-
公开(公告)号：US20120245538A1
公开(公告)日：2012-09-27
申请号：US13512403
申请日：2010-12-02
摘要： The invention relates to a transdermal therapeutic system (TTS) which is suited for the administration of a peptide to a patient through skin treated with ablation. The transdermal therapeutic system incorporates a back layer and an active substance-containing layer that includes at least one peptide and a carrier substance.
摘要翻译： 本发明涉及一种透皮治疗系统（TTS），其适于通过用消融治疗的皮肤向患者施用肽。 透皮治疗系统包含背层和含有至少一种肽和载体物质的含活性物质的层。
-
公开(公告)号：US10772845B2
公开(公告)日：2020-09-15
申请号：US13512403
申请日：2010-12-02
IPC分类号： A61K38/09 , A61K9/70 , A61K38/095
摘要： The invention relates to a transdermal therapeutic system (TTS) which is suited for the administration of a peptide to a patient through skin treated with ablation. The transdermal therapeutic system incorporates a back layer and an active substance-containing layer that includes at least one peptide and a carrier substance.
-
公开(公告)号：US09895319B2
公开(公告)日：2018-02-20
申请号：US13512520
申请日：2010-12-02
CPC分类号： A61K9/7084 , A61K38/24 , A61K38/27
摘要： The invention relates to a transdermal therapeutic system (TTS), which is suited for the administration of a peptide to a patient through skin treated with ablation. The transdermal therapeutic system includes a back layer and an active substance-containing layer that contains at least one peptide and a carrier substance, preferably as a textile web material.
-
公开(公告)号：US20100310634A1
公开(公告)日：2010-12-09
申请号：US12865465
申请日：2008-12-09
CPC分类号： A61K9/7061
摘要： The invention relates to a transdermal therapeutic system (TTS) for administering pharmaceutical agents through the skin, comprising a back layer (R) impermeable to the agent and at least one layer (S) comprising the agent, wherein the layer (H) facing the skin comprises urea in solid form, allowing continuous administration of large quantities of agent over a long period of time.
摘要翻译： 本发明涉及一种用于通过皮肤施用药剂的透皮治疗系统（TTS），其包括不可渗透到所述药剂的背层（R）和包含所述药剂的至少一层（S），其中所述层（H） 皮肤包含固体形式的尿素，允许长时间连续施用大量的药剂。
-
公开(公告)号：US09066887B2
公开(公告)日：2015-06-30
申请号：US12865465
申请日：2008-12-09
CPC分类号： A61K9/7061
摘要： The invention relates to a transdermal therapeutic system (TTS) for administering pharmaceutical agents through the skin, comprising a back layer (R) impermeable to the agent and at least one layer (S) comprising the agent, wherein the layer (H) facing the skin comprises urea in solid form, allowing continuous administration of large quantities of agent over a long period of time.
摘要翻译： 本发明涉及一种用于通过皮肤施用药剂的透皮治疗系统（TTS），其包括不可渗透到所述药剂的背层（R）和包含所述药剂的至少一层（S），其中所述层（H） 皮肤包含固体形式的尿素，允许长时间连续施用大量的药剂。
-
公开(公告)号：US20120238942A1
公开(公告)日：2012-09-20
申请号：US13512520
申请日：2010-12-02
CPC分类号： A61K9/7084 , A61K38/24 , A61K38/27
摘要： The invention relates to a transdermal therapeutic system (TTS), which is suited for the administration of a peptide to a patient through skin treated with ablation. The transdermal therapeutic system includes a back layer and an active substance-containing layer that contains at least one peptide and a carrier substance, preferably as a textile web material.
摘要翻译： 本发明涉及一种透皮治疗系统（TTS），其适于通过用消融治疗的皮肤向患者施用肽。 透皮治疗系统包括背层和含有至少一种肽和载体物质的活性物质含有层，优选作为织物网材料。
-
7.发明授权Method and device for inserting a plurality of individual sheetlike forms of administration in a dispenser by forming a multilayer pile 有权通过形成多层桩将多个单独的片状给药形式插入分配器中的方法和装置公开(公告)号：US06659442B1
公开(公告)日：2003-12-09
申请号：US09622562
申请日：2000-09-20
IPC分类号： B65H3916
CPC分类号： B65H35/06 , A61K9/006 , B65H39/16 , B65H2701/1752 , B65H2701/176 , Y10T83/2042 , Y10T83/2046 , Y10T83/222
摘要： A process for introducing a plurality of segregated sheet-like administration forms into a dispenser under formation of a multilayered stack for individually dosable removal, with sheet-like tapes wound-up on rolls being present as starting material, utilizes the following steps. In a first step, a number of sheet-like layers of said tapes, which number corresponds to the stack, is simultaneously drawn from a plurality of rolls. In a further step, the individual tapes are united, using guide means, to form a multilayered strand, which in yet another step, is drawn forward to a cutting station where one length of stack is severed at a time, and wherein a length segment of the multilayered strand corresponding to the stack is substantially in the dispenser prior to being severed from a remainder of the multilayered strand by the cutting device.
摘要翻译： 一种将多个分离的片状给药形式引入到分配器中的方法，该分配器形成多层堆叠以进行单独的剂量去除，卷材卷绕在辊上作为起始材料，利用以下步骤。 在第一步骤中，从多个辊同时拉出数个对应于堆叠的所述带的多个片状层。 在另一步骤中，使用引导装置将各个带组合在一起形成多层股线，该多股股票在另一个步骤中被向前拉到切割站，其中一次堆叠被一次切断，并且其中长度段 对应于堆叠的多层股线在通过切割装置从剩余的多层股线切断之前基本上在分配器中。
-
8.发明授权Transdermal therapeutic system comprising the active subtance 17-.beta.-Estradiol (Anhydrous) 失效透皮治疗系统包含活性物质17-β-雌二醇（无水）
公开(公告)号：US5827245A
公开(公告)日：1998-10-27
申请号：US854205
申请日：1997-05-09
申请人： Michael Horstmann , Marion Kursawe , Horst Dzekan
发明人： Michael Horstmann , Marion Kursawe , Horst Dzekan
IPC分类号： A61K9/70 , A61K31/565 , A61F13/02 , A61K9/16
CPC分类号： A61K9/7053 , A61K31/565 , A61K9/7061 , A61K9/7092
摘要： A transdermal therapeutic system containing the active substance 17-.beta.-estradiol and optionally further active substances has a laminated structure positioned on a backing layer which is essentially impermeable to active substance and moisture, at least one matrix layer and optionally an adhesive layer. The at least one matrix layer or the adhesive layer contains anhydrous 17-.beta.-estradiol in crystalline form.
摘要翻译： 含有活性物质17-β-雌二醇和任选的其它活性物质的透皮治疗系统具有位于背衬层上的层压结构，其基本上不渗透活性物质和水分，至少一种基质层和任选的粘合剂层。 至少一个基质层或粘合剂层含有结晶形式的无水17-β-雌二醇。
-
9.发明申请Transdermal Therapeutic System for Volatile and/or Thermo-Labile Substances 审中-公开用于挥发性和/或热不稳定物质的透皮治疗系统公开(公告)号：US20100166836A1
公开(公告)日：2010-07-01
申请号：US12160641
申请日：2006-12-16
申请人： Tobias Jung , Michael Horstmann , Horst Dzekan
发明人： Tobias Jung , Michael Horstmann , Horst Dzekan
IPC分类号： A61K31/4439 , A61K9/70 , A61P25/34 , A61F13/02
CPC分类号： A61K9/703 , A61F2013/0296 , A61K9/7084
摘要： The present invention relates to a transdermal therapeutic system comprising at least one readily volatile and/or thermolabile active ingredient and/or auxiliary, which can be produced by laminating at least three components onto one another, namely a polymeric matrix layer, a likewise polymeric acceptor layer that absorbs the active ingredient and/or auxiliary at an increased rate, and a donor layer comprising, at the point of production, the volatile and/or thermolabile active ingredient and/or auxiliary. The system according to the invention is characterized in that, during or shortly after the lamination process, the donor layer combines with the acceptor layer as a result of migration of the readily volatile and/or thermolabile substances.
摘要翻译： 本发明涉及一种透皮治疗系统，其包括至少一种容易挥发和/或不耐热的活性成分和/或辅助剂，其可以通过将至少三种组分彼此层压而制备，即聚合物基质层，同样的聚合受体 层，其以增加的速率吸收活性成分和/或辅助剂;以及供体层，其在生产时包含挥发性和/或不耐热活性成分和/或辅助剂。 根据本发明的系统的特征在于，在层压过程中或不久之后，由于容易挥发和/或不耐热物质的迁移，施主层与受体层结合。
-
10.发明授权Method and device for inserting a plurality of individual sheetlike forms of administration in a dispenser by forming a multilayer pile 有权通过形成多层桩将多个单独的片状给药形式插入分配器中的方法和装置公开(公告)号：US07175172B2
公开(公告)日：2007-02-13
申请号：US10658027
申请日：2003-09-09
IPC分类号： B65H39/16
CPC分类号： B65H35/06 , A61K9/006 , B65H39/16 , B65H2701/1752 , B65H2701/176 , Y10T83/2042 , Y10T83/2046 , Y10T83/222
摘要： A process for introducing a plurality of segregated sheet-like administration forms into a dispenser under formation of a multilayered stack for individually dosable removal, with sheet-like tapes wound-up on rolls being present as starting material, utilizes the following steps. In a first step, a number of sheet-like layers of said tapes, which number corresponds to the stack, is simultaneously drawn from a plurality of rolls. In a further step, the individual tapes are united, using guide means, to form a multilayered strand, which in yet another step, is drawn forward to a cutting station where one length of stack is severed at a time, and wherein a length segment of the multilayered strand corresponding to the stack is substantially in the dispenser prior to being severed from a remainder of the multilayered strand by the cutting device.
摘要翻译： 一种将多个分离的片状给药形式引入到分配器中的方法，该分配器形成多层堆叠以进行单独的剂量去除，卷材卷绕在辊上作为起始材料，利用以下步骤。 在第一步骤中，从多个辊同时拉出数个对应于堆叠的所述带的多个片状层。 在另一步骤中，使用引导装置将各个带组合在一起形成多层股线，该多股股票在另一个步骤中被向前拉到切割站，其中一次堆叠被一次切断，并且其中长度段 对应于堆叠的多层股线在通过切割装置从剩余的多层股线切断之前基本上在分配器中。
-
-
-
-
-
-
-
-
-
搜索结果
71 条记录 (耗时 0.018 秒)