公开(公告)号：US20170335334A1

公开(公告)日：2017-11-23

申请号：US15521943

申请日：2015-10-29

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Peter A. Carr ,  Bijan Zakeri

IPC: C12N15/74 ,  G06F19/24 ,  C12N15/87 ,  C12Q1/68

CPC classification number: C12N15/74 ,  C12N15/87 ,  C12Q1/68 ,  G16B40/00 ,  C12Q2521/507 ,  C12Q2563/185

Abstract: The disclosure relates to the use of steganographic methods to camouflage information encoded on nucleic acids. Specifically, the method comprising preparing a pool of recombinant nucleic acid constructs, wherein at least one of the constnjcts comprises the nucleic acid sequence to be camouflaged and wherein the pool is heterogeneous with respect to the orientation of the nucleic acid sequence to be camouflaged, and the information is camouflaged using genetic recombination.

公开(公告)号：US20170338943A1

公开(公告)日：2017-11-23

申请号：US15521956

申请日：2015-10-29

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Peter A. Carr ,  Bijan Zakeri

IPC: H04L9/06 ,  G09C1/00 ,  C12Q1/68

CPC classification number: H04L9/06 ,  C12Q1/68 ,  C12Q1/6869 ,  G09C1/00 ,  H04L9/00 ,  H04L9/0656 ,  H04L9/0866 ,  C12Q2563/185

Abstract: In some aspects, the instant disclosure relates to the multiplexed encryption of information on nucleic acid molecules. In some aspects, the instant disclosure relates to a method of secure communication of information disseminated across at least one nucleic acid molecule, the method comprising (a) obtaining a modified keyboard comprising a personalized platform for translating text into a nucleic acid sequence; (b) translating a quantum of information into a nucleic acid message sequence using the modified keyboard of (a); and, (c) obtaining an at least one nucleic acid molecule, each molecule comprising: (i) the complete or a portion of the nucleic acid message sequence, and (ii) at least one contiguous stretch of randomized variable nucleic acid sequence flanking and/or inserted into the message sequence, thereby producing a nucleic acid molecule or a set of nucleic acid molecules containing the entire quantum of information.