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    Thiazolidin-4-one derivatives and acid addition salts thereof useful for treating PAF mediated diseases
    1.
    发明授权
    Thiazolidin-4-one derivatives and acid addition salts thereof useful for treating PAF mediated diseases 失效
    噻唑烷-4-酮衍生物及其适用于治疗PAF介导性疾病的酸添加物

    公开(公告)号：US5106860A

    公开(公告)日：1992-04-21

    申请号：US624566

    申请日：1990-12-10

    申请人： Masao Enomoto ,  Atsuyuki Kojima ,  Yoshihiro Komuro ,  Shigeaki Morooka ,  Shunji Aono ,  Yuzuru Sanemitsu ,  Masato Mizutani ,  You Tanabe

    发明人： Masao Enomoto ,  Atsuyuki Kojima ,  Yoshihiro Komuro ,  Shigeaki Morooka ,  Shunji Aono ,  Yuzuru Sanemitsu ,  Masato Mizutani ,  You Tanabe

    IPC分类号： C07D417/04

    CPC分类号： C07D417/04

    摘要： Thiazolidin-4-one derivative represented by the following general formula (I) and acid addition salts thereof ##STR1## wherein; R.sup.1 and R.sup.2 are the same or different and denote each(i) a residue represented by the general formula--A--R.sup.4 wherein, A denotes a single bond, C.sub.1 -C.sub.8 alkylene, C.sub.2 -C.sub.8 alkenylene, or C.sub.2 -C.sub.8 alkynylene and R.sup.4 denotes hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, or C.sub.1 -C.sub.6 haloalkyl,or(ii) a residue represented by the general formula ##STR2## wherein, B denotes a single bond or C.sub.1 -C.sub.6 alkylene, R.sup.5 denotes hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, substituted silyl, or substituted or unsubstituted aryl, n and n' denote each an integer of 2 to 4, m denotes an integer of 1 to 3, and m' denotes an integer of 0 to 2;R.sup.3 denotes hydrogen, C.sub.1 -C.sub.2 alkyl, allyl, 2-propynyl,or(c) the general formula--F--R.sup.9 wherein, F denotes C.sub.2 -C.sub.6 alkylene and R.sup.9 denotes a nitrogen-containing heterocyclic aromatic residue or an amino group represented by the general formula ##STR3## (R.sup.10 denotes hydrogen, C.sub.2 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkanoyl and R.sup.11 denotes hydrogen or C.sub.1 -C.sub.4 alkyl or R.sup.10 in combination with R.sup.11 denotes a 5- to 7-membered cyclic amino group which optionally contains other hetero atoms.Having selective PAF-antagonistic activities, these compounds are very useful as preventive and curative agents for PAF-induced diseases, for example, various kinds of inflammation, allergic diseases, circulatory diseases, and gastro-intestinal diseases.

    Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor
    2.
    发明授权
    Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor 失效
    可用于治疗血小板活化因子引起的疾病的噻唑烷-4-酮衍生物

    公开(公告)号：US4992455A

    公开(公告)日：1991-02-12

    申请号：US196058

    申请日：1988-05-19

    申请人： Masao Enomoto ,  Atsuyuki Kojima ,  Yoshihiro Komuro ,  Shigeaki Morooka ,  Shunji Aono ,  Yuzuru Sanemitsu ,  Masato Mizutani ,  You Tanabe

    发明人： Masao Enomoto ,  Atsuyuki Kojima ,  Yoshihiro Komuro ,  Shigeaki Morooka ,  Shunji Aono ,  Yuzuru Sanemitsu ,  Masato Mizutani ,  You Tanabe

    IPC分类号： C07D417/04

    CPC分类号： C07D417/04

    摘要： Thiazolidin-4-one derivative represented by the folowing general formula (I) and acid addition salts thereof ##STR1## wherein; R.sup.1 and R.sup.2 are the same or different and denote each(i) a residue represented by the general formula--A--R.sup.4 wherein, A denotes a single bond, C.sub.1 -C.sub.8 alkylene, C.sub.2 -C.sub.8 alkenylene, or C.sub.2 -C.sub.8 alkynylene and R.sup.4 denotes hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, or C.sub.1 -C.sub.6 haloalkyl, or(ii) a residue represented by the general formula{(CH.sub.2).sub.n O}.sub.m {(CH.sub.2).sub.n' O}B--R.sup.5 wherein, B denotes a single bond or C.sub.1 -C.sub.6 alkylene, R.sup.5 denotes hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, substituted silyl, or substituted or unsubstituted aryl, n and n' denote each an integer of 2 to 4, m denotes an integer of 1 to 3, and m' denotes an integer of 0 to 2; andR.sup.3 denotes hydrogen, C.sub.1 -C.sub.2 alkyl, allyl, 2-propynyl, or a residue represented by(a) the general formula--CH.sub.2).sub.l R.sup.6 wherein, R.sup.6 denotes halogen, an aryl group substituted or unsubstituted by one or more hydroxy or C.sub.1 -C.sub.4 alkoxy groups, or a residue represented by the general formula --D--R.sup.7 (D denotes oxygen or sulfur and R.sup.7 denotes hydrogen, C.sub.1 -C.sub.4 alkyl, or C.sub.1 -C.sub.4 alkanol) and l denotes an integer of 2 to 4,(b) the general formula--CH.sub.2).sub.k CO--E--R.sup.8 wherein, E denotes oxygen, sulfur, imino, or C.sub.1 -C.sub.4 alkylimino, R.sup.8 denotes hydrogen or C.sub.1 -C.sub.4 alkyl, or --(E--R.sup.8) denotes a 5- to 7-membered cyclic amino group which optionally contains other hetero atoms, and k denotes an integer of 1 to 3, or(c) the general formula--F--R.sup.9 wherein, F denotes C.sub.2 -C.sub.6 alkylene and R.sup.9 denotes a nitrogen-containing heterocyclic aromatic residue or an amino group represented by the general formula ##STR2## (R.sup.10 denotes hydrogen, C.sub.1 -C.sub.4 alkyl, or C.sub.1 -C.sub.4 alkyl or R.sup.10 in combination with R.sup.11 denotes a 5- to 7-membered cyclic amino group which optionally contains other hetero atoms), with the proviso that, when R.sup.1 is hydrogen and R.sup.2 is methyl, R.sup.3 denotes hydrogen, C.sub.1 -C.sub.2 alkyl, 2-propynyl, or a residue represented by(a) the general formula--CH.sub.2).sub.l R.sup.6 wherein, R.sup.6 denotes halogen, an aryl group substituted or unsubstituted by one or more hydroxy or C.sub.1 -C.sub.4 alkoxy groups, or a residue represented by the general formula --D--R.sup.7 (D denotes oxygen or sulfur and R.sup.7 denotes hydrogen, C.sub.1 -C.sub.4 alkyl, or C.sub.1 -C.sub.4 alkanoyl) and l denotes an integer of 2 to 4,(b) the general formula--CH.sub.2).sub.k CO--E--R.sup.8 wherein, E denotes oxygen, sulfur, imino, or C.sub.1 -C.sub.4 alkylimino, R.sup.8 denotes hydrogen or C.sub.1 -C.sub.4 alkyl, or --(E--R.sup.8) denotes a 5- to 7-membered cyclic amino group which optionally contains other hetero atoms, and k denotes an integer of 1 to 3, or(c) the general formula--F--R.sup.9 wherein, F denotes C.sub.2 -C.sub.6 alkylene and R.sup.9 denotes a nitrogen-containing heterocyclic aromatic residue or an amino group represented by the general formula ##STR3## (R.sup.10 denotes hydrogen, C.sub.2 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkanoyl and R.sup.11 denotes hydrogen or C.sub.1 -C.sub.4 alkyl or R.sup.10 in combination with R.sup.11 denotes a 5- to 7-membered cyclic amino group which optionally contains other hetero atoms.Having selective PAF-antagonistic activities, these compounds are very useful as preventive and curative agents for PAF-induced diseases, for example, various kinds of inflammation, allergic diseases, circulatory diseases, and gastro-intestinal diseases.

    Power Tool
    5.
    发明申请
    Power Tool 有权
    电动工具

    公开(公告)号：US20080265695A1

    公开(公告)日：2008-10-30

    申请号：US12104590

    申请日：2008-04-17

    申请人： Kenichirou Yoshida ,  Katsuhiro Oomori ,  Yoshihiro Komuro ,  Kazutaka Iwata

    发明人： Kenichirou Yoshida ,  Katsuhiro Oomori ,  Yoshihiro Komuro ,  Kazutaka Iwata

    IPC分类号： H02K7/14

    CPC分类号： H02K7/145 ,  B25F5/02 ,  H02K5/20 ,  H02K9/06 ,  H02K2211/03

    摘要： A power tool includes a housing, a brushless motor, and a cover member. The housing has an air intake hole and an air exhaust hole formed therein, the housing having an inner surface. The brushless motor has an outer surface disposed in the housing, a first endface near the air intake hole, and a second endface near the air exhaust hole. The cover member covers at least one of the first endface and the second endface for preventing dust from entering the brushless motor. The inner surface of the housing and outer surface of the brushless motor define a circulation path providing communication between the air intake hole and the air exhaust hole.

    摘要翻译： 电动工具包括壳体，无刷电动机和盖构件。 壳体具有形成在其中的进气孔和排气孔，壳体具有内表面。 无刷电动机具有设置在壳体中的外表面，靠近进气孔的第一端面和靠近排气孔的第二端面。 盖构件覆盖第一端面和第二端面中的至少一个，用于防止灰尘进入无刷电动机。 壳体的内表面和无刷电动机的外表面限定了提供进气孔和排气孔之间的连通的循环路径。

    Electric tool with closable air ports
    7.
    发明授权
    Electric tool with closable air ports 有权
    具有可关闭气孔的电动工具

    公开(公告)号：US07832499B2

    公开(公告)日：2010-11-16

    申请号：US12132601

    申请日：2008-06-03

    申请人： Yoshihiro Komuro ,  Katsuhiro Oomori

    发明人： Yoshihiro Komuro ,  Katsuhiro Oomori

    IPC分类号： E21B3/00

    CPC分类号： B25F5/008

    摘要： An electric tool includes a housing; a motor that is housed in the housing; and a tip tool. A rotation transmission mechanism transmits a rotation of the motor to the tip tool. An air inlet is disposed on the housing to introduce a cooling air for cooling the motor from an outside of the housing and an air outlet is disposed to discharge the cooling air. A cover is slidable along an inner wall or an outer wall of the housing and is movable in a first position where the air inlet and the air outlet are opened and a second position where the air inlet and the air outlet are closed.

    摘要翻译： 电动工具包括壳体; 容纳在壳体中的电动机; 和一个提示工具。 旋转传递机构将电机的旋转传递到尖端工具。 空气入口设置在壳体上以引入用于从外壳的外部冷却马达的冷却空气，并且设置空气出口以排出冷却空气。 盖可以沿着壳体的内壁或外壁滑动，并且可以在空气入口和空气出口打开的第一位置和空气入口和空气出口关闭的第二位置移动。

    Power Tool
    8.
    发明申请
    Power Tool 有权
    电动工具

    公开(公告)号：US20120200181A1

    公开(公告)日：2012-08-09

    申请号：US13446355

    申请日：2012-04-13

    申请人： Kenichirou Yoshida ,  Katsuhiro Oomori ,  Yoshihiro Komuro ,  Kazutaka Iwata

    发明人： Kenichirou Yoshida ,  Katsuhiro Oomori ,  Yoshihiro Komuro ,  Kazutaka Iwata

    IPC分类号： H02K7/14

    CPC分类号： H02K7/145 ,  B25F5/02 ,  H02K5/20 ,  H02K9/06 ,  H02K2211/03

    摘要： A power tool includes a housing, a brushless motor, and a cover member. The housing has an air intake hole and an air exhaust hole formed therein, the housing having an inner surface. The brushless motor has an outer surface disposed in the housing, a first endface near the air intake hole, and a second endface near the air exhaust hole. The cover member covers at least one of the first endface and the second endface for preventing dust from entering the brushless motor. The inner surface of the housing and outer surface of the brushless motor define a circulation path providing communication between the air intake hole and the air exhaust hole.

    摘要翻译： 电动工具包括壳体，无刷电动机和盖构件。 壳体具有形成在其中的进气孔和排气孔，壳体具有内表面。 无刷电动机具有设置在壳体中的外表面，靠近进气孔的第一端面和靠近排气孔的第二端面。 盖构件覆盖第一端面和第二端面中的至少一个，用于防止灰尘进入无刷电动机。 壳体的内表面和无刷电动机的外表面限定了提供进气孔和排气孔之间的连通的循环路径。

    POWER TOOL
    9.
    发明申请
    POWER TOOL 有权
    电动工具

    公开(公告)号：US20100244592A1

    公开(公告)日：2010-09-30

    申请号：US12530200

    申请日：2008-06-17

    申请人： Katsuhiro Oomori ,  Yoshihiro Komuro ,  Kenichirou Yoshida ,  Kazutaka Iwata

    发明人： Katsuhiro Oomori ,  Yoshihiro Komuro ,  Kenichirou Yoshida ,  Kazutaka Iwata

    IPC分类号： H02K7/14 ,  H02K9/06 ,  H02K11/04

    CPC分类号： B25F5/008 ,  H02K5/20 ,  H02K7/145 ,  H02K9/06

    摘要： According to an aspect of the present invention, there is provided a power tool including: a housing having a suction port formed thereon to introduce an cooling air from an outside of the housing; and a brushless motor that is housed in the housing and has an electric circuit, the electric circuit having a heat radiating surface, wherein the heat radiating surface is disposed in a neighborhood of the suction port.

    摘要翻译： 根据本发明的一个方面，提供了一种动力工具，包括：壳体，其上形成有用于从壳体的外部引入冷却空气的吸入口; 以及容纳在所述壳体中并具有电路的无刷电动机，所述电路具有散热面，所述散热面配置在所述吸入口附近。