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公开(公告)号:US06331411B1
公开(公告)日:2001-12-18
申请号:US09153277
申请日:1998-09-15
申请人: Michael Gwynn , Howard Kallender , Lisa K Katz , Daniel Sylvester , Christopher M Traini , Richard Lloyd Warren
发明人: Michael Gwynn , Howard Kallender , Lisa K Katz , Daniel Sylvester , Christopher M Traini , Richard Lloyd Warren
IPC分类号: C12N510
CPC分类号: C12N9/90 , A61K38/00 , C07K14/3156 , C12Q1/689
摘要: The invention provides topA polypeptides and polynucleotides encoding topA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing topA polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了topA多肽和编码topA多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用topA多肽筛选抗菌化合物的方法。