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公开(公告)号：US20070116658A1
公开(公告)日：2007-05-24
申请号：US11655134
申请日：2007-01-19
申请人： Masahiro Tajima , Youichi Shimatani , Masashi Ogou
发明人： Masahiro Tajima , Youichi Shimatani , Masashi Ogou
IPC分类号： A61K8/73
摘要： A hair tonic composition containing adenosine, adenosine 5′-phosphate, and/or an adenosine 5′-phosphate salt as an active ingredient.
摘要翻译： 含有腺苷，腺苷5'-磷酸，和/或腺苷5'-磷酸盐作为有效成分的发丝组合物。
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公开(公告)号：US07182939B2
公开(公告)日：2007-02-27
申请号：US10113940
申请日：2002-04-02
申请人： Masahiro Tajima , Youichi Shimatani , Masashi Ogou
发明人： Masahiro Tajima , Youichi Shimatani , Masashi Ogou
IPC分类号： A61K7/06
摘要： A hair tonic composition containing adenosine, adenosine 5′-phosphate, and/or an adenosine 5′-phosphate salt as an active ingredient.
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公开(公告)号：US20070299032A1
公开(公告)日：2007-12-27
申请号：US10578507
申请日：2004-11-10
申请人： Ritsuko Ehama , Masato Iino , Yosuke Nakazawa , Masahiro Tajima , Masashi Ogou , Seiji Arase
发明人： Ritsuko Ehama , Masato Iino , Yosuke Nakazawa , Masahiro Tajima , Masashi Ogou , Seiji Arase
IPC分类号： A61K31/7076 , A61P17/14 , C12Q1/68
CPC分类号： G01N33/5008 , A61K8/606 , A61Q5/00 , A61Q7/00 , G01N2333/475 , G01N2500/10
摘要： The present invention provides a method for maintaining and promoting hair thickening by increasing the expression of keratinocyte growth factor (FGF-7) in hair follicle cells, and preferably dermal papilla cells, a composition for increasing expression of FGF-7 that contains adenosine and/or a derivative thereof, and particularly, an external scalp preparation for maintaining and promoting hair thickening.
摘要翻译： 本发明提供一种通过增加毛囊细胞中角质形成细胞生长因子（FGF-7）的表达并优选皮肤乳头细胞来维持和促进毛发增稠的方法，用于增加含有腺苷和/ 或其衍生物，特别是用于保持和促进毛发增厚的外用头皮制剂。
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公开(公告)号：US6139852A
公开(公告)日：2000-10-31
申请号：US47447
申请日：1998-03-25
申请人： Eriko Takeoka , Chika Hamada , Jun Suzuki , Yosuke Nakazawa , Tsutomu Souma , Masashi Ogou , Masahiro Tajima
发明人： Eriko Takeoka , Chika Hamada , Jun Suzuki , Yosuke Nakazawa , Tsutomu Souma , Masashi Ogou , Masahiro Tajima
CPC分类号： A61K8/361 , A61K8/97 , A61Q7/00 , Y10S514/88
摘要： A hair growth phase extender containing, as an effective ingredient, at least one compound selected from the group consisting of unsaturated fatty acid and/or its derivatives, especially an unsaturated fatty acid having the formula:C.sub.n H.sub.m O.sub.2where n is 12 to 28 and m is n+1 to 2n-2; or containing, as an effective ingredient, an extract of a plant belonging to the Coriandrum.
摘要翻译： 毛发生长期延长剂含有作为有效成分的至少一种选自不饱和脂肪酸和/或其衍生物的化合物，特别是具有下式的不饱和脂肪酸：CnHmO2，其中n为12〜28，m为n +1到2n-2; 或含有作为有效成分的属于Coriandrum的植物的提取物。
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公开(公告)号：US20070249915A1
公开(公告)日：2007-10-25
申请号：US10574469
申请日：2004-09-30
申请人： Hirofumi Aoki , Tatsuhiro Kodama , Kiyotaka Hasegawa , Kentaro Kajiya , Yumiko Ishimatatsu , Masashi Ogou , Seiichi Yoshida , Jiro Kishimoto , Osamu Moro
发明人： Hirofumi Aoki , Tatsuhiro Kodama , Kiyotaka Hasegawa , Kentaro Kajiya , Yumiko Ishimatatsu , Masashi Ogou , Seiichi Yoshida , Jiro Kishimoto , Osamu Moro
IPC分类号： A61B5/00
CPC分类号： C12Q1/6883 , C12Q2600/158
摘要： The present invention provides a skin test method for predicting the formation of spots in the skin. This method judges skin to be susceptible to the formation of spots in the case expression in the epidermis of MCP-2 gene, a polynucleotide capable of hybridizing under highly stringent conditions to mouse AK012157 gene, human FLJ21763 gene or rat S74257 gene, or Mcp9, Mcp10, Isg15, Usp18, Oas12, Gbp2, Gtpi, Ifi47, Igtp, Tgtp, Sprr2A, Krt2-6b, Cdk5rap2, Mef2C, Gsta4, Osf2, Tnc, Igfbp6, Ppicap or Mm. 74656 gene, is increased as compared with normal expression in the epidermis.
摘要翻译： 本发明提供一种用于预测皮肤斑点形成的皮肤试验方法。 该方法可以判断皮肤易于在MCP-2基因的表皮中表达的斑点形成，该基因是能够在高度严格条件下与小鼠AK012157基因，人FLJ21763基因或大鼠S74257基因或Mcp9基因杂交的多核苷酸， Mcp10，Isg15，Usp18，Oas12，Gbp2，Gtpi，Ifi47，Igtp，Tgtp，Sprr2A，Krt2-6b，Cdk5rap2，Mef2C，Gsta4，Osf2，Tnc，Igfbp6，Ppicap或Mm。 74656基因与表皮正常表达相比增加。
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