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公开(公告)号：US20070042942A1
公开(公告)日：2007-02-22
申请号：US11589614
申请日：2006-10-30
申请人： Martin Linsell , Paul Fatheree , Michael Leadbetter , Yan Zhu , J. Judice
发明人： Martin Linsell , Paul Fatheree , Michael Leadbetter , Yan Zhu , J. Judice
CPC分类号： B82Y5/00 , A61K9/0014 , A61K9/0019 , A61K38/00 , A61K47/40 , A61K47/6951 , C07K9/008
摘要： Disclosed are glycopeptide derivatives substituted at the C-terminus and/or the R-terminus with a substituent that comprises one or more saccharide groups and a carboxy group; and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
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公开(公告)号：US20050159344A1
公开(公告)日：2005-07-21
申请号：US11080130
申请日：2005-03-15
申请人： Martin Linsell , Paul Fatheree , Michael Leadbetter , Yan Zhu , J. Judice
发明人： Martin Linsell , Paul Fatheree , Michael Leadbetter , Yan Zhu , J. Judice
CPC分类号： B82Y5/00 , A61K9/0014 , A61K9/0019 , A61K38/00 , A61K47/40 , A61K47/6951 , C07K9/008
摘要： Disclosed are glycopeptide derivatives substituted at the C-terminus and/or the R-terminus with a substituent that comprises one or more saccharide groups and a carboxy group; and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
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3.发明申请公开(公告)号：US20080103292A1
公开(公告)日：2008-05-01
申请号：US11977377
申请日：2007-10-24
申请人： J. Judice , Paul Fatheree , Bernice Lam , Michael Leadbetter , Martin Linsell , YongQi Mu , Sean Trapp , Guang Yang , Yan Zhu
发明人： J. Judice , Paul Fatheree , Bernice Lam , Michael Leadbetter , Martin Linsell , YongQi Mu , Sean Trapp , Guang Yang , Yan Zhu
IPC分类号： C07K14/00
摘要： Disclosed are derivatives of glycopeptide compounds having at least one substituent of the formula: —Ra—Y—Rb-(Z)x where Ra, Rb, Y, Z and x are as defined, and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
摘要翻译： 公开了具有至少一个下式的取代基的糖肽化合物的衍生物：<？in-line-formula description =“In-line formula”end =“lead”？> - < （Z） <？in-line-formula description =“In-line Formulas”end =“tail”？>其中R a
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公开(公告)号：US06455669B1
公开(公告)日：2002-09-24
申请号：US09674456
申请日：2000-11-01
申请人： J. Kevin Judice , Paul Ross Fatheree , Bernice M. T. Lam , Michael Leadbetter , Martin Sheringham linsell , YongQi Mu , Sean Gary Trapp , Guang Yang , Yan Zhu
发明人： J. Kevin Judice , Paul Ross Fatheree , Bernice M. T. Lam , Michael Leadbetter , Martin Sheringham linsell , YongQi Mu , Sean Gary Trapp , Guang Yang , Yan Zhu
IPC分类号： C07K750
摘要： Disclosed are derivatives of glycopeptide compounds having at least one substituent of the formula: —Ra—Y—Rb—(Z)x where Ra, Rb, Y, Z and x are as defined, and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
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公开(公告)号：US08481386B2
公开(公告)日：2013-07-09
申请号：US12757812
申请日：2010-04-09
申请人： Jianlin Liu , Dengtao Zhao , Yan Zhu , Ruigang Li , Bei Li
发明人： Jianlin Liu , Dengtao Zhao , Yan Zhu , Ruigang Li , Bei Li
IPC分类号： H01L21/336
CPC分类号： H01L29/7881 , H01L21/28273 , H01L29/42332 , H01L29/66825
摘要： In one embodiment, a memory device includes a substrate, a tunneling oxide, a silicide nanocrystal floating gate, and a control oxide. The tunneling oxide is positioned upon a first surface of the substrate, the silicide nanocrystal floating gate is positioned upon the tunneling oxide, and the control oxide positioned upon the nanocrystal floating gate.
摘要翻译： 在一个实施例中，存储器件包括衬底，隧道氧化物，硅化物纳米晶体浮动栅极和控制氧化物。 隧道氧化物位于衬底的第一表面上，硅化物纳米晶体浮栅位于隧道氧化物上，并且控制氧化物位于纳米晶体浮栅上。
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6.发明申请公开(公告)号：US20120193060A1
公开(公告)日：2012-08-02
申请号：US13442628
申请日：2012-04-09
申请人： Arnie Fulton , Yan Zhu , Michael Bomar
发明人： Arnie Fulton , Yan Zhu , Michael Bomar
摘要： A die casting process using pattern recognition techniques to identify those die castings manufactured under conditions likely to produce a die casting which would subsequently prove unacceptable for use. By promptly identifying such die castings, they may be discarded before being shipped to a remote facility for further processing. As a result, the rejection rate of die castings at the remote facility may be reduced and the raw materials used to form the discarded die castings may be more readily recycled.
摘要翻译： 使用模式识别技术的压铸方法来识别在可能产生压铸件的条件下制造的那些压铸件，随后将被证明是不可接受的。 通过及时识别这种压铸件，在运送到远程设备进行进一步处理之前，可将其丢弃。 结果，可以减少远程设备的压铸件的排出率，并且用于形成废弃压铸件的原材料可以更容易地再循环。
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公开(公告)号：US08227495B2
公开(公告)日：2012-07-24
申请号：US12541865
申请日：2009-08-14
申请人： Xin Chen , Peng Cheng , L. Edward Clemens , Jeffrey D. Johnson , Jingyuan Ma , Alison Murphy , Imad Nashashibi , Christopher J. Rabbat , Jiangao Song , Maria E. Wilson , Yan Zhu , Zuchun Zhao
发明人： Xin Chen , Peng Cheng , L. Edward Clemens , Jeffrey D. Johnson , Jingyuan Ma , Alison Murphy , Imad Nashashibi , Christopher J. Rabbat , Jiangao Song , Maria E. Wilson , Yan Zhu , Zuchun Zhao
IPC分类号： A61K31/425
CPC分类号： A61K31/506 , A61K31/454 , C07D277/42 , C07D401/04 , C07D401/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The present disclosure provides 2,4-disubstituted thiazoles of the general structure shown below that are agonists of G-protein coupled receptor (IC-GPCR2). Also, provided are compositions comprising these compounds as well as methods for using these compounds in a variety of applications including diabetes and metabolic disorders.
摘要翻译： 本公开提供了下列通式结构的2,4-二取代噻唑，它是G-蛋白偶联受体（IC-GPCR2）的激动剂。 此外，提供了包含这些化合物的组合物以及在各种应用中使用这些化合物的方法，包括糖尿病和代谢紊乱。
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公开(公告)号：US08121741B2
公开(公告)日：2012-02-21
申请号：US12118481
申请日：2008-05-09
申请人： Jeffrey D. Taft , Yan Zhu
发明人： Jeffrey D. Taft , Yan Zhu
IPC分类号： G05D3/12 , G05D5/00 , G05D9/00 , G05D17/00 , G05B23/02 , G08C19/20 , G08C19/04 , G08C19/10 , G06F11/00
CPC分类号： G01D4/004 , Y02B90/242 , Y02B90/245 , Y04S20/322 , Y04S20/40
摘要： A method of managing an electric utility grid includes geographically grouping a set of customer electric usage meters to create a set of fine sensors on a power grid. Each usage meter in the grouped set is capable of being remotely monitored, and each usage meter is at a different location along the power line. If a power anomaly is detected at the subset of meters, then power to the electric utility grid is adjusted to correct the anomaly.
摘要翻译： 一种管理电力公用电网的方法包括在一组用户电力使用量度表上进行地理分组，以在电网上创建一组精细的传感器。 分组组中的每个使用度量表能够被远程监控，并且每个使用度量表位于沿着电力线的不同位置。 如果在米的子集上检测到电力异常，则调整到电力公用电网的电力以校正异常。
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9.发明申请METHODS FOR DRUG DELIVERY COMPRISING UNFOLDING AND FOLDING PROTEINS AND PEPTIDE NANOPARTICLES 有权药物递送方法包括未折叠和折叠蛋白质和肽类纳米颗粒公开(公告)号：US20110059181A1
公开(公告)日：2011-03-10
申请号：US12851600
申请日：2010-08-06
申请人： Yiqiao Hu , Jinhui Wu , Dawei Ding , Guangming Gong , Xiaolei Tang , Chunhui Tong , Yan Zhu , Shaoling Li
发明人： Yiqiao Hu , Jinhui Wu , Dawei Ding , Guangming Gong , Xiaolei Tang , Chunhui Tong , Yan Zhu , Shaoling Li
IPC分类号： A61K9/14 , A61K31/337 , A61K31/352 , A61P35/00 , B05D7/00 , B82Y5/00 , B82Y40/00
CPC分类号： A61K9/19 , A61K9/5138 , A61K9/5192 , A61K31/337
摘要： The present invention provides preparation methods of protein nanoparticles for in vivo delivery of pharmacologically active agents, wherein said methods are to encase pharmaceutically active agents into proteins or peptides to form nanoparticles by unfolding the protein, and subsequently refolding or assembling the protein to produce a pharmacologically active agent encased within a protein nanoparticle.
摘要翻译： 本发明提供用于体内递送药理学活性剂的蛋白质纳米颗粒的制备方法，其中所述方法是通过展开蛋白质将药物活性剂包裹在蛋白质或肽中以形成纳米颗粒，并随后重折叠或组装蛋白质以产生药理学 活性剂包裹在蛋白质纳米颗粒内。
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公开(公告)号：US20110023599A1
公开(公告)日：2011-02-03
申请号：US12694001
申请日：2010-01-26
申请人： Yan Zhu , Xiaoying Zhu
发明人： Yan Zhu , Xiaoying Zhu
IPC分类号： G01M1/16
摘要： A device to balance a disc, comprising a shaft disposed for rotation about an axis having one end adapted to coaxially receive the disc and an opposite end including rotor structure stator structure to magnetically drive the rotor structure, shaft and disc about the axis; and structure for determining imbalance in the disc.
摘要翻译： 一种用于平衡盘的装置，包括设置成用于围绕具有适于同轴地容纳盘的一端的轴线旋转的轴和包括转子结构定子结构的相对端，用于围绕轴线磁性驱动转子结构，轴和盘; 以及用于确定盘不平衡的结构。
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