Fluorescently tagged ligands
    1.
    发明申请

    公开(公告)号:US20060211045A1

    公开(公告)日:2006-09-21

    申请号:US10551475

    申请日:2004-03-31

    IPC分类号: C40B40/04 C40B40/10

    摘要: Library comprising a plurality of tagged non-peptide ligands of formula I (LigJL)mL(JTTag)m(JTL(JLLig)m)p including and salts thereof comprising one or a plurality of same or different ligand moieties Lig each linked to a one or a plurality of same or different tag moieties Tag via same or different linker moieties L and same or different linking site or linking functionality JT and JL wherein Lig comprises a GPCR ligand, an inhibitor of an intracellular enzyme or a substrate or inhibitor of a drug transporter; L is a single bond or is any linking moiety selected from a heteroatom such as N, O, S, P, branched or straight chain saturated or unsaturated, optionally heteroatom containing, C1-600 hydrocarbyl and combinations thereof, which may be monomeric, oligomeric having oligomeric repeat of 2 to 30 or polymeric having polymeric repeat in excess of 30 up to 300; Tag is any known or novel tagging substrate; m are each independently selected from a whole number integer from 1 to 3; p is 0 to 3 characterised in that linking is at same or different linking sites in compounds comprising different Lig, JL, L JT and/or -Tag and is at different linking sites in compounds comprising same Lig, JL, L JT and/or -Tag; process for the preparation thereof; process for the preparation of a library compound of formula I or a precursor of formula IV; method for selecting a compound of formula I from a library thereof; compound of formula I associated with information relating to its pharmacological properties; a novel compound of formula I or precursor of formula IV; uses thereof; methods for binding or inhibition therewith; use of a fluorescent target therewith; a modified cell surface GPCR and cells expressing the same; and a kit comprising a compound of formula I and a target therefor.

    Preventing loss of traced information in a data processing apparatus
    2.
    发明申请
    Preventing loss of traced information in a data processing apparatus 有权
    防止在数据处理设备中丢失跟踪信息

    公开(公告)号:US20070050600A1

    公开(公告)日:2007-03-01

    申请号:US11205310

    申请日:2005-08-17

    IPC分类号: G06F9/30

    摘要: Techniques for preventing the loss of trace information being transmitted via trace infrastructure are disclosed. A data processing apparatus for processing instructions is provided. The data processing apparatus comprises: decode/issue logic operable to receive and decode an instruction to be processed by the data processing apparatus and to determine when to issue a decoded instructions for execution by execution logic; execution logic operable to execute the decoded instructions; interface logic selectively operable to receive trace information relating to the state of the data processing apparatus generated in response to execution of the decoded instructions for transmission to trace monitoring infrastructure; and throttle logic operable to predict whether issuing the decoded instruction to the execution logic for execution would be likely to cause the trace information to be transmitted to said trace monitoring infrastructure to exceed a capacity of said trace monitoring infrastructure and, if so, to prevent the decode/issue logic from issuing the decoded instruction to the execution logic. Accordingly, the throttle logic reviews each instruction to be executed and predicts whether issuing that instruction at that time will or is likely to cause the capacity to be exceeded. In the event that the throttle logic determines that the capacity is likely to be exceeded, the instruction is prevented from being issued to the execution logic which reduces the likelihood that any state information is lost.

    摘要翻译: 公开了用于防止通过迹线基础设施传输的跟踪信息丢失的技术。 提供了一种处理指令的数据处理装置。 数据处理装置包括:解码/发布逻辑,可操作以接收和解码由数据处理装置处理的指令,并确定何时发出经执行逻辑执行的解码指令; 执行逻辑,用于执行解码指令; 接口逻辑选择性地可操作以接收与响应于解码指令的执行而生成的数据处理设备的状态相关的跟踪信息,以便传输到跟踪监视基础设施; 并且可操作以用于预测是否向执行逻辑发出解码指令以进行执行的油门逻辑可能导致跟踪信息被发送到所述跟踪监视基础设施以超过所述跟踪监视基础设施的容量,如果是,则阻止 解码/发布逻辑从解码指令发出到执行逻辑。 因此,节气门逻辑检查要执行的每个指令,并且预测当时是否发出该指令将或可能导致超过容量。 在节气门逻辑确定容量可能被超过的情况下,防止指令被发送到执行逻辑,这减少了任何状态信息丢失的可能性。

    RECONFIGURABLE PARTITION FOR COMPARTMENTALISING A SPACE WITHIN A VEHICLE
    4.
    发明申请
    RECONFIGURABLE PARTITION FOR COMPARTMENTALISING A SPACE WITHIN A VEHICLE 审中-公开
    用于分配车辆中的空间的可重新分配

    公开(公告)号:US20140119863A1

    公开(公告)日:2014-05-01

    申请号:US14118020

    申请日:2012-05-17

    IPC分类号: B60P1/43

    摘要: A reconfigurable vehicle partition for compartmentalising a space within a vehicle is disclosed. The partition comprises a frame which is arranged to extend within an interior of the vehicle and which is arranged to support a gate, the gate comprising a plurality of pivotally interconnected panels which are reconfigurable between a folded gate configuration and an unfolded gate configuration. The gate is arranged to pivot with respect to the frame between a closed configuration in which the gate extends substantially within the frame to partition the vehicle, and an open configuration, in which the gate extends out of the plane of the frame. In the closed configuration, the gate is arranged to extend across the frame in a substantially folded configuration, and in the open configuration the gate is arranged to extend out of the plane of the frame in the unfolded configuration to provide a ramp access into and out from the vehicle.

    摘要翻译: 公开了一种用于区分车辆内的空间的可重构车辆隔板。 隔板包括框架,该框架布置成在车辆内部延伸并且被布置成支撑门,该门包括多个可枢转地互连的面板,其可在折叠门构型和未折叠门构型之间重构。 门被布置成相对于框架枢转,在闭合构型之间,其中门基本上在框架内延伸以分隔车辆;以及打开构型,其中门延伸出框架的平面。 在闭合配置中,门被布置成以基本上折叠的构造延伸穿过框架,并且在打开构造中,门布置成在展开构型中延伸出框架的平面以提供斜坡进入和退出 从车上。

    Image generator
    5.
    发明授权
    Image generator 有权
    图像生成器

    公开(公告)号:US08115780B2

    公开(公告)日:2012-02-14

    申请号:US11655051

    申请日:2007-01-18

    IPC分类号: G09G5/00

    摘要: A system and method for generating an image on a display. The display includes a plurality of pixels from a vector description of a scene. The data is sampled from the vector description to provide data samples at locations defined in relation to the pixels. For example, the locations may include a first and second locations at the edges of the pixels, a third location at the corner of the pixels and a fourth location at the center of the pixels. The data samples are stored in a buffer and processed for each of the pixels to give an averaged data value. The image is then generated the image on the display by applying the averaged data value to each of the pixels. The calculation of the weighted averaged color value is repeated for each of the fragments in the buffer until all of the samples have been averaged.

    摘要翻译: 一种用于在显示器上生成图像的系统和方法。 显示器包括来自场景的向量描述的多个像素。 从矢量描述中采样数据,以在与像素相关的位置定义的位置提供数据样本。 例如,位置可以包括在像素的边缘处的第一和第二位置,在像素的角落处的第三位置和在像素的中心处的第四位置。 将数据样本存储在缓冲器中并针对每个像素进行处理以给出平均数据值。 然后,通过将平均数据值应用于每个像素,在图像上生成图像。 对缓冲器中的每个片段重复加权平均颜色值的计算,直到所有样本已经被平均。

    Performance of a data processing apparatus
    7.
    发明申请
    Performance of a data processing apparatus 审中-公开
    数据处理装置的性能

    公开(公告)号:US20070043930A1

    公开(公告)日:2007-02-22

    申请号:US11204399

    申请日:2005-08-16

    IPC分类号: G06F9/30

    摘要: Techniques for improving the performance of a data processing apparatus are disclosed. A data processing apparatus operable to process instructions and operable to determine, prior to each instruction being issued for execution, when resources associated with that instruction are predicted to be available for use by succeeding instructions is provided. The data processing apparatus comprises scoreboard logic operable to store an indication of when resources associated with an instruction to be issued are predicted to be available for use by succeeding instructions; issue logic operable to determine, by reference to the scoreboard logic, when the instruction can be issued for execution, the issue logic being further operable in the case that the instruction falls within a class of instructions which have been designated as instructions for which it is uncertain when resources associated with those instructions will be available for use by succeeding instructions, to prevent succeeding instructions from issuing until all preceding instructions have been executed; and inhibit override logic operable to detect when the instruction to be issued falls within a sub-class of instructions, to review all preceding instructions and, in the event that the they all fall within the sub-class of instructions, to cause the issue logic to enable the succeeding instruction to be issued for execution even when all preceding instructions have not been completed. Enabling the succeeding instruction to be issued without first draining all the preceding instructions reduces the latency period experienced prior to that instruction being issued. It will be appreciated that this approach can significantly improve the performance of the data processing apparatus.

    摘要翻译: 公开了一种用于提高数据处理装置的性能的技术。 一种数据处理装置,可操作以处理指令并且可操作以提供在执行每个指令之前,当与该指令相关联的资源被预测为可供随后的指令使用时。 数据处理装置包括记分板逻辑,其可操作以存储与被发布的指令相关联的资源被预测为可以由后续指令使用的指示; 发出逻辑可操作以通过参考记分板逻辑来确定何时可以发出指令以执行,所述发出逻辑在所述指令落入已被指定为其指令的指令类别的情况下可进一步操作 当与这些指令相关联的资源将可以通过后续指令使用时,不确定,以防止后续指令发出,直到所有先前的指令被执行; 并且禁止超控逻辑可操作以检测什么时候要发出的指令落在指令的子类别内,以检查所有先前的指令,并且在它们都落入指令的子类别的情况下导致发出逻辑 以便即使所有先前的指令尚未完成,也可以执行后续指令以执行。 在不首先排除所有前述指令的情况下启用后续指令将减少发出该指令之前经历的等待时间。 应当理解,该方法可以显着地提高数据处理装置的性能。

    Instruction issue control within a superscalar processor
    8.
    发明申请
    Instruction issue control within a superscalar processor 有权
    超标量处理器中的指令问题控制

    公开(公告)号:US20060271768A1

    公开(公告)日:2006-11-30

    申请号:US11137792

    申请日:2005-05-26

    IPC分类号: G06F9/30

    CPC分类号: G06F9/3836 G06F9/3828

    摘要: A data processing system including multiple execution pipelines each having multiple execution stages E1, E2, E3 may have instructions issued together in parallel despite a data dependency therebetween if it is detected that the result operand value for the older instruction will be generated in an execution stage prior to an execution stage which requires that result operand value as an input operand value to the younger instruction and accordingly cross-forwarding of the operand value is possible between the execution pipelines to resolve the data dependency.

    摘要翻译: 包括具有多个执行阶段E 1,E 2,E 3的多个执行流水线的数据处理系统可以具有并行发布的指令,尽管如果检测到较旧指令的结果操作数值将被生成 在执行阶段之前的执行阶段,其需要将结果操作数值作为较年轻指令的输入操作数值,并且因此在执行流水线之间交叉转换操作数值以解决数据依赖性。

    Provision of debug via a separate ring bus in a data processing apparatus
    9.
    发明申请
    Provision of debug via a separate ring bus in a data processing apparatus 有权
    通过数据处理设备中的单独的环形总线提供调试

    公开(公告)号:US20060218448A1

    公开(公告)日:2006-09-28

    申请号:US11085598

    申请日:2005-03-22

    IPC分类号: G06F11/00

    摘要: A data processing apparatus is provided having a plurality of functional units. At least one of the functional units is operable to perform data processing operations and at least a subset of the plurality of functional units have at least one of a respective co-processor register for storing configuration data and a respective debug register for storing debug data. A debug controller outputs debug data and co-ordinates debug operations. A configuration ring-bus provides a ring path for communication of configuration instructions between a first ring sequence of the plurality of functional units and a debug ring-bus provides a ring path for communication of the debug data between a second ring sequence of the plurality of functional units. Separate provision of the debug ring-bus and the configuration ring-bus provides independent access to the co-processor register and to the debug register.

    摘要翻译: 提供具有多个功能单元的数据处理装置。 功能单元中的至少一个可操作以执行数据处理操作,并且多个功能单元的至少一个子集具有用于存储配置数据的相应协处理器寄存器和用于存储调试数据的相应调试寄存器中的至少一个。 调试控制器输出调试数据并协调调试操作。 配置环总线提供用于在多个功能单元的第一环序列之间进行配置指令通信的环路径,并且调试环总线提供用于在多个功能单元的第二环序列之间的调试数据的通信的环路 功能单位。 调试环总线和配置环总线的单独提供可以独立访问协处理器寄存器和调试寄存器。

    Compare and branch mechanism
    10.
    发明申请
    Compare and branch mechanism 有权
    比较和分支机制

    公开(公告)号:US20050216712A1

    公开(公告)日:2005-09-29

    申请号:US10807499

    申请日:2004-03-24

    IPC分类号: G06F9/32 G06F9/42 G06F9/44

    CPC分类号: G06F9/30058 G06F9/4486

    摘要: A data processing system is provided that includes an instruction decoder 20 responsive to a compare and branch instruction CHKA.X that performs a comparison between first and second values stored in first and second registers Rn, Rm respectively. A target branch address is determined from a pre-programmed stored value and a branch to a sub-routine is performed in dependence upon a result of the comparison.

    摘要翻译: 提供了一种数据处理系统,其包括响应于分别执行存储在第一和第二寄存器Rn,Rm中的第一和第二值之间的比较的比较和转移指令CHKA.X的指令解码器20。 根据预编程的存储值确定目标分支地址,并且根据比较的结果执行到子程序的分支。