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公开(公告)号：US20200306544A1
公开(公告)日：2020-10-01
申请号：US16369948
申请日：2019-03-29
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Aleksandre Sambelashvili , Jeffrey Gillberg , Manfred Justen , Sean Farrell
IPC: A61N1/368 , A61B5/0408
Abstract: Systems, methods, and devices are described herein for evaluation, adjustment, and delivery of adaptive cardiac therapy. The systems, methods, and devices may utilize electrical heterogeneity information to determine and/or select one or more pacing settings and pacing type or configurations for a plurality of different heart rates. The adaptive cardiac therapy may deliver cardiac therapy at selected pacing settings such as, for example, A-V and/or V-V intervals, according to a presently measured heart rate and switch between left ventricular-only or biventricular cardiac pacing therapy also according to the presently measured heart rate.
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公开(公告)号：US20200046984A1
公开(公告)日：2020-02-13
申请号：US16656981
申请日：2019-10-18
Applicant: Medtronic, Inc.
Inventor： Aleksandre Sambelashvili , Thomas J. Mullen , Todd J. Sheldon
Abstract: Cardiac resynchronization therapy (CRT) delivered to a heart of a patient may be adjusted based on detection of a surrogate indication of the intrinsic atrioventricular conduction of the heart. In some examples, the surrogate indication is determined to be a sense event of the first depolarizing ventricle of the heart within a predetermined period of time following the delivery of a fusion pacing stimulus to the later depolarizing ventricle. In some examples, the CRT is switched from a fusion pacing configuration to a biventricular pacing configuration if the surrogate indication is not detected, and the CRT is maintained in a fusion pacing configuration if the surrogate indication is detected.
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公开(公告)号：US11547858B2
公开(公告)日：2023-01-10
申请号：US16369948
申请日：2019-03-29
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Aleksandre Sambelashvili , Jeffrey Gillberg , Manfred Justen , Sean Farrell
Abstract: Systems, methods, and devices are described herein for evaluation, adjustment, and delivery of adaptive cardiac therapy. The systems, methods, and devices may utilize electrical heterogeneity information to determine and/or select one or more pacing settings and pacing type or configurations for a plurality of different heart rates. The adaptive cardiac therapy may deliver cardiac therapy at selected pacing settings such as, for example, A-V and/or V-V intervals, according to a presently measured heart rate and switch between left ventricular-only or biventricular cardiac pacing therapy also according to the presently measured heart rate.
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Patent Agency Ranking
公开(公告)号：US11229795B2
公开(公告)日：2022-01-25
申请号：US16656981
申请日：2019-10-18
Applicant: Medtronic, Inc.
Inventor： Aleksandre Sambelashvili , Thomas J. Mullen , Todd J. Sheldon
Abstract: Cardiac resynchronization therapy (CRT) delivered to a heart of a patient may be adjusted based on detection of a surrogate indication of the intrinsic atrioventricular conduction of the heart. In some examples, the surrogate indication is determined to be a sense event of the first depolarizing ventricle of the heart within a predetermined period of time following the delivery of a fusion pacing stimulus to the later depolarizing ventricle. In some examples, the CRT is switched from a fusion pacing configuration to a biventricular pacing configuration if the surrogate indication is not detected, and the CRT is maintained in a fusion pacing configuration if the surrogate indication is detected.
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5.发明申请公开(公告)号：US20190329046A1
公开(公告)日：2019-10-31
申请号：US15966960
申请日：2018-04-30
Applicant: Medtronic, Inc.
Inventor： Aleksandre Sambelashvili , Yong Cho , Jeffrey Gillberg
Abstract: A method and implantable medical device system for delivering a left ventricular (LV) cardiac pacing therapy via a single-pass coronary sinus lead and sensing far-field cardiac signals via one or more far-field sensing vectors formed between the plurality of electrodes. Beat morphologies corresponding to the far-field cardiac signals are determined, and a beat morphology match between each of the far-field beat morphologies and an intrinsic beat morphology template is determined so that one of loss of LV capture, pseudo fusion and loss of synchrony is determined in response to the determined beat morphology match. One of a loss of capture adjustment, a pseudo fusion adjustment, and a resynchronization adjustment is performed in response to the determined one of loss of LV capture, pseudo fusion and loss of synchrony in response to the determined beat morphology match to generate an adjusted LV cardiac pacing therapy.
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公开(公告)号：US11351383B2
公开(公告)日：2022-06-07
申请号：US15966960
申请日：2018-04-30
Applicant: Medtronic, Inc.
Inventor： Aleksandre Sambelashvili , Yong Cho , Jeffrey Gillberg
Abstract: A method and implantable medical device system for delivering a left ventricular (LV) cardiac pacing therapy via a single-pass coronary sinus lead and sensing far-field cardiac signals via one or more far-field sensing vectors formed between the plurality of electrodes. Beat morphologies corresponding to the far-field cardiac signals are determined, and a beat morphology match between each of the far-field beat morphologies and an intrinsic beat morphology template is determined so that one of loss of LV capture, pseudo fusion and loss of synchrony is determined in response to the determined beat morphology match. One of a loss of capture adjustment, a pseudo fusion adjustment, and a resynchronization adjustment is performed in response to the determined one of loss of LV capture, pseudo fusion and loss of synchrony in response to the determined beat morphology match to generate an adjusted LV cardiac pacing therapy.
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7.发明授权公开(公告)号：US11191969B2
公开(公告)日：2021-12-07
申请号：US15967015
申请日：2018-04-30
Applicant: Medtronic, Inc.
Inventor： Aleksandre Sambelashvili , Yong Cho , Jeffrey Gillberg
Abstract: A method and implantable medical device system for delivering a cardiac pacing therapy that includes suspending delivery of the LV cardiac pacing therapy and sensing far-field cardiac signals via one or more far-field sensing vectors formed between a plurality of electrodes positioned on a single-pass coronary sinus lead. Far-field signal features are determined in response to the sensed far-field cardiac signals, a first offset interval and a second offset interval are determined in response to the determined far-field signal features, and an AV delay of the LV cardiac pacing therapy is adjusted in response to the determined first offset interval and second offset interval. Delivery of the LV cardiac pacing therapy having the adjusted AV delay is subsequently resumed.
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8.发明申请公开(公告)号：US20190329034A1
公开(公告)日：2019-10-31
申请号：US15967015
申请日：2018-04-30
Applicant: Medtronic, Inc.
Inventor： Aleksandre Sambelashvili , Yong Cho , Jeffrey Gillberg
Abstract: A method and implantable medical device system for delivering a cardiac pacing therapy that includes suspending delivery of the LV cardiac pacing therapy and sensing far-field cardiac signals via one or more far-field sensing vectors formed between a plurality of electrodes positioned on a single-pass coronary sinus lead. Far-field signal features are determined in response to the sensed far-field cardiac signals, a first offset interval and a second offset interval are determined in response to the determined far-field signal features, and an AV delay of the LV cardiac pacing therapy is adjusted in response to the determined first offset interval and second offset interval. Delivery of the LV cardiac pacing therapy having the adjusted AV delay is subsequently resumed.
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