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1.发明授权公开(公告)号：US11759510B2
公开(公告)日：2023-09-19
申请号：US17848466
申请日：2022-06-24
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui
IPC分类号： A61K39/09 , A61K47/64 , A61K47/54 , A61P37/04 , A61K39/39 , A61K47/02 , A61K47/22 , C08B37/00 , A61K39/00
CPC分类号： A61K39/092 , A61K39/39 , A61K47/02 , A61K47/22 , A61K47/549 , A61K47/646 , A61K47/6415 , A61P37/04 , C08B37/0003 , A61K2039/55505 , A61K2039/6037 , A61K2039/70
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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2.发明申请公开(公告)号：US20230041441A1
公开(公告)日：2023-02-09
申请号：US17935864
申请日：2022-09-27
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui , Julie Marie Skinner
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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3.发明授权公开(公告)号：US11759511B2
公开(公告)日：2023-09-19
申请号：US17848468
申请日：2022-06-24
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui
IPC分类号： A61K39/09 , A61K47/64 , A61K47/54 , A61P37/04 , A61K39/39 , A61K47/02 , A61K47/22 , C08B37/00 , A61K39/00
CPC分类号： A61K39/092 , A61K39/39 , A61K47/02 , A61K47/22 , A61K47/549 , A61K47/646 , A61K47/6415 , A61P37/04 , C08B37/0003 , A61K2039/55505 , A61K2039/6037 , A61K2039/70
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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4.发明申请公开(公告)号：US20230029424A1
公开(公告)日：2023-01-26
申请号：US17935871
申请日：2022-09-27
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui , Julie Marie Skinner
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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5.发明申请公开(公告)号：US20230075760A1
公开(公告)日：2023-03-09
申请号：US17934379
申请日：2022-09-22
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui , Julie Marie Skinner
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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6.发明申请公开(公告)号：US20220323593A1
公开(公告)日：2022-10-13
申请号：US17848462
申请日：2022-06-24
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui
IPC分类号： A61K47/61 , A61K47/64 , A61P37/04 , A61K39/09 , A61K39/39 , A61K47/02 , A61K47/22 , C08B37/00
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Steptococcus pneumoniae serotypes.
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7.发明申请公开(公告)号：US20220323565A1
公开(公告)日：2022-10-13
申请号：US17848468
申请日：2022-06-24
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui
IPC分类号： A61K39/09 , A61K47/64 , A61K47/54 , A61P37/04 , A61K39/39 , A61K47/02 , A61K47/22 , C08B37/00
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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8.发明申请公开(公告)号：US20220323564A1
公开(公告)日：2022-10-13
申请号：US17848466
申请日：2022-06-24
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui
IPC分类号： A61K39/09 , A61K47/64 , A61K47/54 , A61P37/04 , A61K39/39 , A61K47/02 , A61K47/22 , C08B37/00
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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9.发明授权公开(公告)号：US11964023B2
公开(公告)日：2024-04-23
申请号：US17848462
申请日：2022-06-24
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui
IPC分类号： A61K47/61 , A61K39/09 , A61K39/39 , A61K47/02 , A61K47/22 , A61K47/64 , A61P37/04 , C08B37/00 , A61K39/00
CPC分类号： A61K47/61 , A61K39/092 , A61K39/39 , A61K47/02 , A61K47/22 , A61K47/6415 , A61K47/646 , A61P37/04 , C08B37/006 , A61K2039/55505 , A61K2039/6037 , A61K2039/70
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Steptococcus pneumoniae serotypes.
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10.发明授权公开(公告)号：US11759523B2
公开(公告)日：2023-09-19
申请号：US17848456
申请日：2022-06-24
发明人： Richard J. Porambo , Chitrananda Abeygunawardana , Luwy Kavuka Musey , Michael J. Kosinski , Yadong Adam Cui
IPC分类号： A61K47/61 , A61K47/64 , A61P37/04 , A61K39/09 , A61K39/39 , A61K47/02 , A61K47/22 , C08B37/00 , A61K39/00
CPC分类号： A61K47/61 , A61K39/092 , A61K39/39 , A61K47/02 , A61K47/22 , A61K47/646 , A61K47/6415 , A61P37/04 , C08B37/006 , A61K2039/55505 , A61K2039/6037 , A61K2039/70
摘要： The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Streptococcus pneumoniae serotypes.
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