公开(公告)号：US20210038871A1

公开(公告)日：2021-02-11

申请号：US16965633

申请日：2019-01-15

Applicant: Massachusetts Institute of Technology

Inventor： Xuanhe Zhao ,  Hyunwoo Yuk ,  Xinyue Liu ,  Shaoting Lin ,  German Alberto Parada Hermandez

IPC: A61M31/00 ,  A61F5/00

Abstract: An expandable hydrogel structure formed of a housing with a superabsorbent material disposed and sealed therein, particularly wherein the housing is fabricated of a hydrogel membrane with a plurality of macropores providing fluid communication between the superabsorbent material and an exterior of the housing. Exposure of the superabsorbent material to an expansion trigger expands the housing from an initial size to an expanded size that is at least about 50 times to at least about 100 times the initial size. One or more therapeutic agents can further be disposed within the housing to provide controlled release of the therapeutic agents from the expanded housing for extended periods.