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    Injectable formulations of avermectins and milbemycins
    1.
    发明授权
    Injectable formulations of avermectins and milbemycins 有权
    阿维菌素和米尔倍霉素的注射制剂

    公开(公告)号：US06617314B2

    公开(公告)日：2003-09-09

    申请号：US09254615

    申请日：1999-03-10

    申请人： Michael Grosse-Bley ,  Richard Kujanek

    发明人： Michael Grosse-Bley ,  Richard Kujanek

    IPC分类号： A61K3170

    CPC分类号： A61K31/7048 ,  A61K9/0019 ,  A61K31/365 ,  A61K47/10 ,  A61K47/14 ,  A61K47/44 ,  Y10S514/943

    摘要： The present application relates to injection formulations of avermectins and milbemycins based on a solvent mixture comprising sesame oil, medium-chain triglycerides, glycol esters or fatty acid esters and a further solvent from the group consisting of mono- or polyhydric aliphatic or aromatic alcohols and their derivatives (e.g. cyclic carbonates; acetates; acetals; ketals) or castor oil.

    摘要翻译： 本申请涉及基于包含芝麻油，中链甘油三酯，乙二醇酯或脂肪酸酯的溶剂混合物的除虫菌素和米尔倍霉素的注射制剂，以及来自一元或多元脂肪族或芳族醇的其它溶剂及其 衍生物（例如环状碳酸酯;乙酸酯;缩醛;缩酮）或蓖麻油。

    Parasiticide formulations suitable for dermal application
    4.
    发明申请
    Parasiticide formulations suitable for dermal application 审中-公开
    适用于皮肤应用的寄生虫制剂

    公开(公告)号：US20060281792A1

    公开(公告)日：2006-12-14

    申请号：US11508055

    申请日：2006-08-21

    申请人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    发明人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    IPC分类号： A01N43/40

    CPC分类号： A01N51/00 ,  A01N61/00 ,  Y10S514/83 ,  A01N25/02 ,  A01N2300/00

    摘要： The present invention relates to formulations for the dermal control of parasitic insects on animals, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.

    摘要翻译： 本发明涉及用于对动物进行寄生昆虫的真皮控制的制剂，其具有下列成分：昆虫的烟碱能乙酰胆碱受体的激动剂或拮抗剂，其浓度为制剂总重量的1至20重量％; 基于制剂的总重量，来自组苯甲醇或任选取代的吡咯烷酮的溶剂的浓度为至少20重量％; 如果需要，基于制剂的总重量，浓度为5.0至80重量％的来自环状碳酸酯或内酯的另外的溶剂; 如果需要，基于制剂的总重量，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的其它助剂。

    Parasiticidal formulations that can be applied dermally
    5.
    发明授权
    Parasiticidal formulations that can be applied dermally 有权
    可以皮肤施用的寄生性制剂

    公开(公告)号：US06372765B1

    公开(公告)日：2002-04-16

    申请号：US09435271

    申请日：1999-11-05

    申请人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemüller ,  Terence Hopkins

    发明人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemüller ,  Terence Hopkins

    IPC分类号： H01N5100

    CPC分类号： A01N51/00 ,  A01N61/00 ,  Y10S514/83 ,  A01N25/02 ,  A01N2300/00

    摘要： The present invention relates to formulations for the dermal control of parasitic insects of animals, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.

    摘要翻译： 本发明涉及用于真皮对照动物寄生昆虫的制剂，其具有以下配合物或者拮抗剂，其浓度为制剂总重量的1至20重量％的昆虫的烟碱能乙酰胆碱受体;溶剂 基于组合物的总重量，基于苄基醇或任选取代的吡咯烷酮，其浓度为至少20重量％;如果需要，还可以使用浓度为5.0至最高的环状碳酸酯或内酯的另外的溶剂 基于制剂的总重量为80重量％;如果需要，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的更多助剂 基于制剂的总重量。

    Parasiticide formulations suitable for dermal application
    6.
    发明授权
    Parasiticide formulations suitable for dermal application 失效
    适用于皮肤应用的寄生虫制剂

    公开(公告)号：US6001858A

    公开(公告)日：1999-12-14

    申请号：US849259

    申请日：1997-06-02

    申请人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    发明人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    IPC分类号： A01N43/36 ,  A01N43/40 ,  A01N43/50 ,  A01N43/78 ,  A01N43/86 ,  A01N51/00 ,  A01N61/00

    CPC分类号： A01N51/00 ,  A01N61/00 ,  Y10S514/83

    摘要： The present invention relates to formulations for the dermal control of parasitic insects on animals, having the following compositionagonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation;solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation;if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation;if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.

    摘要翻译： PCT No.PCT / EP95 / 04667 Sec。 371日期：1997年6月2日 102（e）日期1997年6月2日PCT提交1995年11月27日PCT公布。 第WO96 / 17520号公报 日期1996年6月13日本发明涉及用于对动物进行寄生昆虫的真皮对照的制剂，其具有以下组成的组合物：浓度为1至20重量％的昆虫的烟碱能乙酰胆碱受体的激动剂或拮抗剂，基于总体 制剂重量; 基于制剂的总重量，来自组苯甲醇或任选取代的吡咯烷酮的溶剂的浓度为至少20重量％; 如果需要，基于制剂的总重量，浓度为5.0至80重量％的来自环状碳酸酯或内酯的另外的溶剂; 如果需要，基于制剂的总重量，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的其它助剂。