公开(公告)号：US20210086112A1

公开(公告)日：2021-03-25

申请号：US16933158

申请日：2020-07-20

Applicant: Massachusetts Institute of Technology

Inventor： David Brancazio ,  Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  Gerard Capellades Mendez ,  Clemence Neurohr ,  Kersten Rapp

IPC: B01D29/86 ,  A61K31/496 ,  B01D29/05 ,  B01D29/60 ,  B01D35/18

Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.

公开(公告)号：US10702481B2

公开(公告)日：2020-07-07

申请号：US15898010

申请日：2018-02-15

Applicant: Massachusetts Institute of Technology

Inventor： Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  David Brancazio ,  Juan Guillermo Osorio Caicedo

IPC: A61K9/20 ,  A61J3/10 ,  B01F13/10 ,  B30B15/30 ,  B30B11/02 ,  B30B11/08 ,  B29C43/34 ,  A61K31/192 ,  A61K31/5513

Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).

公开(公告)号：US12251651B2

公开(公告)日：2025-03-18

申请号：US18460353

申请日：2023-09-01

Applicant: Massachusetts Institute of Technology

Inventor： David Brancazio ,  Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  Gerard Capellades Mendez ,  Clemence Neurohr ,  Kersten Rapp ,  Naomi Elizabeth Barbara Briggs

IPC: B01D29/86 ,  A61J3/10 ,  A61K31/496 ,  B01D29/05 ,  B01D29/075 ,  B01D29/60 ,  B01D35/18

Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.

公开(公告)号：US11911719B2

公开(公告)日：2024-02-27

申请号：US16933158

申请日：2020-07-20

Applicant: Massachusetts Institute of Technology

Inventor： David Brancazio ,  Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  Gerard Capellades Mendez ,  Clemence Neurohr ,  Kersten Rapp ,  Naomi Elizabeth Barbara Briggs

IPC: B01D29/86 ,  A61K31/496 ,  B01D29/05 ,  B01D29/60 ,  B01D35/18 ,  A61J3/10 ,  B01D29/075

CPC classification number: B01D29/86 ,  A61K31/496 ,  B01D29/05 ,  B01D29/608 ,  B01D35/18 ,  A61J3/10 ,  B01D29/075 ,  B01D2201/204

Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.

公开(公告)号：US11020352B2

公开(公告)日：2021-06-01

申请号：US16883909

申请日：2020-05-26

Applicant: Massachusetts Institute of Technology

Inventor： Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  David Brancazio ,  Juan Guillermo Osorio Caicedo

IPC: A61K9/20 ,  A61J3/10 ,  B01F13/10 ,  B30B15/30 ,  B30B11/02 ,  B29C43/34 ,  B30B11/08 ,  A61K31/192 ,  A61K31/5513

Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).

公开(公告)号：US20180271791A1

公开(公告)日：2018-09-27

申请号：US15898010

申请日：2018-02-15

Applicant: Massachusetts Institute of Technology

Inventor： Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  David Brancazio ,  Juan Guillermo Osorio Caicedo

IPC: A61K9/20 ,  A61K31/192 ,  A61K31/5513 ,  A61J3/10

Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).

公开(公告)号：US20240066443A1

公开(公告)日：2024-02-29

申请号：US18460353

申请日：2023-09-01

Applicant: Massachusetts Institute of Technology

Inventor： David Brancazio ,  Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  Gerard Capellades Mendez ,  Clemence Neurohr ,  Kersten Rapp ,  Naomi Elizabeth Barbara Briggs

IPC: B01D29/86 ,  A61K31/496 ,  B01D29/05 ,  B01D29/60 ,  B01D35/18

CPC classification number: B01D29/86 ,  A61K31/496 ,  B01D29/05 ,  B01D29/608 ,  B01D35/18 ,  B01D29/075

Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.

公开(公告)号：US11786846B2

公开(公告)日：2023-10-17

申请号：US16933158

申请日：2020-07-20

Applicant: Massachusetts Institute of Technology

Inventor： David Brancazio ,  Allan S. Myerson ,  Mohammad A. Azad ,  Gregory J. Hammersmith ,  Gerard Capellades Mendez ,  Clemence Neurohr ,  Kersten Rapp ,  Naomi Elizabeth Barbara Briggs

IPC: B01D29/86 ,  A61K31/496 ,  B01D29/05 ,  B01D29/60 ,  B01D35/18 ,  A61J3/10 ,  B01D29/075

CPC classification number: B01D29/86 ,  A61K31/496 ,  B01D29/05 ,  B01D29/608 ,  B01D35/18 ,  A61J3/10 ,  B01D29/075 ,  B01D2201/204

Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.