专利检索 ap:("Maurizio Varrone" OR "Massimiliano Travagli" OR "Giacomo Minetto" OR "Lucia Cesari" OR "Simone Galeazzi" OR "Andrea Caricasole" OR "Antonio Chiumiento" OR "Massimiliano Salerno") AND inv:"Simone Galeazzi" 第 1 页

1.

发明申请
WNT PATHWAY ANTAGONISTS 审中-公开

公开(公告)号：US20140005164A1

公开(公告)日：2014-01-02

申请号：US14004292

申请日：2012-03-23

申请人： Maurizio Varrone , Massimiliano Travagli , Giacomo Minetto , Lucia Cesari , Simone Galeazzi , Andrea Caricasole , Antonio Chiumiento , Massimiliano Salerno

发明人： Maurizio Varrone , Massimiliano Travagli , Giacomo Minetto , Lucia Cesari , Simone Galeazzi , Andrea Caricasole , Antonio Chiumiento , Massimiliano Salerno

IPC分类号： C07D401/12 , C07D471/04 , C07D473/32 , C07D491/10 , C07D235/26 , C07D417/12 , C07D401/08 , C07D491/08 , C07D403/12 , C07D413/14

CPC分类号： C07D401/12 , C07D235/26 , C07D401/08 , C07D401/14 , C07D403/08 , C07D403/12 , C07D403/14 , C07D405/12 , C07D413/08 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D473/32 , C07D491/08 , C07D491/10 , C07D493/10 , C07D498/08

摘要： The present invention relates to novel compounds of formula (I): as herein described and pharmaceutical compositions thereof. The compounds of formula (I) have inhibitory effect on the Wnt pathway and are therefore useful in the preparation of a medicament, in particular for the treatment of cancer.

摘要翻译： 本发明涉及式（I）的新化合物：如本文所述及其药物组合物。式（I）化合物对Wnt途径具有抑制作用，因此可用于制备药物，特别是用于治疗癌症。