公开(公告)号：US20220002309A1

公开(公告)日：2022-01-06

申请号：US17287781

申请日：2019-10-23

申请人： Metacrine, Inc.

发明人： Nicholas D. SMITH ,  Andrew R. HUDSON ,  Mi CHEN ,  Johnny Y. NAGASAWA ,  Iriny BOTROUS

IPC分类号： C07D491/107 ,  C07C237/24 ,  C07D309/14 ,  C07D295/185 ,  C07D257/04 ,  C07D241/18 ,  C07D273/01 ,  C07D498/08 ,  C07D307/22 ,  C07D307/93 ,  C07D233/60 ,  C07D205/04 ,  C07D231/12 ,  C07D241/04 ,  C07D239/42 ,  C07D239/34 ,  C07C311/14 ,  A61P1/16

摘要： Described herein are compounds that are semicarbazide-sensitive amine oxidase (SSAO) inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating or preventing a liver disease or condition.