Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers
    1.
    发明申请
    Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers 审中-公开
    测定采用电化学发光标记和电化学发光淬灭剂

    公开(公告)号:US20060035248A1

    公开(公告)日:2006-02-16

    申请号:US11124407

    申请日:2005-05-09

    IPC分类号: C12Q1/68

    摘要: This invention pertains to the general field of chemical and biological assays which employ electrochemiluminescence (ECL), also referred to as electrogenerated chemiliminescence. More particularly, the present invention pertains to certain classes of chemical moieties which strongly quench ECL, and the use of these ECL quenchers in combination with ECL labels, for example, in ECL assay methods which employ an ECL quencher and an ECL label. One class of such quenching moieties are those which comprise at least one benzene moiety. Sub-classes of such quenching moieties are those which comprise at least one phenol moiety, quinone moiety, benzene carboxylic acid, and/or benzene carboxylate moiety.

    摘要翻译: 本发明涉及使用电化学发光(ECL)的化学和生物测定的一般领域,也被称为电生化学发光。 更具体地说,本发明涉及强烈猝灭ECL的某些类别的化学部分,以及这些ECL猝灭剂与ECL标记的组合的使用,例如在采用ECL猝灭剂和ECL标记的ECL测定方法中。 一类这样的猝灭部分是包含至少一个苯部分的那些。 这种猝灭部分的亚类是包含至少一个苯酚部分,醌部分,苯羧酸和/或苯羧酸酯部分的那些。