Brien ,  David Hatch

IPC分类号： G01G3/14 ,  B60R21/01 ,  B60R21/015 ,  G01G19/12 ,  G01G19/414 ,  G01G19/52 ,  G01G23/01 ,  B60K28/00

CPC分类号： B60R21/01516 ,  B60R21/0152 ,  G01G19/4142

摘要： An occupant weight sensor (1) for placement between a frame (7) fixed to the chassis of a vehicle and a second frame (8) supporting a vehicle seat has a sense element having a first body (12, 22, 28, 34, 50, 62, 64, 68) formed with a planar sense surface on which are mounted piezoresistors electrically connected in a Wheatstone bridge configuration. A post (12a, 22c, 28c, 34e, 50b, 62a, 64a, 68b) extends outwardly from the first body for attachment to the first frame. A second body is formed with a force transfer portion (14a, 24g, 30d, 36b, 52a, 70a) permanently attached to the first body along an outer periphery circumscribing the sense surface. The piezoresistors are electrically connected to conditioning electronics received in a chamber formed between the two bodies. The effects of parasitic loads on the sense element are minimized by selected placement of the piezoresistors on the sense surface. Several variations are disclosed for attaching the sensor to the first and second frames and both longitudinally and laterally extending electrical connectors are shown.

摘要翻译： 用于放置在固定到车辆的底盘的框架（7）和支撑车辆座椅的第二框架（8）之间的乘员体重传感器（1）具有感测元件，该感测元件具有第一主体（12,22,28,34， 50,62,64,68）形成有平面感测表面，其上安装有以惠斯通电桥配置电连接的压电电阻。 柱（12a，22c，28c，34e，50b，62a，64a，68b）从第一主体向外延伸以附接到第一框架。 第二主体形成有沿着与感测表面相邻的外周永久地附接到第一主体的力传递部分（14a，24g，30d，36b，52a，70a）。 压敏电阻器电连接到容纳在形成在两个主体之间的腔室中的调节电子器件。 通过在感测表面上选择放置压敏电阻，使寄生负载对感应元件的影响最小化。 公开了用于将传感器附接到第一和第二框架的几个变型，并且示出了纵向和横向延伸的电连接器。