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公开(公告)号：US20220089575A1
公开(公告)日：2022-03-24
申请号：US17538394
申请日：2021-11-30
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Steven P. GOVEK , Johnny Y. NAGASAWA , Karensa L. DOUGLAS , Andiliy G. LAI
IPC: C07D403/12 , C07D417/12 , C07D275/02 , C07D413/12 , C07D417/04 , C07D231/12 , C07D401/12 , C07D277/28 , A61P1/16 , C07D413/14 , C07D417/14 , C07D263/32 , C07D401/14
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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公开(公告)号：US20220002309A1
公开(公告)日：2022-01-06
申请号：US17287781
申请日：2019-10-23
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Andrew R. HUDSON , Mi CHEN , Johnny Y. NAGASAWA , Iriny BOTROUS
IPC: C07D491/107 , C07C237/24 , C07D309/14 , C07D295/185 , C07D257/04 , C07D241/18 , C07D273/01 , C07D498/08 , C07D307/22 , C07D307/93 , C07D233/60 , C07D205/04 , C07D231/12 , C07D241/04 , C07D239/42 , C07D239/34 , C07C311/14 , A61P1/16
Abstract: Described herein are compounds that are semicarbazide-sensitive amine oxidase (SSAO) inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating or preventing a liver disease or condition.
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公开(公告)号：US20220056019A1
公开(公告)日：2022-02-24
申请号：US17276785
申请日：2019-09-17
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Steven P. GOVEK , Johnny Y. NAGASAWA , Andiliy G. LAI , Karensa L. DOUGLAS
IPC: C07D413/14 , C07D401/14 , C07D417/04 , C07D403/12 , C07D401/12 , C07D231/12 , C07D405/14 , C07D413/04 , C07D417/14 , C07D403/14 , C07D409/14
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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公开(公告)号：US20180244606A1
公开(公告)日：2018-08-30
申请号：US15758709
申请日：2016-09-16
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Steven P. GOVEK , Johnny Y. NAGASAWA
IPC: C07C233/54 , A61K45/06 , A61K31/216 , C07C271/28 , A61K31/27 , C07C255/57 , A61K31/277 , C07D309/08 , A61K31/351 , A61K31/337 , C07D305/08 , C07D335/02 , A61K31/382 , C07D205/04 , A61K31/397 , C07D265/30 , A61K31/5375 , C07C323/50 , C07C317/44 , C07D211/94 , A61K31/45 , C07C235/04 , C07C235/40 , C07D211/06 , A61K31/4453 , C07C235/82 , C07D231/12 , A61K31/415 , C07D213/40 , A61K31/4406 , C07D261/08 , A61K31/42 , C07D295/135 , A61K31/402 , C07D231/56 , A61K31/416 , A61K31/404 , C07D209/04 , C07D317/58 , A61K31/36 , C07D295/26 , C07D295/195 , C07D277/28 , A61K31/426 , A61K31/4184 , C07D235/08 , C07D249/18 , A61K31/4192 , C07D239/42 , A61K31/505 , C07D241/20 , A61K31/4965 , C07D237/20 , A61K31/50 , A61P1/16
CPC classification number: C07C233/54 , A61K31/16 , A61K31/216 , A61K31/27 , A61K31/277 , A61K31/337 , A61K31/351 , A61K31/36 , A61K31/382 , A61K31/397 , A61K31/402 , A61K31/404 , A61K31/415 , A61K31/416 , A61K31/4184 , A61K31/4192 , A61K31/42 , A61K31/426 , A61K31/4406 , A61K31/4453 , A61K31/45 , A61K31/4965 , A61K31/50 , A61K31/505 , A61K31/5375 , A61K45/06 , A61P1/16 , C07C233/63 , C07C233/65 , C07C233/81 , C07C233/87 , C07C235/04 , C07C235/16 , C07C235/40 , C07C235/56 , C07C235/64 , C07C235/82 , C07C237/24 , C07C255/57 , C07C255/60 , C07C271/24 , C07C271/28 , C07C311/07 , C07C311/08 , C07C317/32 , C07C317/44 , C07C323/50 , C07C323/61 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/16 , C07C2602/42 , C07C2603/74 , C07D205/04 , C07D209/04 , C07D211/06 , C07D211/62 , C07D211/76 , C07D211/94 , C07D211/96 , C07D213/40 , C07D231/12 , C07D231/56 , C07D235/04 , C07D235/08 , C07D237/20 , C07D239/42 , C07D241/20 , C07D249/18 , C07D261/08 , C07D265/30 , C07D277/28 , C07D295/088 , C07D295/135 , C07D295/195 , C07D295/26 , C07D305/08 , C07D309/08 , C07D317/58 , C07D319/12 , C07D335/02 , A61K2300/00
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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Patent Agency Ranking
公开(公告)号：US20220081390A1
公开(公告)日：2022-03-17
申请号：US17532618
申请日：2021-11-22
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Steven P. GOVEK , Johnny Y. NAGASAWA
IPC: C07C233/80 , C07D333/32 , C07D239/34 , C07D241/18 , C07D263/32 , C07D205/04 , C07D207/27 , C07D275/03 , C07D277/34 , C07D213/65 , A61K45/06 , C07D207/12 , C07D213/75 , C07D207/08 , C07D213/68 , C07D211/42 , C07D211/46 , C07D213/40 , C07D213/64 , C07D213/80 , C07C271/20 , C07C233/63 , C07C237/22 , C07C237/42 , C07C233/59 , C07C233/62 , A61K31/167 , A61K31/216 , A61K31/381 , A61K31/397 , A61K31/40 , A61K31/4015 , A61K31/421 , A61K31/425 , A61K31/426 , A61K31/4418 , A61K31/445 , A61K31/4965 , A61K31/505 , C07D207/24 , C07D211/94
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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公开(公告)号：US20210300875A1
公开(公告)日：2021-09-30
申请号：US17152548
申请日：2021-01-19
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Steven P. GOVEK , Johnny Y. NAGASAWA
IPC: C07D231/12 , A61P1/16 , A61P1/00 , A61K9/00 , A61K9/06 , A61K9/20 , A61K9/48 , C07D401/04 , C07D401/14 , C07D403/12 , C07D405/12 , C07D471/04
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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公开(公告)号：US20180282263A1
公开(公告)日：2018-10-04
申请号：US15758707
申请日：2016-09-16
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Steven P. GOVEK , Johnny Y. NAGASAWA
IPC: C07C233/80 , C07D213/65 , A61K31/4418 , A61K45/06 , A61K31/167 , C07D207/27 , A61K31/4015 , A61K31/216 , C07D263/32 , A61K31/421 , C07D277/34 , A61K31/426 , C07D333/32 , A61K31/381 , C07D239/34 , A61K31/505 , C07D241/18 , A61K31/4965 , C07D275/03 , A61K31/425 , C07D205/04 , A61K31/397 , C07D207/24 , A61K31/40 , C07D211/94 , A61K31/445
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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公开(公告)号：US20210032195A1
公开(公告)日：2021-02-04
申请号：US16872985
申请日：2020-05-12
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Steven P. GOVEK , Johnny Y. NAGASAWA
IPC: C07C233/80 , C07D333/32 , C07D239/34 , C07D241/18 , C07D263/32 , C07D205/04 , C07D207/27 , C07D275/03 , C07D277/34 , C07D213/65 , A61K45/06 , C07D207/12 , C07D213/75 , C07D207/08 , C07D213/68 , C07D211/42 , C07D211/46 , C07D213/40 , C07D213/64 , C07D213/80 , C07C271/20 , C07C233/63 , C07C237/22 , C07C237/42 , C07C233/59 , C07C233/62 , A61K31/167 , A61K31/216 , A61K31/381 , A61K31/397 , A61K31/40 , A61K31/4015 , A61K31/421 , A61K31/425 , A61K31/426 , A61K31/4418 , A61K31/445 , A61K31/4965 , A61K31/505 , C07D207/24 , C07D211/94
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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公开(公告)号：US20200290973A1
公开(公告)日：2020-09-17
申请号：US16886642
申请日：2020-05-28
Applicant: Metacrine, Inc.
Inventor： Nicholas D. SMITH , Stephen P. GOVEK , Johnny Y. NAGASAWA
IPC: C07D231/12 , A61P1/16 , A61P1/00 , A61K9/00 , A61K9/06 , A61K9/20 , A61K9/48 , C07D401/04 , C07D401/14 , C07D403/12 , C07D405/12 , C07D471/04
Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
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