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公开(公告)号：US20220257938A1
公开(公告)日：2022-08-18
申请号：US17731462
申请日：2022-04-28
Applicant: Medtronic, Inc.
Inventor： Mark T. STEWART , Brian T. HOWARD
Abstract: A method, system, and device for electroporation. A method for electroporating tissue, the method may include positioning a medical device having a plurality of electrodes proximate an area of tissue, delivering electroporation energy to the plurality of electrodes with an energy generator, receiving data from the plurality of electrodes, determining whether an alert condition is present based upon the data received from the plurality of electrodes, and at least one of cease a delivery of electroporation energy to the plurality of electrodes and prevent the delivery of electroporation energy to the plurality of electrodes when a processing circuitry determines that an alert condition is present.
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公开(公告)号：US20180250508A1
公开(公告)日：2018-09-06
申请号：US15448912
申请日：2017-03-03
Applicant: Medtronic, Inc.
Inventor： Brian T. HOWARD
IPC: A61N1/32 , A61B5/0402 , A61B5/00 , A61B5/053
Abstract: A method of delivering pulsed electrical energy to a target tissue region includes delivering a first therapeutic pulse, the delivering of the first therapeutic pulse includes delivering a first pulse for a first time period, the first pulse having a first voltage amplitude. A second pulse is delivered immediately after the first pulse for a second time period, the second pulse having a second voltage amplitude configured to electroporate the target tissue region, the second time period being less than the first time period. A third pulse is delivered without delay after the second pulse for a third time period, the third pulse having a third voltage amplitude being at least one from the group consisting of substantially the same as the first amplitude, larger than the first amplitude, and less than the first amplitude.
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公开(公告)号：US20180221078A1
公开(公告)日：2018-08-09
申请号：US15427534
申请日：2017-02-08
Applicant: Medtronic, Inc.
Inventor： Brian T. HOWARD , Steven J. FRAASCH , Mark T. STEWART , John VANDANACKER
Abstract: A method of determining a pulsed field ablation waveform parameter for creating a desired lesion characteristic in cardiac tissue. The method of provides an electrosurgical generator configured to deliver electroporation pulses, the generator configured to: load predetermined waveform parameters (yi); load predetermined modeling data (xi); accept entry of a user inputted desired lesion characteristic (ui); and determine at least one corresponding pulsed field ablation waveform parameter based on (ui), (yi); and (xi).
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公开(公告)号：US20200009378A1
公开(公告)日：2020-01-09
申请号：US16573181
申请日：2019-09-17
Applicant: Medtronic, Inc.
Inventor： Mark T. STEWART , Brian T. HOWARD
Abstract: A method, system, and device for electroporation. A system may include a medical device with a plurality of electrodes borne on an expandable element and an energy generator in communication with the electrodes. The energy generator may have processing circuitry configured to selectively deliver electroporation energy to at least one of the electrodes. The processing circuitry may determine whether an alert condition is present and, if so, cease the delivery of electroporation energy to one or more electrodes identified as the cause of the alert condition and/or prevent the delivery of electroporation energy to the one or more electrodes identified as the cause of the alert condition. The energy generator may also be configured to deliver electroporation energy in a sequence of a plurality of energy delivery patterns to enhance lesion formation.
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公开(公告)号：US20190254735A1
公开(公告)日：2019-08-22
申请号：US16263812
申请日：2019-01-31
Applicant: Medtronic, Inc.
Inventor： Mark T. STEWART , Brian T. HOWARD
Abstract: Devices, systems, and methods for more efficiently ablating tissue with pulsed field ablation energy while minimizing collateral injury to non-target tissue. In one embodiment, a system for ablating tissue at a treatment site comprises: an energy delivery device; and a control unit including: a source of impedance-modifying fluid in fluid communication with the energy delivery device; an energy generator in electrical communication with the energy delivery device, the energy generator being configured to transmit energy to the energy delivery device and the energy delivery device being configured to deliver energy to the treatment site; and processing circuitry configured to control delivery of the impedance-modifying fluid from the energy delivery device to the treatment site. In one embodiment, a method for ablating tissue comprises delivering an impedance-modifying fluid to a treatment site and delivering pulsed field ablation energy to the treatment site.
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Patent Agency Ranking
公开(公告)号：US20200155838A1
公开(公告)日：2020-05-21
申请号：US16747767
申请日：2020-01-21
Applicant: Medtronic, Inc.
Inventor： Brian T. HOWARD
IPC: A61N1/32 , A61B18/12 , A61B5/053 , A61B5/00 , A61B5/0402
Abstract: A method of delivering pulsed electrical energy to a target tissue region includes delivering a first therapeutic pulse, the delivering of the first therapeutic pulse includes delivering a first pulse for a first time period, the first pulse having a first voltage amplitude. A second pulse is delivered immediately after the first pulse for a second time period, the second pulse having a second voltage amplitude configured to electroporate the target tissue region, the second time period being less than the first time period. A third pulse is delivered without delay after the second pulse for a third time period, the third pulse having a third voltage amplitude being at least one from the group consisting of substantially the same as the first amplitude, larger than the first amplitude, and less than the first amplitude.
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公开(公告)号：US20190209235A1
公开(公告)日：2019-07-11
申请号：US16242081
申请日：2019-01-08
Applicant: Medtronic, Inc.
Inventor： Mark T. STEWART , Brian T. HOWARD
CPC classification number: A61B18/1492 , A61B5/04085 , A61B5/0538 , A61B18/1206 , A61B2017/00154 , A61B2018/00023 , A61B2018/00083 , A61B2018/00107 , A61B2018/00136 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00839 , A61B2018/00892 , A61B2018/1465 , A61B2018/1497
Abstract: A medical device for directionally focusing energy to a treatment site, the medical device including a shaft having an elongated body defining a proximal portion and a distal portion opposite the proximal portion, the distal portion including at least one electrode having a contact portion and a permeable sheath at least partially surrounding the at least one electrode, the permeable sheath and the at least one electrode defining an insulation cavity, the permeable sheath being impermeable to an insulation material introduced to the insulation cavity from a fluid source configured to be coupled to the shaft.
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公开(公告)号：US20190038171A1
公开(公告)日：2019-02-07
申请号：US15669048
申请日：2017-08-04
Applicant: Medtronic, Inc.
Inventor： Brian T. HOWARD
Abstract: Devices, systems, and methods relating to a low-voltage, pre-treatment pulse routine for evaluating a potential for non-target tissue damage from the delivery of energy, such as electroporation energy to an area of target tissue. In one embodiment, a medical system includes a medical device having a treatment element; and a control unit in communication with the medical device, the control unit being configured to: deliver a low-voltage, pre-treatment pulse routine through the treatment element to an area of target tissue; determine whether the low-voltage, pre-treatment pulse routine has a stimulation effect on an area of non-target tissue; and deliver an ablation energy routine through the treatment element to the area of target tissue when the control unit determines that the low-voltage, pre-treatment pulse routine does not have a stimulation effect on the area of non-target tissue.
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公开(公告)号：US20180214195A1
公开(公告)日：2018-08-02
申请号：US15418217
申请日：2017-01-27
Applicant: Medtronic, Inc.
Inventor： Steven J. FRAASCH , Catherine R. CONDIE , Brian T. HOWARD , Louis JACOB , Paul S. LAM , Trenton J. REHBERGER , Mark T. STEWART , Qin ZHANG
IPC: A61B18/12 , A61B5/0452 , A61B5/0456 , A61B5/042 , A61B5/00 , A61N1/30 , A61B18/14 , H02H3/16 , H02H1/00
Abstract: A system and method for the safe delivery of treatment energy to a patient, which includes verification of system integrity before, during, or after the delivery of treatment energy and provides several mechanisms for rapid termination of the delivery of potentially harmful energy to the patient when a fault condition in the device and/or system is identified. The system may include an energy generator having processing circuitry to determine if there is a fault condition in the system and to automatically terminate a delivery of treatment energy when the processing circuitry determines there is a fault condition. The method may generally include performing a series of pre-checks, synchronizing a treatment energy delivery to the proper segment of the heart's depolarization pattern, configuring the system for treatment energy delivery, delivering the treatment energy, and performing post-treatment evaluation.
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公开(公告)号：US20190223948A1
公开(公告)日：2019-07-25
申请号：US16251807
申请日：2019-01-18
Applicant: Medtronic, Inc.
Inventor： Mark T. STEWART , Brian T. HOWARD
Abstract: A device, system, and method for ablating tissue with pulsed field ablation energy while minimizing stimulation of skeletal muscle and nerves, as well as minimizing damage to non-targeted tissue. Some embodiments provide a device, system, and method for delivering pulsed field ablation energy to tissue from at least one energy delivery electrode on an energy delivery device to at least one energy return electrode, which may be located on the energy delivery device and/or on a sheath or secondary device. The at least one energy delivery electrode has a surface area for the application of energy that is smaller than the surface area for the receipt or return of energy of the at least one energy return electrode.
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