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公开(公告)号：US08906084B2
公开(公告)日：2014-12-09
申请号：US12684074
申请日：2010-01-07
CPC分类号： A61F2/958 , A61B17/12118 , A61B17/12136 , A61B17/12195 , A61B2017/1205 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/067 , A61F2002/077 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/005 , A61F2250/0003 , A61M2025/0002
摘要： Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
摘要翻译： 实施例提供了使用填充有可固化介质的填充结构来治疗动脉瘤的方法和系统。 方法的一个实施例包括将至少一个双壁填充结构定位在动脉瘤上并用填充介质填充结构，使得外壁符合动脉瘤的内部，并且内壁形成大致管状的内腔 提供血流量。 管腔在填充时和/或填充后用气囊或其他可扩张装置支撑。 监测结构内的压力和/或在结构的外壁和动脉瘤壁之间的空间中的压力，并且响应于压力控制介质流入结构的流动。 压力也可用于确定灌装终点。 当腔保持气球支撑时，介质硬化。 培养基硬化后，取出球囊。
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2.发明授权Graft systems having filling structures supported by scaffolds and methods for their use 有权具有由支架支撑的填充结构的移植系统及其使用方法公开(公告)号：US08870941B2
公开(公告)日：2014-10-28
申请号：US13285897
申请日：2011-10-31
CPC分类号： A61F2/844 , A61F2/07 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/077 , A61F2230/0034 , A61F2250/0003 , A61F2250/0069
摘要： Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.
摘要翻译： 通过在动脉瘤内填充至少一个具有可固化培养基的双壁填充结构来治疗动脉瘤。 填充结构可以在气囊展开机构上传送，以形成和打开通过其中的管状流明。 将脚手架放置在管状内腔中，以帮助保持形状，将填充结构锚定在适当位置，并且提供进入和离开管状内腔的改善的血流过渡。
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3.发明授权Graft systems having filling structures supported by scaffolds and methods for their use 有权具有由支架支撑的填充结构的移植系统及其使用方法公开(公告)号：US08048145B2
公开(公告)日：2011-11-01
申请号：US11413460
申请日：2006-04-28
IPC分类号： A61F2/06
CPC分类号： A61F2/844 , A61F2/07 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/077 , A61F2230/0034 , A61F2250/0003 , A61F2250/0069
摘要： Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.
摘要翻译： 通过在动脉瘤内填充至少一个具有可固化培养基的双壁填充结构来治疗动脉瘤。 填充结构可以在气囊展开机构上传送，以形成和打开通过其中的管状流明。 将脚手架放置在管状内腔中，以帮助保持形状，将填充结构锚定在适当位置，并且提供进入和离开管状内腔的改善的血流过渡。
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公开(公告)号：US20090319029A1
公开(公告)日：2009-12-24
申请号：US12478208
申请日：2009-06-04
申请人： Michael A. Evans , Ivan Tzvetanov , Steven L. Herbowy , Raj P. Ganpath , Amy Lee , Anant Kumar , Gwendolyn A. Watanabe , K.T. Venkateswara Rao
发明人： Michael A. Evans , Ivan Tzvetanov , Steven L. Herbowy , Raj P. Ganpath , Amy Lee , Anant Kumar , Gwendolyn A. Watanabe , K.T. Venkateswara Rao
CPC分类号： A61F2/954 , A61F2/07 , A61F2/82 , A61F2/89 , A61F2/90 , A61F2/958 , A61F2002/067 , A61F2002/077 , A61F2220/0058 , A61F2220/0075 , A61F2230/0034
摘要： A system for treating an aneurysm in a blood vessel comprises a docking scaffold having with upstream and downstream ends, and a central passageway therebetween. The upstream end engages the blood vessel upstream of the aneurysm. A portion of a first and second scaffolds are slidably received in the central passageway such that an outside surface of the first and second scaffolds engage an inside surface of the docking scaffold. A double-walled filling structure has outer and inner walls and the filling structure is adapted to be filled with a hardenable fluid filling medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow therethrough. The double-walled filling structure is coupled with at least one of the first and second leg scaffolds in expanded configuration.
摘要翻译： 用于治疗血管中的动脉瘤的系统包括具有上游和下游端的停放构架以及它们之间的中心通路。 上游端接合动脉瘤上游的血管。 第一和第二支架的一部分可滑动地容纳在中央通道中，使得第一和第二支架的外表面接合对接支架的内表面。 双壁填充结构具有外壁和内壁，并且填充结构适于填充可硬化流体填充介质，使得外壁符合动脉瘤的内表面，并且内壁形成基本上管状的腔，以提供 血流通过的路径。 双壁填充结构与第一和第二腿支架中的至少一个以扩展构型联接。
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5.发明申请Graft Systems Having Filling Structures Supported by Scaffolds and Methods for Their Use 有权具有由支架支撑的填充结构的移植系统及其使用方法公开(公告)号：US20120046684A1
公开(公告)日：2012-02-23
申请号：US13285897
申请日：2011-10-31
IPC分类号： A61M29/00
CPC分类号： A61F2/844 , A61F2/07 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/077 , A61F2230/0034 , A61F2250/0003 , A61F2250/0069
摘要： Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.
摘要翻译： 通过在动脉瘤内填充至少一个具有可固化培养基的双壁填充结构来治疗动脉瘤。 填充结构可以在气囊展开机构上传送，以形成和打开通过其中的管状流明。 将脚手架放置在管状内腔中，以帮助保持形状，将填充结构锚定在适当位置，并且提供进入和离开管状内腔的改善的血流过渡。
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公开(公告)号：US20100106087A1
公开(公告)日：2010-04-29
申请号：US12684074
申请日：2010-01-07
IPC分类号： A61M29/00
CPC分类号： A61F2/958 , A61B17/12118 , A61B17/12136 , A61B17/12195 , A61B2017/1205 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/067 , A61F2002/077 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/005 , A61F2250/0003 , A61M2025/0002
摘要： Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
摘要翻译： 实施例提供了使用填充有可固化介质的填充结构来治疗动脉瘤的方法和系统。 方法的一个实施例包括将至少一个双壁填充结构定位在动脉瘤上并用填充介质填充结构，使得外壁符合动脉瘤的内部，并且内壁形成大致管状的内腔 提供血流量。 管腔在填充时和/或填充后用气囊或其他可扩张装置支撑。 监测结构内的压力和/或在结构的外壁和动脉瘤壁之间的空间中的压力，并且响应于压力控制介质流入结构的流动。 压力也可用于确定灌装终点。 当腔保持气球支撑时，介质硬化。 培养基硬化后，取出球囊。
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公开(公告)号：US07666220B2
公开(公告)日：2010-02-23
申请号：US11482503
申请日：2006-07-07
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61B17/12118 , A61B17/12136 , A61B17/12195 , A61B2017/1205 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/067 , A61F2002/077 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/005 , A61F2250/0003 , A61M2025/0002
摘要： Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
摘要翻译： 实施例提供了使用填充有可固化介质的填充结构来治疗动脉瘤的方法和系统。 方法的一个实施例包括将至少一个双壁填充结构定位在动脉瘤上并用填充介质填充结构，使得外壁符合动脉瘤的内部，并且内壁形成大致管状的内腔 提供血流量。 管腔在填充时和/或填充后用气囊或其他可扩张装置支撑。 监测结构内的压力和/或在结构的外壁和动脉瘤壁之间的空间中的压力，并且响应于压力控制介质流入结构的流动。 压力也可用于确定灌装终点。 当腔保持气球支撑时，介质硬化。 培养基硬化后，取出球囊。
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公开(公告)号：US08182525B2
公开(公告)日：2012-05-22
申请号：US12421297
申请日：2009-04-09
申请人： Steven L. Herbowy , Matthew R. Hellewell , K. T. Venkateswara Rao , Michael A. Evans , Thomas Howell , Gwendolyn A. Watanabe , Bhupendra Shah , James McKinley
发明人： Steven L. Herbowy , Matthew R. Hellewell , K. T. Venkateswara Rao , Michael A. Evans , Thomas Howell , Gwendolyn A. Watanabe , Bhupendra Shah , James McKinley
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2002/075 , A61F2002/077 , A61F2230/0034 , A61F2250/0003
摘要： Aneurysms are treated by filling a double-walled filling structure with a curable medium. The structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. The filling structures are preferably used in pairs for providing flow into the iliac arteries when treating abdominal aortic aneurysm.
摘要翻译： 通过用可固化培养基填充双壁填充结构来处理动脉瘤。 结构可以在气囊展开机构上传送，以便通过其形成和打开管状流明。 填充结构优选成对使用，以在治疗腹主动脉瘤时提供流入髂动脉的流体。
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9.发明授权Mechanical pump for removal of fragmented matter and methods of manufacture and use 有权用于去除碎片物质的机械泵及其制造和使用方法公开(公告)号：US08277470B2
公开(公告)日：2012-10-02
申请号：US13278210
申请日：2011-10-21
申请人： Denise M. Demarais , Stephen A. Leeflang , Michael A. Evans , Gwendolyn A. Watanabe , John C. Tanner, III , Christian S. Eversull
发明人： Denise M. Demarais , Stephen A. Leeflang , Michael A. Evans , Gwendolyn A. Watanabe , John C. Tanner, III , Christian S. Eversull
IPC分类号： A61B17/22
CPC分类号： A61M25/0023 , A61B17/320725 , A61B2017/00685 , A61B2017/320775 , A61M29/02
摘要： Material transport catheters and methods for their use rely on rotation of an impeller within a catheter body and a clearing element for preventing buildup of materials at the opening of the catheter body. The impeller preferably comprises an inner tube or shaft having a helical rotor formed over an outer surface thereof. The clearing element may comprise a free end of a structure near the distal end of the catheter body for disrupting clot, wherein the free end of the structure extends into the distal opening of the catheter body to break up materials as the impeller is rotated. Alternatively, the clearing element may comprise a cutting member disposed at the distal opening of the catheter body.
摘要翻译： 材料输送导管及其使用方法依赖于导管主体内的叶轮的旋转和用于防止材料在导管体开口处积累的清除元件。 叶轮优选地包括在其外表面上形成有螺旋转子的内管或轴。 清除元件可以包括靠近导管主体的远端的结构的自由端，用于破坏凝块，其中结构的自由端延伸到导管主体的远端开口以在叶轮旋转时分解材料。 或者，清除元件可以包括设置在导管主体的远端开口处的切割构件。
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10.发明授权Apparatus and methods for placement and repositioning of intraluminal prostheses 有权用于放置和重新定位腔内假体的装置和方法公开(公告)号：US06350278B1
公开(公告)日：2002-02-26
申请号：US09420618
申请日：1999-10-18
申请人： Jay A. Lenker , Kirsten Freislinger , Michael A. Evans , Gwendolyn A. Watanabe , Timothy J. Ryan , Christopher K. Zarins , Richard O. Murphy
发明人： Jay A. Lenker , Kirsten Freislinger , Michael A. Evans , Gwendolyn A. Watanabe , Timothy J. Ryan , Christopher K. Zarins , Richard O. Murphy
IPC分类号： A61F200
CPC分类号： A61F2/07 , A61F2/0095 , A61F2/848 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/966 , A61F2/97 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/826 , A61F2002/91541 , A61F2002/9511 , A61F2002/9522 , A61F2002/9534 , A61F2002/9665 , A61F2210/0019 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2240/001 , A61F2250/0098
摘要： A delivery catheter for a radially compressible tubular prosthesis comprises an elongate shaft slidably received within an elongate sheath. The prosthesis is carried over the distal end of the shaft where it is contained in a radially compressed configuration by the sheath. After introducing the catheter to a desired target location within a body lumen, the prosthesis may be released by proximally retracting the sheath. The prosthesis will remain anchored to the shaft during at least part of the release procedure, permitting the user to recapture the prosthesis by distally advancing the sheath.
摘要翻译： 用于可径向压缩的管状假体的输送导管包括可细长的轴，该细长轴可滑动地容纳在细长护套内。 假体被承载在轴的远端上，在该远端处，护套以径向压缩的形式容纳在其中。 在将导管引入体腔内的期望的目标位置之后，假体可以通过近端缩回护套来释放。 在至少部分释放过程期间，假体将保持锚固到轴上，允许使用者通过远侧推进护套来重新捕获假体。
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