公开(公告)号：US20240399019A1

公开(公告)日：2024-12-05

申请号：US18606479

申请日：2024-03-15

Applicant: Massachusetts Institute of Technology

Inventor： Jingjing Wu ,  Jue Deng ,  Hyunwoo Yuk ,  Xuanhe Zhao

IPC: A61L24/00 ,  A61L24/10 ,  A61N1/05

Abstract: Methods of implanting biomaterials and devices in a patient, such as methods that include arranging an adhesive composition between and in contact with a biomaterial or a device, and a surface of a tissue of the patient. An adhesive composition may be configured to form at a surface of a tissue a conformal interface that reduces or minimizes infiltration of inflammatory cells at the conformal interface.

公开(公告)号：US11749247B2

公开(公告)日：2023-09-05

申请号：US17507491

申请日：2021-10-21

Applicant: Massachusetts Institute of Technology

Inventor： Evelyn N. Wang ,  Gang Chen ,  Xuanhe Zhao ,  Elise M. Strobach ,  Bikramjit S. Bhatia ,  Lin Zhao ,  Sungwoo Yang ,  Lee A. Weinstein ,  Thomas A. Cooper ,  Shaoting Lin

IPC: B32B3/02 ,  G10K11/168 ,  B32B7/027 ,  B32B7/12 ,  B32B9/04 ,  E06B9/24

CPC classification number: G10K11/168 ,  B32B7/027 ,  B32B7/12 ,  B32B9/045 ,  E06B9/24 ,  B32B2255/10 ,  B32B2255/20 ,  B32B2305/026 ,  B32B2307/102 ,  B32B2307/304 ,  B32B2307/412 ,  B32B2307/54 ,  B32B2307/546 ,  B32B2307/72 ,  E06B2009/2417

Abstract: Described herein are window retrofits including a monolithic silica aerogel slab having (i) an average haze value of 94% at 8 mm thickness. The window retrofit can be bonded to a glass sheet.

公开(公告)号：US20210386497A1

公开(公告)日：2021-12-16

申请号：US17458114

申请日：2021-08-26

Applicant: Massachusetts Institute of Technology

Inventor： Xuanhe Zhao ,  Yoonho Kim

IPC: A61B34/00 ,  A61B34/20 ,  B25J9/16

Abstract: Robotic devices and methods for performing minimally invasive procedures on the vascular system, particularly cerebrovascular and endovascular neurosurgical procedures, where a submillimeter-scale continuum robotic device is configured and adapted for active steering and navigation based on external magnetic actuation. The submillimeter-scale continuum robotic device includes an elongate body having an inner core and an outer shell, where the outer shell is fabricated of an elastomeric material having a plurality of ferromagnetic particles dispersed therein.

公开(公告)号：US20210106951A1

公开(公告)日：2021-04-15

申请号：US17068239

申请日：2020-10-12

Applicant: Massachusetts Institute of Technology

Inventor： Omar Labban ,  Grace Goon ,  John H. Lienhard ,  Xuanhe Zhao

IPC: B01D65/02

Abstract: Enhanced cleaning of a fouled membrane is achieved via controlled deformation in a method wherein a feed composition, comprising a solvent and dissolved components, flows into a retentate side of a membrane module. The solvent passes through the membrane from the retentate side to a permeate or draw side of the membrane module while retaining the dissolved components on the membrane. As a foulant accumulates on either side of the membrane, a driving force is generated across the membrane, wherein the membrane responds cyclically by deforming back and forth toward the permeate or draw side and toward the retentate side. The foulant is dislodged from the membrane via mechanical fatigue at the foulant-membrane interface caused by the deformation of the membrane and contact with a spacer in contact with the membrane.

公开(公告)号：US20200299466A1

公开(公告)日：2020-09-24

申请号：US16807533

申请日：2020-03-03

Applicant: Massachusetts Institute of Technology

Inventor： Xuanhe Zhao ,  Hyunwoo Yuk ,  Baoyang Lu

IPC: C08J3/075 ,  C08G61/12 ,  C08F212/14 ,  H01B1/12

Abstract: Pure conducting hydrogel precursors and hydrogels formed of pure conducting polymer materials having a combination of high electrical conductivity, high stretchability, low Young's modulus, superior mechanical, electrical and electrochemical stability, and tunable swelling behaviors in wet physiological environments. The hydrogel precursors and hydrogels are fabricated by adding a polar organic solvent to an aqueous solution of the pure conducting polymer material, followed by controlled dry-annealing to form a hydrogel precursor which can be subsequently rehydrated to form a pure conducting polymer hydrogel which comprises at least 99% of the pure conducting polymer.

公开(公告)号：US12209207B2

公开(公告)日：2025-01-28

申请号：US17833101

申请日：2022-06-06

Applicant: Massachusetts Institute of Technology

Inventor： Gang Chen ,  Xuanhe Zhao ,  Shaoting Lin ,  Yoichiro Tsurimaki

IPC: C09J183/06 ,  C09J7/24 ,  C09J7/30

Abstract: The present disclosure generally relates to a stretchable anti-fogging tape (SAT) that can be applied to diverse transparent materials with varied curvatures for persistent fogging prevention. The SAT comprises three synergistically-combined transparent layers: i) a stretchable middle layer with high elastic recovery to keep transparent materials tightly bound; ii) an anti-fogging top layer to impart hydrophilicity to transparent materials; and iii) an adhesive bottom layer to form robust yet reversible adhesion between transparent materials and SATs. The SAT can be configured to have water condensate form a predominantly continuous film thereon in response to a high humidity environment At least two applications are demonstrated, including the SAT-adhered eyeglasses and goggles for clear fog-free vision, and the SAT-adhered condensation cover for efficient solar-powered freshwater production.

公开(公告)号：US20240238476A1

公开(公告)日：2024-07-18

申请号：US18421735

申请日：2024-01-24

Applicant: Massachusetts Institute of Technology

Inventor： Xuanhe Zhao ,  Hyunwoo Yuk

IPC: A61L24/00 ,  A61B5/00 ,  A61B5/11 ,  A61K9/70 ,  A61L24/04 ,  B32B9/02 ,  B32B29/00 ,  A61F13/00

CPC classification number: A61L24/0031 ,  A61B5/1102 ,  A61B5/68335 ,  A61K9/7084 ,  A61L24/043 ,  B32B9/02 ,  B32B29/002 ,  A61B2562/0261 ,  A61F2013/00676 ,  B32B2307/7163 ,  B32B2307/748 ,  B32B2405/00 ,  B32B2535/00

Abstract: A method of adhering wet tissues together includes providing a dry adhesive material that contains one or more hydrophilic polymers, one or more amine coupling groups, and one or more cross linkers. The method including the steps of placing the dry adhesive material in contact with one or more wet tissue surfaces; allowing the dry adhesive material to absorb liquid from the one or more wet surfaces to thereby swell the adhesive material; allowing instant crosslinking by intermolecular interactions between the adhesive material and the one or more wet surfaces; and allowing quick covalent crosslinking between the adhesive material and the one or more wet surfaces.

公开(公告)号：US20240132758A1

公开(公告)日：2024-04-25

申请号：US18535124

申请日：2023-12-11

Applicant: Massachusetts Institute of Technology ,  Mayo Foundation for Medical Education and Research

Inventor： Xuanhe Zhao ,  Hyunwoo Yuk ,  Xinyu Mao ,  Christoph Nabzdyk

IPC: C09J105/08 ,  A61L24/00 ,  C09J9/00 ,  C09J11/06 ,  C09J133/02 ,  C09J151/00

CPC classification number: C09J105/08 ,  A61L24/0042 ,  A61L24/0094 ,  C09J9/00 ,  C09J11/06 ,  C09J133/02 ,  C09J151/003 ,  A61L2400/04 ,  C09J2483/00

Abstract: A tissue adhesive material that provides fast and robust adhesion even on tissue surfaces covered in bodily fluids. The tissue adhesive material is formed of a hydrophobic matrix and a plurality of bioadhesive microparticles dispersed within the hydrophobic matrix configured such that disposing the adhesive material directly on a fluid covered surface and applying pressure causes the (a) hydrophobic matrix to repel the fluid, (b) the bioadhesive particles to compress forming an adhesive layer, and (c) the bioadhesive particles to form temporary crosslinks followed by covalent crosslinks with the surface.

公开(公告)号：US11779422B2

公开(公告)日：2023-10-10

申请号：US17458114

申请日：2021-08-26

Applicant: Massachusetts Institute of Technology

Inventor： Xuanhe Zhao ,  Yoonho Kim

IPC: A61B34/00 ,  A61B34/20 ,  B25J9/16 ,  A61B34/30 ,  A61B90/30 ,  A61B18/20 ,  A61B18/00

CPC classification number: A61B34/73 ,  A61B34/20 ,  A61B34/30 ,  A61B34/71 ,  B25J9/1682 ,  A61B18/203 ,  A61B2018/00577 ,  A61B2034/2061 ,  A61B2034/731 ,  A61B2090/306

Abstract: Robotic devices and methods for performing minimally invasive procedures on the vascular system, particularly cerebrovascular and endovascular neurosurgical procedures, where a submillimeter-scale continuum robotic device is configured and adapted for active steering and navigation based on external magnetic actuation. The submillimeter-scale continuum robotic device includes an elongate body having an inner core and an outer shell, where the outer shell is fabricated of an elastomeric material having a plurality of ferromagnetic particles dispersed therein.

公开(公告)号：US11638903B2

公开(公告)日：2023-05-02

申请号：US17068239

申请日：2020-10-12

Applicant: Massachusetts Institute of Technology

Inventor： Omar Labban ,  Grace Goon ,  John H. Lienhard ,  Xuanhe Zhao

IPC: B01D65/02

Abstract: Enhanced cleaning of a fouled membrane is achieved via controlled deformation in a method wherein a feed composition, comprising a solvent and dissolved components, flows into a retentate side of a membrane module. The solvent passes through the membrane from the retentate side to a permeate or draw side of the membrane module while retaining the dissolved components on the membrane. As a foulant accumulates on either side of the membrane, a driving force is generated across the membrane, wherein the membrane responds cyclically by deforming back and forth toward the permeate or draw side and toward the retentate side. The foulant is dislodged from the membrane via mechanical fatigue at the foulant-membrane interface caused by the deformation of the membrane and contact with a spacer in contact with the membrane.