公开(公告)号：US20190160139A1

公开(公告)日：2019-05-30

申请号：US16119135

申请日：2018-08-31

申请人： Massachusetts Institute of Technology ,  The General Hospital Corporation ,  The Brigham and Women's Hospital, Inc.

发明人： Robert S. Langer ,  Carlo Giovanni Traverso ,  Ameya R. Kirtane ,  Daniel Cahill ,  Ganesh Shankar

IPC分类号： A61K38/00 ,  A61K9/00 ,  A61K9/51 ,  A61P35/00 ,  C12Q1/6858 ,  C12Q1/6886 ,  C12N9/04 ,  C12N9/10

摘要： Provided herein are pharmaceutical compositions for local administration of metabolic inhibitors, methods of locally administering such compositions, and rapid diagnostic methods for identifying mutant allele during the course of a surgical procedure.

公开(公告)号：US20210322507A1

公开(公告)日：2021-10-21

申请号：US17363897

申请日：2021-06-30

申请人： Massachusetts Institute of Technology ,  The General Hospital Corporation ,  The Brigham and Women's Hospital, Inc.

发明人： Robert S. Langer ,  Carlo Giovanni Traverso ,  Ameya R. Kirtane ,  Daniel Cahill ,  Ganesh Shankar

IPC分类号： A61K38/00 ,  C12Q1/6886 ,  A61P35/00 ,  A61K47/69 ,  A61K9/00 ,  A61K9/51 ,  C12N9/04 ,  C12N9/10 ,  C12Q1/6858

摘要： Provided herein are pharmaceutical compositions for local administration of metabolic inhibitors, methods of locally administering such compositions, and rapid diagnostic methods for identifying mutant allele during the course of a surgical procedure.