公开(公告)号：US06454999B1

公开(公告)日：2002-09-24

申请号：US09430244

申请日：1999-10-29

申请人： Mehrdad Farhangnia ,  Alex Leynov ,  Joseph Loeffler ,  Alec A. Piplani ,  Greg Potts ,  Christian Skieller

发明人： Mehrdad Farhangnia ,  Alex Leynov ,  Joseph Loeffler ,  Alec A. Piplani ,  Greg Potts ,  Christian Skieller

IPC分类号： A61M114

CPC分类号： F28F21/062 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1025 ,  A61M1/1036 ,  A61M1/1625 ,  A61M1/1629 ,  A61M1/1698 ,  A61M1/262 ,  A61M1/267 ,  A61M2205/366 ,  Y10S261/28

摘要： An integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood is provided that includes a plurality of partitions disposed within or about the fiber bundle assembly to lengthen the flow path of blood passing through the fiber bundle. Alternatively, or in addition, blood flow paths may be lengthened and oxygenation improved by providing internal recirculation paths within the pump/oxygenator, which also advantageously may be used to reduce blood trauma caused by stagnation nearing moving parts and heat build-up.

摘要翻译： 提供了一种具有旋转的中空纤维束组合的集成血液泵/充氧器，其包含含氧化物和泵血液，其包括设置在纤维束组件内或周围的多个隔板，以延长通过纤维束的血液的流动路径。 或者或另外，可以通过在泵/氧合器内提供内部再循环路径来延长血液流动路径并且改善氧合作用，其也可有利地用于减少由运动部件附近的滞留引起的血液创伤和积热。

公开(公告)号：US06503450B1

公开(公告)日：2003-01-07

申请号：US09475467

申请日：1999-12-30

申请人： Thomas A. Afzal ,  Jean-Pierre Dueri ,  Alex Leynov ,  Anthony Makarewicz ,  Alec A. Piplani ,  Greg Potts

发明人： Thomas A. Afzal ,  Jean-Pierre Dueri ,  Alex Leynov ,  Anthony Makarewicz ,  Alec A. Piplani ,  Greg Potts

IPC分类号： A61M114

CPC分类号： F28F21/062 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1025 ,  A61M1/1029 ,  A61M1/1036 ,  A61M1/1625 ,  A61M1/1629 ,  A61M1/1698 ,  A61M1/262 ,  A61M1/267 ,  A61M2205/366

摘要： Improvements to integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood are provided. An inner member arranged along a central axis of the device accelerates blood entering the fiber bundle to reduce microbubble generation and blood trauma. Shearing loads imposed on the fiber elements of the fiber bundle are reduced by the addition of a reinforcement structure, while the gas flow path is configured to reduce flooding and loss of oxygenation efficiency due to occasional rupture of fiber elements.

摘要翻译： 具有提供含氧化合物和泵血液的旋转中空纤维束组件的集成血液泵/充氧器的改进。 沿着装置的中心轴布置的内部构件加速进入纤维束的血液，以减少微泡产生和血液创伤。 施加在纤维束的纤维元件上的剪切载荷通过添加加强结构而减少，而气体流动路径被配置为减少由于纤维元件的偶尔破裂引起的淹水和氧合效率的损失。