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公开(公告)号:US06586578B1
公开(公告)日:2003-07-01
申请号:US08911844
申请日:1997-08-15
IPC分类号: C07H2102
摘要: The invention provides Defl polypeptides and DNA (RNA) encoding Defl polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Defl polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了Def1多肽和编码Def1多肽的DNA(RNA)和通过重组技术产生这种多肽的方法。 还提供了利用Def1多肽筛选抗菌化合物的方法。
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公开(公告)号:US06410263B1
公开(公告)日:2002-06-25
申请号:US09015189
申请日:1998-01-29
IPC分类号: C07H2104
CPC分类号: C12N9/1223 , A61K39/00
摘要: The invention provides histidine kinase polypeptides and polynucleotides encoding histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing histidine kinase polypeptides to screen for antibacterial compounds.
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公开(公告)号:US06346395B1
公开(公告)日:2002-02-12
申请号:US09239052
申请日:1999-01-27
申请人: Alison Francis Chalker , Christine Debouck , David John Holmes , Karen Anne Ingraham , Deborah Dee Jaworski , Anna Lisa Kosmatka , Damien McDevitt , Jeffrey Mooney , Stewart C Pearson , Chi Yong So , Nicola Gail Wallis , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人: Alison Francis Chalker , Christine Debouck , David John Holmes , Karen Anne Ingraham , Deborah Dee Jaworski , Anna Lisa Kosmatka , Damien McDevitt , Jeffrey Mooney , Stewart C Pearson , Chi Yong So , Nicola Gail Wallis , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号: C12D2106
CPC分类号: C12N9/0006 , A61K38/00 , C12Y101/011
摘要: The invention provides FabG polypeptides and polynucleotides encoding FabG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing FabG polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了FabG多肽和编码FabG多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用FabG多肽筛选抗菌化合物的方法。
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公开(公告)号:US06335433B1
公开(公告)日:2002-01-01
申请号:US08965902
申请日:1997-11-07
申请人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
发明人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
IPC分类号: C07H2102
CPC分类号: C12N9/0093 , A61K38/00 , A61K39/00 , C12N9/1096 , C12N9/78
摘要: The invention provides nrdD polypeptides and DNA (RNA) encoding nrdD polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nrdD polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了nrdD多肽和编码nrdD多肽的DNA(RNA),以及通过重组技术产生此类多肽的方法。 还提供了利用nrdD多肽筛选抗菌化合物的方法。
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公开(公告)号:US06326462B1
公开(公告)日:2001-12-04
申请号:US09491916
申请日:2000-01-27
申请人: Christine Debouck , Jason Craig Fedon , Deborah Dee Jaworski , Jeffrey Mooney , Leslie Marie Palmer , Christopher Michael Traini , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人: Christine Debouck , Jason Craig Fedon , Deborah Dee Jaworski , Jeffrey Mooney , Leslie Marie Palmer , Christopher Michael Traini , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号: A61K3902
CPC分类号: C12N9/1085 , A61K38/00
摘要: The invention provides ribH polypeptides and polynucleotides encoding ribH polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribH polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供ribH多肽和编码ribH多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribH多肽筛选抗菌化合物的方法。
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公开(公告)号:US06280971B1
公开(公告)日:2001-08-28
申请号:US09227806
申请日:1999-01-11
申请人: Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Y Zhong
发明人: Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Y Zhong
IPC分类号: C12N1231
CPC分类号: C12Y305/04025 , C07K2319/00 , C12N9/78
摘要: The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供ribA多肽和编码ribA多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribA多肽筛选抗菌化合物的方法。
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公开(公告)号:US06274719B1
公开(公告)日:2001-08-14
申请号:US09066512
申请日:1998-04-24
申请人: Sanjoy Biswas , Alison Frances Chalker , David Holmes , Karen A Ingraham , Leslie Marie Palmer , Jennifer E Ray , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , Alison Frances Chalker , David Holmes , Karen A Ingraham , Leslie Marie Palmer , Jennifer E Ray , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C07H2104
CPC分类号: C12N9/80 , A61K38/00 , C07K14/3156 , Y10S530/82 , Y10S530/825
摘要: The invention provides gcp polypeptides and polynucleotides encoding gcp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gcp polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了gcp多肽和编码gcp多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用gcp多肽筛选抗菌化合物的方法。
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公开(公告)号:US06270992B1
公开(公告)日:2001-08-07
申请号:US08963901
申请日:1997-11-04
申请人: Nicola Gail Wallis , Christopher Michael Traini , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Richard Lloyd Warren
发明人: Nicola Gail Wallis , Christopher Michael Traini , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Richard Lloyd Warren
IPC分类号: C12N500
CPC分类号: C12N9/1223 , A61K39/00 , A61K2039/51
摘要: The invention provides Histidine kinase polypeptides and polynucleotides encoding Histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine kinase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供组氨酸激酶多肽和编码组氨酸激酶多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用组氨酸激酶多肽筛选抗菌化合物的方法。
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公开(公告)号:US06268177B1
公开(公告)日:2001-07-31
申请号:US09285576
申请日:1999-04-02
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N1500
CPC分类号: C12N9/1077
摘要: The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ndp polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了ndp多肽和编码ndp多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ndp多肽筛选抗菌化合物的方法。
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公开(公告)号:US06245891B1
公开(公告)日:2001-06-12
申请号:US09285515
申请日:1999-04-02
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C07K100
CPC分类号: C07K14/3156
摘要: The invention provides nusB polypeptides and polynucleotides encoding nusB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nusB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了编码nusB多肽的nusB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用nusB多肽筛选抗菌化合物的方法。
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