摘要:
A method of isolating 1-�N.sup.2 -((S)-ethoxycarbonyl)-3-phenylpropyl)-N.sup.6 -trifluoroacetyl!-L-lysyl-L-proline (lisinopril (TFA) ethyl ester, LPE). The solvent or solvent mixture used for the extraction is also a main constituent of the solvent or solvent mixture from which the crystallization takes place. High yield as well as good purity of the end product are obtained, without distillation. 1-�N.sup.2 -((S)-ethoxycarbonyl)-3-phenylpropyl)-N.sup.6 -trifluoroacetyl!-L-lysyl-L-proline (lisinopril (TFA) ethyl ester, LPE) is described as a precursor for producing an ACE inhibitor.
摘要:
A method of isolating 1-[N2-((S)-ethoxycarbonyl)-3-phenylpropyl)-N6-trifluoroacetyl]-L-lysyl-L-proline (lisinopril (TFA) ethyl ester, LPE). The solvent or solvent mixture used for the extraction is also a main constituent of the solvent or solvent mixture from which the crystallization takes place. High yield as well as good purity of the end product are obtained, without distillation. 1-[N2-((S)-ethoxycarbonyl)-3-phenylpropyl)-N6-trifluoroacetyl]-L-lysyl-L-proline (lisinopril (TFA) ethyl ester, LPE) is described as a precursor for producing an ACE inhibitor.
摘要:
A method of producing optically active pyrrolidines of the general formula ##STR1## in which R.sup.1 is hydrogen or OH,R.sup.2 is a benzyl group which can have one or more alkyl-, alkoxy- and/or halogen substituents on the aromatic, and* is and/or can be an asymmetric center,by reducing the corresponding, enantiomerically pure pyrrolidinediones using activated alkali boron hydride.
摘要:
A gas bag arrangement for a vehicle occupant restraint system of a motor vehicle. The gas bag arrangement comprising a gas bag package which includes a folded gas bag and a wrapping which at least partly surrounds the folded gas bag, at least one connecting strap for connecting the gas bag to a holding structure of the motor vehicle, wherein the connecting strap is attached to a fastening portion of the gas bag and a deflection device arranged at the wrapping or formed by the wrapping, at which the connecting strap—relative to the condition of the gas bag arrangement as mounted in the vehicle—is deflected in direction of the holding structure. A section of the connecting strap coming from the fastening portion extends up to the deflection device away from the holding structure and at the deflection device again is deflected towards the holding structure.
摘要:
A vehicle occupant restraint system includes an inflatable airbag arranged in a vehicle seat. When the airbag is triggered it at least partially unfolds in the direction of travel on a side of the vehicle seat facing the vehicle interior. The vehicle seat includes a backrest frame extending in a substantially vertical direction in the vehicle seat and substantially aligned in the direction of travel. The airbag is connected to a front end of the backrest frame pointing in the direction of travel.
摘要:
A side airbag device for a vehicle includes an airbag which is deployed in the event of an accident and, in the deployed state, covers a side wall section of the vehicle. In order for the airbag to reliably deploy, provision is made according to embodiments of the invention for the side airbag device to have a deployment control mechanism which deflect the airbag during its deployment around an obstacle situated in a region of a side wall section.
摘要:
A fibrous slurry refiner includes a casing, a rotor secured to a rotor shaft, and first and second pluralities of grinding surfaces. The rotor is disposed within the casing and is rotatable via the rotor shaft. The first plurality of grinding surfaces is secured to the rotor, and the second plurality of grinding surfaces is disposed facing the first plurality of grinding surfaces and fixed in the casing. An inlet plate for each of the plurality of grinding surfaces directs the fibrous slurry toward a set of facing first and second grinding surfaces and imparts a rotary flow to the fibrous slurry.