公开(公告)号：US06528619B1

公开(公告)日：2003-03-04

申请号：US09402641

申请日：2000-01-10

申请人： Markus Bürgle ,  Heinrich Graeff ,  Horst Kessler ,  Viktor Magdolen ,  Bernhard König ,  Marcus Koppitz ,  Christoph Riemer ,  Manfred Schmitt ,  Ulrich Weidle

发明人： Markus Bürgle ,  Heinrich Graeff ,  Horst Kessler ,  Viktor Magdolen ,  Bernhard König ,  Marcus Koppitz ,  Christoph Riemer ,  Manfred Schmitt ,  Ulrich Weidle

IPC分类号： C07K708

CPC分类号： C12N9/6462 ,  C12Y304/21073

摘要： The present invention provides peptides as inhibitors of the binding of urokinase to the urokinase receptor. The peptides have the general structural formula (I): X1-[X2]n-X3-X4-K-Y-F-X5-X6-I-X7-W-[X8]m  (I) in which X1, X2, X3, X4, X5, X6, X7 and X8 each denote an aminocarboxylic acid, n and m are each independently 0 or 1, K denotes an aminocarboxylic acid with a lysine side chain, Y denotes an aminocarboxylic acid with a tyrosine side chain, F denotes an aminocarboxylic acid with a phenyl-alanine side chain, I denotes an aminocarboxylic acid with an isoleucine side chain, W denotes an aminocarboxylic acid with a tryptophan side chain, and the monomeric building blocks are linked by —CONR1— or —NR1CO— bonds where R1 in each case independently denotes hydrogen, methyl or ethyl, and pharmaceutically compatible salts and derivatives thereof.

摘要翻译： 本发明提供肽作为尿激酶与尿激酶受体结合的抑制剂。 肽具有通式结构式（I）：其中X 1，X 2，X 3，X 4，X 5，X 6，X 7和X 8各自表示氨基羧酸，n和m各自独立地为0或1，K表示氨基羧酸， 赖氨酸侧链，Y表示具有酪氨酸侧链的氨基羧酸，F表示具有苯基 - 丙氨酸侧链的氨基羧酸，I表示具有异亮氨酸侧链的氨基羧酸，W表示具有色氨酸侧链的氨基羧酸， 并且单体结构单元通过-CONR1-或-NR1CO-键连接，其中R 1在每种情况下独立地表示氢，甲基或乙基，以及其药学上相容的盐和衍生物。

公开(公告)号：US07821028B2

公开(公告)日：2010-10-26

申请号：US12317334

申请日：2008-12-22

申请人： Bernhard König

发明人： Bernhard König

IPC分类号： H01L29/66 ,  H01L21/04

CPC分类号： H01L29/8611 ,  H01L29/417 ,  H01L29/66128

摘要： A power semiconductor component and a method for producing such a component. The component comprises a semiconductor base body having a first doping. A pn junction is formed in the base body by a contact region having a second doping with a first doping profile. A field ring structure has a second doping with a second doping profile. The contact region and the field ring structure are arranged at respectively assigned first and second partial areas of a first surface of the base body. Both extend into the base body, wherein the base body has, for the field ring structure, a trench-type cutout assigned to each respective field ring, the surface of said cutout following the contour of the assigned doping profile.

摘要翻译： 功率半导体元件及其制造方法。 该组件包括具有第一掺杂的半导体基体。 通过具有第一掺杂分布的第二掺杂的接触区域在基体中形成pn结。 场环结构具有第二掺杂，具有第二掺杂分布。 接触区域和场环结构被布置在基体的第一表面的分别分配的第一和第二部分区域。 两者都延伸到基体中，其中，对于场环结构，基体具有分配给每个相应的场环的沟槽型切口，所述切口的表面遵循所分配的掺杂轮廓的轮廓。

公开(公告)号：US20130327718A1

公开(公告)日：2013-12-12

申请号：US13981814

申请日：2012-01-19

申请人： Walter Adami ,  Hubert Angert ,  Bernhard König ,  Steffen Krück ,  Frank Dieter Kuhn ,  Martin Lietzenmayer ,  Egon Walzer ,  Corinna Schmidt ,  Nobuhiro Muraoka

发明人： Walter Adami ,  Hubert Angert ,  Bernhard König ,  Steffen Krück ,  Frank Dieter Kuhn ,  Martin Lietzenmayer ,  Egon Walzer ,  Corinna Schmidt ,  Nobuhiro Muraoka

IPC分类号： B63J4/00

CPC分类号： B63J4/002 ,  C02F1/008 ,  C02F1/70 ,  C02F1/722 ,  C02F2103/008 ,  C02F2209/001 ,  C02F2209/05 ,  C02F2209/40 ,  C02F2303/04 ,  C02F2303/18

摘要： A device comprising a measuring device for determining the flow rate of a water stream, a measuring device for determining the concentration of hydrogen peroxide in the water stream, a measuring device for determining the concentration of peracetic acid in the water stream, a metering device for metering a reducing agent into the water stream downstream of the measuring devices for the concentrations, and a control device which, from the flow rate of the water stream, the concentration of hydrogen peroxide in the water stream and the concentration of peracetic acid in the water stream, calculates an amount of reducing agent for reducing the content of hydrogen peroxide and peracetic acid to a desired value and actuates the metering device for metering the reducing agent, makes possible reliable reduction of the content of hydrogen peroxide and peracetic acid in a water stream. The device is suitable for reducing the content of hydrogen peroxide and peracetic acid in a water stream which is withdrawn from ballast water tanks of a ship.

摘要翻译： 一种装置，包括用于确定水流的流量的测量装置，用于确定水流中过氧化氢浓度的测量装置，用于确定水流中过乙酸浓度的测量装置，用于 将还原剂计量到用于浓度的测量装置下游的水流中;以及控制装置，根据水流的流量，水流中的过氧化氢浓度和水中过乙酸的浓度 计算用于将过氧化氢和过乙酸的含量降低到所需值的还原剂的量并且致动用于计量还原剂的计量装置，使得可以可靠地降低水流中过氧化氢和过乙酸的含量 。 该装置适用于减少从船舶的压载水箱中取出的水流中过氧化氢和过乙酸的含量。

公开(公告)号：US08096206B2

公开(公告)日：2012-01-17

申请号：US11999365

申请日：2007-12-05

申请人： Bernhard König

发明人： Bernhard König

IPC分类号： G05G9/047

CPC分类号： G05G9/047 ,  G05G2009/04718 ,  Y10T74/20201

摘要： The invention relates to a control device, in particular for an aircraft, having a multiaxially tiltable joystick for the actuation of signal transducers, in particular for the pitch control and roll control of an aircraft, as well as having a cardan-like joint by means of which the joystick is tiltable about different pivot axes, said joint furthermore having at least one freewheel for a tilt movement of the joystick about one of the pivot axes. In accordance with the invention, the freewheel is formed by a lever mechanism or by an elastic component.

摘要翻译： 本发明涉及一种特别是用于飞行器的控制装置，其具有用于致动信号传感器的多轴可倾斜操纵杆，特别是用于飞行器的桨距控制和侧倾控制，以及通过装置具有万丝节形接头 其中操纵杆可围绕不同的枢转轴线倾斜，所述接头还具有用于操纵杆围绕其中一个枢转轴线的倾斜运动的至少一个空转轮。 根据本发明，自由轮由杠杆机构或弹性部件形成。

公开(公告)号：US07791176B2

公开(公告)日：2010-09-07

申请号：US12317338

申请日：2008-12-22

申请人： Bernhard König

发明人： Bernhard König

IPC分类号： H01L29/06

CPC分类号： H01L29/8611 ,  H01L29/0619 ,  H01L29/404 ,  H01L29/417 ,  H01L29/66128

摘要： A power semiconductor component and method for producing it. The component has a semiconductor base body with a first doping and a pn junction formed by a contact region having a second doping with a doping profile in the base body. The second contact region is arranged at a second surface of the base body and extends into the base body. The base body has a trench-type cutout with an edge area and a base area, wherein the base area is formed as a second partial area of the second surface, and wherein the second contact region extends from the base area via the edge area as far as a first partial area. Furthermore, the pn junction has a curvature adjacent to the edge area.

摘要翻译： 功率半导体元件及其制造方法。 该部件具有半导体基体，其具有第一掺杂和由在基体中具有掺杂分布的第二掺杂的接触区形成的pn结。 第二接触区域布置在基体的第二表面并延伸到基体中。 基体具有边缘区域和基部区域的沟槽型切口，其中基部区域形成为第二表面的第二部分区域，并且其中第二接触区域从基部区域经由边缘区域延伸为 作为第一个部分区域。 此外，pn结具有与边缘区域相邻的曲率。

公开(公告)号：US07108625B2

公开(公告)日：2006-09-19

申请号：US10849687

申请日：2004-05-19

申请人： Bernhard König

发明人： Bernhard König

IPC分类号： F16H3/72

CPC分类号： F16H37/0826

摘要： An apparatus for generating a rotational movement of a shaft with a first device for generating a rotational movement, driving a first drive path, and a second device for generating a rotational movement, driving a second drive path, at least one rotatable planet pinion being arranged on the shaft and the first drive path engaging with the planet pinion via an inner toothed wheel work of a ring gear and the second drive path engaging with the planet pinion via an outer toothed wheel work of a sun wheel.

摘要翻译： 一种用于产生具有用于产生旋转运动的第一装置的轴的旋转运动的装置，用于产生旋转运动的第一驱动路径和用于产生旋转运动的第二装置，驱动第二驱动路径的装置，至少一个可转动的行星小齿轮被布置 所述轴和所述第一驱动路径经由环形齿轮的内齿轮工作与所述行星齿轮啮合，并且所述第二驱动路径经由太阳轮的外齿轮工作与所述行星齿轮啮合。