公开(公告)号：US12213879B2

公开(公告)日：2025-02-04

申请号：US18319819

申请日：2023-05-18

Applicant: Medtronic CV Luxembourg S.A.R.L.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

公开(公告)号：US20240315839A1

公开(公告)日：2024-09-26

申请号：US18736158

申请日：2024-06-06

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： John Gallagher ,  Niall Duffy ,  Declan Costello ,  Oisin Cooney

IPC: A61F2/24 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966

CPC classification number: A61F2/2427 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/95 ,  A61F2/2418 ,  A61F2002/9505 ,  A61F2002/9534 ,  A61F2002/9583 ,  A61F2002/9665 ,  A61F2230/0095 ,  A61F2230/0097 ,  A61F2250/0003

Abstract: In some embodiments, a medical device delivery system includes a catheter and a retainer. The retainer can be engaged with the medical device to restrain relative movement of the medical device in one or more axial and/or radial directions. A variety of retainers and retainer systems are disclosed, many of which can reliably disengage the medical device from the retainer. Methods for using the medical device delivery system are also described.

公开(公告)号：US12076238B2

公开(公告)日：2024-09-03

申请号：US17844032

申请日：2022-06-19

Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.

Inventor： Than Nguyen ,  Hung Nguyen ,  MyKim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/001 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10S623/90

Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

公开(公告)号：US11622858B2

公开(公告)日：2023-04-11

申请号：US16596937

申请日：2019-10-09

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： Stephen Montgomery ,  Maro Sciacchitano

IPC: A61F2/24 ,  A61B17/00 ,  A61M25/01

Abstract: A system including a self-expanding prosthesis configured to foreshorten during deployment thereof and a delivery device configured to percutaneously deliver the self-expanding prosthesis. The delivery device includes a handle having an actuator thereon, an outer sheath including a proximal end coupled to the handle and a pusher shaft slidingly disposed within the outer sheath. The pusher shaft has a proximal end coupled to the handle and a distal end configured to releasably couple to the self-expanding prosthesis such that the self-expanding prosthesis axially moves therewith. The inner shaft has a distal portion of the inner shaft that is configured to receive a self-expanding prosthesis thereon. The outer sheath and the pusher shaft are configured to simultaneously move in opposing axial directions via actuation of the actuator on the handle to compensate for the foreshortening of the self-expanding prosthesis during deployment.

公开(公告)号：US11284985B2

公开(公告)日：2022-03-29

申请号：US16697965

申请日：2019-11-27

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： Paraic Frisby ,  Niall Duffy

IPC: A61F2/24 ,  A61F2/00 ,  A61F2/95

Abstract: A loading device includes a locking collar assembly including a proximal end, a distal end, and a loading channel formed between the proximal end and the distal end. The device also includes a loading funnel coupled to the distal end of the locking collar assembly at a proximal end of the loading funnel. The loading funnel is configured to store a collapsible medical device in a partially collapsed state within a tapered interior volume of the loading funnel. The tapered interior volume decreases in volume from a distal end of the loading funnel to the proximal end of the loading funnel.

公开(公告)号：US20210177594A1

公开(公告)日：2021-06-17

申请号：US17177984

申请日：2021-02-17

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： Niall Duffy ,  John Gallagher ,  Gerry McCaffrey ,  Noam Miller ,  Glenn Stante

IPC: A61F2/24

Abstract: A medical device delivery system can include a dilator including a tip having a taper in a distal direction, a coupler, and a flap that radially protrudes from the tip. The flap can be configured to bend against a body lumen to cover at least a portion of the delivery system when the dilator is tracked through the body lumen. A medical device delivery system can include a dilator including a tip having a lumen and a coupler having a lumen. The coupler can be configured to securely connect to the tip such that the lumen of the tip is aligned with the lumen of the coupler to allow a guide wire to pass therethrough. Methods for loading a medical device into a delivery catheter are also disclosed.

公开(公告)号：US20200205965A1

公开(公告)日：2020-07-02

申请号：US16816454

申请日：2020-03-12

Applicant: Medtronic CV Luxembourg S.A.R.L.

Inventor： Padraig SAVAGE ,  Joseph CALLOL ,  Alaena DESTEFANO ,  Joshua DWORK ,  Devin GOSAL ,  Karan PUNGA ,  Finn RINNE ,  Billy TAM

IPC: A61F2/24

Abstract: A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.

公开(公告)号：US20170071737A1

公开(公告)日：2017-03-16

申请号：US15361617

申请日：2016-11-28

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： Gregory Scott Kelley

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/95 ,  A61F2002/9665

Abstract: A catheter that comprises a sheath that is connected at opposing ends to concentric tubes that move relative to each other in a manner that alternatively covers and exposes a medical device loaded onto the catheter. A portion of the sheath is arranged so as to invert upon itself so that axial movement of one tube relative to the other simultaneously moves the inversion point over or away from the device, alternatively covering or exposing the device.

Abstract translation: 一种导管，其包括在相对端连接到以可交替地覆盖和暴露加载到导管上的医疗装置的方式相对于彼此移动的同心管的护套。 护套的一部分被布置成自身反转，使得一个管相对于另一管的轴向运动同时使反转点移动或远离该装置，或者替代地覆盖或暴露该装置。

公开(公告)号：US20230028648A1

公开(公告)日：2023-01-26

申请号：US17767758

申请日：2020-10-19

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： Yas NEUBERGER ,  Salvador AVELAR ,  Shahnaz JAVANI ,  Stuart KARI ,  Richard KLEIN

IPC: A61F2/24

Abstract: A transcatheter valve prosthesis includes a stent and a prosthetic valve. The stent is mechanically or balloon expandable. The stent has an inflow portion and an outflow portion. The inflow portion includes a plurality of side openings defined by a plurality of crowns and a plurality of struts. The outflow portion has three circumferentially spaced apart commissure posts. The prosthetic valve is disposed within and secured to at least the outflow portion of the stent. The prosthetic valve is configured to block blood flow in one direction to regulate blood flow through a central lumen of the stent. The commissure posts are configured to flex or bend flex radially inwardly to reduce stresses observed during valve loading and thereby improve or increase tissue durability of the prosthetic valve.

公开(公告)号：US11497604B2

公开(公告)日：2022-11-15

申请号：US16831905

申请日：2020-03-27

Applicant: Medtronic CV Luxembourg S.a.r.l.

Inventor： John Gallagher

IPC: A61F2/24 ,  A61M25/00 ,  A61M25/06

Abstract: A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.