公开(公告)号：US12213879B2

公开(公告)日：2025-02-04

申请号：US18319819

申请日：2023-05-18

Applicant: Medtronic CV Luxembourg S.A.R.L.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

公开(公告)号：US10702379B2

公开(公告)日：2020-07-07

申请号：US15494923

申请日：2017-04-24

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

公开(公告)号：US11690713B2

公开(公告)日：2023-07-04

申请号：US16891301

申请日：2020-06-03

Applicant: Medtronic CV Luxembourg S.A.R.L.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/008 ,  A61F2230/0013 ,  A61F2230/0017 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/0069

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

公开(公告)号：US20140222144A1

公开(公告)日：2014-08-07

申请号：US13757380

申请日：2013-02-01

Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.

Inventor： Carol Eberhardt ,  Gopikrishnan Soundararajan ,  Kenny Dang ,  Hussain Rangwala ,  Mark Torrianni ,  Eric Richardson ,  Kshitija Garde

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2230/008 ,  A61F2250/0069

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.

Abstract translation: 经导管瓣膜假体包括可扩张管状支架，支架内的人工瓣膜，以及耦合到管状支架并围绕管状支架的抗瓣膜泄漏部件。 抗瓣膜泄漏部件包括径向可压缩的环形支架，其是自膨胀材料的正弦图案化环，以及在环形支架上延伸的不可渗透膜。 抗瓣膜泄漏部件具有扩张构造，其中环形支架的至少节段径向地远离管状支架。 或者，抗瓣膜泄漏部件包括多个自膨胀部分和联接到部分的内表面的环形密封元件。 抗瓣膜泄漏部件具有扩张构造，其中段部从径向远离管状支架弯曲，并且环形密封元件位于管状支架的外表面和段的内表面之间。

公开(公告)号：US10973630B2

公开(公告)日：2021-04-13

申请号：US16571456

申请日：2019-09-16

Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.

Inventor： Mark Torrianni ,  Eric Richardson ,  Kshitija Garde

IPC: A61F2/24

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.