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公开(公告)号:US06194174B1
公开(公告)日:2001-02-27
申请号:US09310275
申请日:1999-05-12
申请人: Martin K R Burnham , Leslie Marie Palmer , John Peter Throup , Stephanie Van Horn , Richard Lloyd Warren
发明人: Martin K R Burnham , Leslie Marie Palmer , John Peter Throup , Stephanie Van Horn , Richard Lloyd Warren
IPC分类号: C12N510
CPC分类号: C12N9/1205 , A61K38/00 , A61K48/00 , C12Q1/689
摘要: The invention provides 636 HK polypeptides and polynucleotides encoding 636 HK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing 636 HK polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了636个HK多肽和编码636个HK多肽的多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用636个HK多肽筛选抗菌化合物的方法。
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公开(公告)号:US07202071B2
公开(公告)日:2007-04-10
申请号:US10437581
申请日:2003-05-14
申请人: Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
发明人: Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
摘要: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供第p多肽和编码第p多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用第p多肽筛选抗菌化合物的方法。
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公开(公告)号:US06303771B1
公开(公告)日:2001-10-16
申请号:US09080643
申请日:1998-05-18
申请人: Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
发明人: Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
IPC分类号: C12N1531
摘要: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供第p多肽和编码第p多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用第p多肽筛选抗菌化合物的方法。
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公开(公告)号:US06548281B1
公开(公告)日:2003-04-15
申请号:US09642000
申请日:2000-08-18
申请人: Karen M O'Dwyer , Deborah D Jaworski , Jeffrey L Mooney , Lisa K Shilling , John Peter Throup , Nicola Gail Wallis , Yi Yi Zhong , Min Wang
发明人: Karen M O'Dwyer , Deborah D Jaworski , Jeffrey L Mooney , Lisa K Shilling , John Peter Throup , Nicola Gail Wallis , Yi Yi Zhong , Min Wang
IPC分类号: C12N912
CPC分类号: G01N33/573 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K14/31 , C12N9/12
摘要: The invention provides Histidine Kinase polypeptides and polynucleotides encoding Histidine Kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine Kinase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供组氨酸激酶多肽和编码组氨酸激酶多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用组氨酸激酶多肽筛选抗菌化合物的方法。
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