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公开(公告)号:US12251651B2
公开(公告)日:2025-03-18
申请号:US18460353
申请日:2023-09-01
Applicant: Massachusetts Institute of Technology
Inventor: David Brancazio , Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , Gerard Capellades Mendez , Clemence Neurohr , Kersten Rapp , Naomi Elizabeth Barbara Briggs
IPC: B01D29/86 , A61J3/10 , A61K31/496 , B01D29/05 , B01D29/075 , B01D29/60 , B01D35/18
Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
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公开(公告)号:US11911719B2
公开(公告)日:2024-02-27
申请号:US16933158
申请日:2020-07-20
Applicant: Massachusetts Institute of Technology
Inventor: David Brancazio , Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , Gerard Capellades Mendez , Clemence Neurohr , Kersten Rapp , Naomi Elizabeth Barbara Briggs
IPC: B01D29/86 , A61K31/496 , B01D29/05 , B01D29/60 , B01D35/18 , A61J3/10 , B01D29/075
CPC classification number: B01D29/86 , A61K31/496 , B01D29/05 , B01D29/608 , B01D35/18 , A61J3/10 , B01D29/075 , B01D2201/204
Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
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公开(公告)号:US11020352B2
公开(公告)日:2021-06-01
申请号:US16883909
申请日:2020-05-26
Applicant: Massachusetts Institute of Technology
Inventor: Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , David Brancazio , Juan Guillermo Osorio Caicedo
IPC: A61K9/20 , A61J3/10 , B01F13/10 , B30B15/30 , B30B11/02 , B29C43/34 , B30B11/08 , A61K31/192 , A61K31/5513
Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
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公开(公告)号:US20180271791A1
公开(公告)日:2018-09-27
申请号:US15898010
申请日:2018-02-15
Applicant: Massachusetts Institute of Technology
Inventor: Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , David Brancazio , Juan Guillermo Osorio Caicedo
IPC: A61K9/20 , A61K31/192 , A61K31/5513 , A61J3/10
Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
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公开(公告)号:US20170354609A1
公开(公告)日:2017-12-14
申请号:US15620568
申请日:2017-06-12
Applicant: Massachusetts Institute of Technology
Inventor: Vibha Puri , Parind Mahendrakumar Desai , Keith D. Jensen , David Brancazio , Eranda Harinath , Alexander Racine Martinez , Jung Hoon Chun , Richard Dean Braatz , Allan S. Myerson , Bernhardt Levy Trout
CPC classification number: A61K9/2893 , A61K9/2013 , A61K9/2018 , A61K9/205 , A61K9/284 , A61K9/2853 , A61K31/343 , B29C45/14819 , B29C45/1615 , B29C45/1671 , B29K2029/04 , B29K2067/04 , B29K2071/02
Abstract: The disclosure describes an injection molding process for coating a tablet core to produce a coated pharmaceutical tablet, wherein the injection-molded coating is substantially continuous (e.g., completely covers the tablet core with no openings), and describes the resulting coated pharmaceutical tablet. The disclosure describes compositions for coatings and tablet cores and equipment suitable for performing the process.
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6.
公开(公告)号:US20240066443A1
公开(公告)日:2024-02-29
申请号:US18460353
申请日:2023-09-01
Applicant: Massachusetts Institute of Technology
Inventor: David Brancazio , Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , Gerard Capellades Mendez , Clemence Neurohr , Kersten Rapp , Naomi Elizabeth Barbara Briggs
IPC: B01D29/86 , A61K31/496 , B01D29/05 , B01D29/60 , B01D35/18
CPC classification number: B01D29/86 , A61K31/496 , B01D29/05 , B01D29/608 , B01D35/18 , B01D29/075
Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
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公开(公告)号:US11786846B2
公开(公告)日:2023-10-17
申请号:US16933158
申请日:2020-07-20
Applicant: Massachusetts Institute of Technology
Inventor: David Brancazio , Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , Gerard Capellades Mendez , Clemence Neurohr , Kersten Rapp , Naomi Elizabeth Barbara Briggs
IPC: B01D29/86 , A61K31/496 , B01D29/05 , B01D29/60 , B01D35/18 , A61J3/10 , B01D29/075
CPC classification number: B01D29/86 , A61K31/496 , B01D29/05 , B01D29/608 , B01D35/18 , A61J3/10 , B01D29/075 , B01D2201/204
Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
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公开(公告)号:US20210086112A1
公开(公告)日:2021-03-25
申请号:US16933158
申请日:2020-07-20
Applicant: Massachusetts Institute of Technology
Inventor: David Brancazio , Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , Gerard Capellades Mendez , Clemence Neurohr , Kersten Rapp
IPC: B01D29/86 , A61K31/496 , B01D29/05 , B01D29/60 , B01D35/18
Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
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公开(公告)号:US10702481B2
公开(公告)日:2020-07-07
申请号:US15898010
申请日:2018-02-15
Applicant: Massachusetts Institute of Technology
Inventor: Allan S. Myerson , Mohammad A. Azad , Gregory J. Hammersmith , David Brancazio , Juan Guillermo Osorio Caicedo
IPC: A61K9/20 , A61J3/10 , B01F13/10 , B30B15/30 , B30B11/02 , B30B11/08 , B29C43/34 , A61K31/192 , A61K31/5513
Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
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