公开(公告)号：US20080003292A1

公开(公告)日：2008-01-03

申请号：US11675643

申请日：2007-02-16

Applicant: Michael AHLERS ,  Conrad COESTER ,  Klaus ZWIOREK ,  Jan ZILLIES

Inventor： Michael AHLERS ,  Conrad COESTER ,  Klaus ZWIOREK ,  Jan ZILLIES

IPC: A61K9/14 ,  A61K38/02 ,  A61K9/51 ,  B01D21/26 ,  B32B27/02

CPC classification number: A61K9/5169 ,  A61K9/5192 ,  B82Y5/00

Abstract: Nanoparticles are disclosed, consisting essentially of an aqueous gelatin gel, wherein the average diameter of the nanoparticles is at the most 350 nm, the polydispersity index of the nanoparticles is less than or equal to 0.15 and wherein a gelatin is used as starting material for the production process. A process for the production of these nanoparticles is also disclosed.

Abstract translation: 公开了纳米颗粒，其基本上由水性明胶凝胶组成，其中纳米颗粒的平均直径为最多350nm，纳米颗粒的多分散指数小于或等于0.15，并且其中使用明胶作为 生产过程。 还公开了制备这些纳米颗粒的方法。

公开(公告)号：US20070077274A1

公开(公告)日：2007-04-05

申请号：US11555295

申请日：2006-11-01

Applicant: Michael AHLERS

Inventor： Michael AHLERS

IPC: A61K38/39 ,  A61K35/30 ,  C08G63/91 ,  C08G63/48

CPC classification number: C08H1/06 ,  A61L27/222 ,  A61L27/3804 ,  A61L27/3817 ,  A61L27/3852 ,  A61L27/58 ,  C08J3/244 ,  C08J9/30 ,  C08J9/38 ,  C08J2201/024 ,  C08J2207/10 ,  C08J2389/06 ,  C08K5/0016 ,  C08K5/0025 ,  C08K5/053 ,  C08L89/06 ,  C12N5/0068 ,  C12N2533/54

Abstract: A method for producing shaped bodies based on crosslinked gelatin, which may be used as carrier material for tissue implants and have an individually adjustable degradation time, is disclosed, comrising: a) preparing an aqueous gelatin solution; b) partially crosslinking the dissolved gelatin; c) producing a shaped body starting off from the gelatin solution with the partially crosslinked gelatin; and d) crosslinking the gelatin contained in the shaped body.

Abstract translation: 公开了一种用于生产基于交联明胶的成形体的方法，其可用作组织植入物的载体材料并具有单独调节的降解时间，其包括：a）制备明胶水溶液; b）部分交联溶解的明胶; c）用部分交联的明胶从明胶溶液中制备成形体; 和d）使包含在成形体中的明胶交联。