公开(公告)号：US20100108577A1

公开(公告)日：2010-05-06

申请号：US12545624

申请日：2009-08-21

申请人： Mark M. Wang ,  Eugene Tu ,  Luis M. Pestana ,  Andrew E. Senyei ,  James P. O'Connell ,  Tina S. Nova ,  Kristie L. Lykstad ,  Jeffrey M. Hall ,  William F. Butler

发明人： Mark M. Wang ,  Eugene Tu ,  Luis M. Pestana ,  Andrew E. Senyei ,  James P. O'Connell ,  Tina S. Nova ,  Kristie L. Lykstad ,  Jeffrey M. Hall ,  William F. Butler

IPC分类号： B07C5/36

CPC分类号： G01N15/1463 ,  B07C5/34 ,  G01N15/1459 ,  G01N30/02 ,  G01N2015/1486 ,  G01N2015/149 ,  H05H3/04 ,  B01D2015/3895

摘要： Apparatus and methods are provided for interacting light with particles, including but not limited to biological matter such as cells, in unique and highly useful ways. Optophoresis consists of subjecting particles to various optical forces, especially optical gradient forces, and more particularly moving optical gradient forces, so as to obtain useful results. In biology, this technology represents a practical approach to probing the inner workings of a living cell, preferably without any dyes, labels or other markers. In one aspect, a particle may be characterized by determining its optophoretic constant or signature. For example, a diseased cell has a different optophoretic constant from a healthy cell, thereby providing information, or the basis for sorting. In the event of physical sorting, various forces may be used for separation, including fluidic forces, such as through the use of laminar flow, or optical forces, or mechanical forces, such as through adhesion. Various techniques for measuring the dielectric constant of particles are provided.

摘要翻译： 提供了用于以独特且非常有用的方式将光与颗粒（包括但不限于生物物质如细胞）相互作用的装置和方法。 电渗疗法包括使颗粒经受各种光学力，特别是光学梯度力，尤其是移动的光学梯度力，从而获得有用的结果。 在生物学中，该技术代表了探测活细胞内部运作的实际方法，优选没有任何染料，标签或其他标记物。 在一个方面，粒子的特征可以在于确定其荧光特性常数或特征。 例如，患病细胞与健康细胞具有不同的视觉波动常数，从而提供信息或分选的基础。 在物理分选的情况下，各种力可以用于分离，包括流体力，例如通过使用层流，或光学力，或机械力，例如通过粘附。 提供了用于测量颗粒的介电常数的各种技术。

公开(公告)号：US20080186449A1

公开(公告)日：2008-08-07

申请号：US12025716

申请日：2008-02-04

申请人： Sudipto Sur ,  Luis M. Pestana

发明人： Sudipto Sur ,  Luis M. Pestana

IPC分类号： A61B3/113

CPC分类号： A61B3/113 ,  G06K9/00604

摘要： Systems and methods for facilitating gaze tracking based on multiple images are disclosed. A gaze tracking system includes an optical module configured to receive illumination from a target and provide a background and tracking channel outputs, the background channel including ambient illumination and the tracking channel including ambient and controlled added illumination at a targeted range of wavelengths. The background and tracking channel outputs are provided to an imaging module configured to provide an associated set of background and tracking images to a processor module to facilitate gaze tracking. Controlled illumination of the target may be provided by an illumination element, in conjunction with the processor module, to facilitate gaze tracking.

摘要翻译： 公开了一种便于基于多个图像的凝视跟踪的系统和方法。 注视跟踪系统包括被配置为从目标接收照明并提供背景和跟踪通道输出的光学模块，所述背景通道包括环境照明和跟踪通道，包括在目标波长范围内的环境和受控的附加照明。 将背景和跟踪通道输出提供给成像模块，该成像模块被配置为向处理器模块提供相关联的背景和跟踪图像集以便于注视跟踪。 可以通过与处理器模块结合的照明元件来提供目标的受控照明，以便于注视跟踪。

公开(公告)号：US07682025B2

公开(公告)日：2010-03-23

申请号：US12025716

申请日：2008-02-04

申请人： Sudipto Sur ,  Luis M. Pestana

发明人： Sudipto Sur ,  Luis M. Pestana

IPC分类号： A61B3/14

CPC分类号： A61B3/113 ,  G06K9/00604

摘要： Systems and methods for facilitating gaze tracking based on multiple images are disclosed. A gaze tracking system includes an optical module configured to receive illumination from a target and provide a background and tracking channel outputs, the background channel including ambient illumination and the tracking channel including ambient and controlled added illumination at a targeted range of wavelengths. The background and tracking channel outputs are provided to an imaging module configured to provide an associated set of background and tracking images to a processor module to facilitate gaze tracking. Controlled illumination of the target may be provided by an illumination element, in conjunction with the processor module, to facilitate gaze tracking.

摘要翻译： 公开了一种便于基于多个图像的凝视跟踪的系统和方法。 注视跟踪系统包括被配置为从目标接收照明并提供背景和跟踪通道输出的光学模块，所述背景通道包括环境照明和跟踪通道，包括在目标波长范围内的环境和受控的附加照明。 将背景和跟踪通道输出提供给成像模块，该成像模块被配置为向处理器模块提供相关联的背景和跟踪图像集以便于注视跟踪。 可以通过与处理器模块结合的照明元件来提供目标的受控照明，以便于注视跟踪。

公开(公告)号：US20090268045A1

公开(公告)日：2009-10-29

申请号：US12185752

申请日：2008-08-04

申请人： Sudipto Sur ,  Luis M. Pestana

发明人： Sudipto Sur ,  Luis M. Pestana

IPC分类号： H04N5/228 ,  G06K9/40

CPC分类号： G06K9/2018 ,  G06K9/00604 ,  H04N5/2254 ,  H04N5/2352 ,  H04N5/332

摘要： Apparatus and methods for enhancing the performance of an imager in applications such as gaze tracking are described. An enhanced image sensor includes a sensor pixel array, a filter array optically coupled to the pixel array and a filter map including data associated with one or more characteristics of the filter array. The filter array characteristics can be preconfigured and/or dynamically reconfigured to allow for wavelength specific pixel capture, with the filter map correspondingly adjusted in response to changes in the filter array characteristics.

摘要翻译： 描述了用于在诸如注视跟踪的应用中增强成像器的性能的装置和方法。 增强图像传感器包括传感器像素阵列，光学耦合到像素阵列的滤波器阵列和包括与滤波器阵列的一个或多个特性相关联的数据的滤波器图。 滤波器阵列特性可以被预配置和/或动态地重新配置以允许波长特定的像素捕获，其中滤波器映射根据滤波器阵列特性的变化相应地被调整。