公开(公告)号：US20070156186A1

公开(公告)日：2007-07-05

申请号：US11685611

申请日：2007-03-13

申请人： Michael Lee ,  Daniel Vinup ,  Steven Goetz

发明人： Michael Lee ,  Daniel Vinup ,  Steven Goetz

IPC分类号： A61N1/36

CPC分类号： A61N1/37247 ,  A61N1/36071 ,  A61N1/36132 ,  G06F19/00 ,  G06F19/3481 ,  G16H10/60 ,  G16H40/40

摘要： An implantable medical device delivers neurostimulation therapy to a patient according to a parameter set. A parameter set may consist of a number of programs that are delivered substantially simultaneously. When programming the implantable medical device for the patient, a clinician programmer may maintain a session log for the patient that includes a listing of programs delivered to the patient and rating information provided by a clinician and the patient for programs of the list. The listing may be ordered according to the rating information in order to facilitate the selection of programs for a parameter set. A program library that may include particularly effective programs organized according to a directory structure may be stored in a memory. One or both of the implantable medical device and a patient programmer may store usage information that provides an objective assessment of therapy use by the patient, and allows a clinician to later improve the therapy based on the usage information.

摘要翻译： 植入式医疗装置根据参数组向患者传递神经刺激疗法。 参数集可以包括大量同时传送的多个节目。 当编程用于患者的可植入医疗装置时，临床医生程序员可以维护患者的会话日志，其包括递送给患者的程序的列表以及由临床医生和患者提供的用于该列表的程序的评估信息。 可以根据评级信息对列表进行排序，以便于选择参数集的程序。 可以包括根据目录结构组织的特别有效的程序的程序库可以存储在存储器中。 可植入医疗装置和患者编程器中的一个或两个可以存储提供患者的治疗使用的客观评估的使用信息，并且允许临床医生随后基于使用信息来改进治疗。

公开(公告)号：US20060229687A1

公开(公告)日：2006-10-12

申请号：US11352389

申请日：2006-02-10

申请人： Steven Goetz ,  Andrew Houchins ,  Jeffrey Keacher ,  Gary King ,  Kenneth Heruth ,  Roy Testerman ,  Michael Lee ,  Nathan Torgerson ,  Joseph Nolan

发明人： Steven Goetz ,  Andrew Houchins ,  Jeffrey Keacher ,  Gary King ,  Kenneth Heruth ,  Roy Testerman ,  Michael Lee ,  Nathan Torgerson ,  Joseph Nolan

IPC分类号： A61N1/18

CPC分类号： A61N1/36185 ,  A61N1/36071

摘要： In general, the invention is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. The stimulation pulses of the first and second electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, thereby allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find the most efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.

摘要翻译： 通常，本发明涉及用于在两个电极组合之间移动的技术。 第一电极组合的振幅逐渐减小，而第二或随后的电极组合的振幅同时递增地增加。 第一和第二电极组合的刺激脉冲在时间上交付给患者。 以这种方式，本发明提供了从第一电极组合到第二电极组合的平滑的逐渐变化，从而允许患者保持对刺激的连续感知。 在编程期间可以使用本文描述的移位技术来在不同的电极组合之间移动以找到最有效的电极组合。 另外，这些技术可用于在与不同刺激程序或程序集相关联的不同电极组合之间进行移位。

公开(公告)号：US20060259099A1

公开(公告)日：2006-11-16

申请号：US11401100

申请日：2006-04-10

申请人： Steven Goetz ,  Andrew Houchins ,  Jeffrey Keacher ,  Gary King ,  Kenneth Heruth ,  Roy Testerman ,  Michael Lee ,  Nathan Torgerson ,  Joseph Nolan

发明人： Steven Goetz ,  Andrew Houchins ,  Jeffrey Keacher ,  Gary King ,  Kenneth Heruth ,  Roy Testerman ,  Michael Lee ,  Nathan Torgerson ,  Joseph Nolan

IPC分类号： A61N1/36

CPC分类号： A61N1/37247 ,  A61N1/36071 ,  A61N1/36185 ,  A61N1/37252

摘要： The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.

公开(公告)号：US20070123953A1

公开(公告)日：2007-05-31

申请号：US11698655

申请日：2007-01-26

申请人： Michael Lee ,  Steven Goetz ,  Nathan Torgerson

发明人： Michael Lee ,  Steven Goetz ,  Nathan Torgerson

IPC分类号： A61N1/32

CPC分类号： A61N1/37247 ,  A61N1/36082 ,  A61N1/36185 ,  Y10S128/903

摘要： A programmer allows a clinician to identify desirable combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The clinician may create neurostimulation therapy programs that include identified desirable electrode combinations. In some embodiments, the clinician may use the programmer to select a program, such as a program identified during a neurostimulation programming session, and direct the programmer to replicate the selected program. The programmer may change one or more parameters of the selected program, such as pulse amplitude or duty cycle, when generating the copy of the selected program. In some embodiments, the programmer may associate each of a plurality of programs identified during a neurostimulation therapy programming session with one or more program categories, and may automatically generate program groups that include two or more of the programs based on the program categories.

摘要翻译： 程序员允许临床医生从植入患者体内的电极组中识别电极的期望组合，从而能够通过可植入医疗装置递送所需的神经刺激疗法。 临床医生可以产生神经刺激治疗程序，其包括所识别的期望的电极组合。 在一些实施例中，临床医生可以使用编程器来选择程序，诸如在神经刺激编程会话期间识别的程序，并指示程序员复制所选择的程序。 当生成所选程序的副本时，编程器可以改变所选程序的一个或多个参数，例如脉冲幅度或占空比。 在一些实施例中，程序员可以将在神经刺激治疗程序设计会话期间识别的多个程序中的每一个与一个或多个程序类别相关联，并且可以基于程序类别自动生成包括两个或更多程序的程序组。

公开(公告)号：US20060235472A1

公开(公告)日：2006-10-19

申请号：US11388227

申请日：2006-03-23

申请人： Steven Goetz ,  Michael Lee

发明人： Steven Goetz ,  Michael Lee

IPC分类号： A61K9/22 ,  A61N1/00

CPC分类号： A61N1/36135 ,  A61N1/37247 ,  A61N1/37264 ,  G06F19/00

摘要： A programming device used to program delivery of therapy to a patient by a medical device, such as an implantable neurostimulator or pump, maintains or accesses a programming history for the patient. The programming history may take the form of a record of programs, e.g., combinations of therapy parameters, tested during one or more prior programming sessions. The programming device may analyze, or otherwise use the programming history to provide guidance information to a user, such as a clinician, which may assist the user in more quickly identifying one or more desirable programs during a current programming session.

摘要翻译： 用于通过诸如可植入神经刺激器或泵的医疗装置向患者传递治疗的程序设备维护或访问患者的编程历史。 编程历史可以采取程序记录的形式，例如在一个或多个在先的编程会话期间测试的治疗参数的组合。 编程设备可以分析或以其他方式使用编程历史来向诸如临床医师的用户提供指导信息，其可以在当前的编程会话期间帮助用户更快速地识别一个或多个期望的程序。

公开(公告)号：US20060020292A1

公开(公告)日：2006-01-26

申请号：US11186383

申请日：2005-07-20

申请人： Steven Goetz ,  Michael Lee

发明人： Steven Goetz ,  Michael Lee

IPC分类号： A61N1/00 ,  A61K9/22

CPC分类号： A61N1/37252 ,  A61N1/36007 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/37247

摘要： A programming device used to program delivery of therapy to a patient by a medical device, such as an implantable neurostimulator or pump, maintains or accesses a programming history for the patient. The programming history may take the form of a record of programs, e.g., combinations of therapy parameters, tested during one or more prior programming sessions. The programming device may analyze, or otherwise use the programming history to provide guidance information to a user, such as a clinician, which may assist the user in more quickly identifying one or more desirable programs during a current programming session.

公开(公告)号：US20060265025A1

公开(公告)日：2006-11-23

申请号：US11414786

申请日：2006-04-28

申请人： Steven Goetz ,  Nathan Torgerson ,  Michael Lee

发明人： Steven Goetz ,  Nathan Torgerson ,  Michael Lee

IPC分类号： A61N1/00

CPC分类号： A61N1/37 ,  A61N1/36114 ,  A61N1/3706 ,  A61N2001/083

摘要： Techniques for performing lead functionality tests, e.g., lead impedance tests, for implantable electrical leads are described. In some of the described embodiments, an implantable medical device determines whether a patient is in a target activity state, e.g., an activity state in which lead impedance testing will be unobtrusive, such as when a patient is asleep, or capture information of particular interest, such as when the patient is active, in a particular posture, or changing postures. The implantable medical device performs the lead functionality test based on this determination. Additionally, in some embodiments, the implantable medical device may group a plurality of measurements for a single lead functionality test into a plurality of sessions, and perform the measurement sessions interleaved with delivery of therapeutic stimulation.

摘要翻译： 描述了用于执行用于可植入电引线的引线功能测试（例如引线阻抗测试）的技术。 在一些所描述的实施例中，可植入医疗设备确定患者是否处于目标活动状态，例如，其中导线阻抗测试将是不显眼的活动状态，例如当患者睡着时或捕获特定感兴趣的信息 ，例如当患者活跃时，处于特定姿势，或改变姿势。 可植入医疗装置基于该确定执行引导功能测试。 另外，在一些实施例中，可植入医疗装置可以将用于单个引线功能测试的多个测量分组成多个会话，并且执行与递送治疗性刺激交错的测量会话。

公开(公告)号：US20060265024A1

公开(公告)日：2006-11-23

申请号：US11414536

申请日：2006-04-28

申请人： Steven Goetz ,  Nathan Torgerson ,  Michael Lee

发明人： Steven Goetz ,  Nathan Torgerson ,  Michael Lee

IPC分类号： A61N1/00

CPC分类号： A61N1/37 ,  A61N1/36114 ,  A61N1/3706 ,  A61N2001/083

摘要： Techniques for performing lead functionality tests, e.g., lead impedance tests, for implantable electrical leads are described. In some of the described embodiments, an implantable medical device determines whether a patient is in a target activity state, e.g., an activity state in which lead impedance testing will be unobtrusive, such as when a patient is asleep, or capture information of particular interest, such as when the patient is active, in a particular posture, or changing postures. The implantable medical device performs the lead functionality test based on this determination. Additionally, in some embodiments, the implantable medical device may group a plurality of measurements for a single lead functionality test into a plurality of sessions, and perform the measurement sessions interleaved with delivery of therapeutic stimulation.

公开(公告)号：US20060195145A1

公开(公告)日：2006-08-31

申请号：US11404069

申请日：2006-04-13

申请人： Michael Lee ,  Steven Goetz ,  Nathan Torgerson

发明人： Michael Lee ,  Steven Goetz ,  Nathan Torgerson

IPC分类号： A61N1/05 ,  A61N1/00

CPC分类号： A61N1/37247 ,  A61N1/36082 ,  A61N1/36185 ,  Y10S128/903

摘要： A programmer allows a clinician to identify combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The programmer executes an electrode combination search algorithm to select combinations of electrodes to test in a non-random order. According to algorithms consistent with the invention, the programmer may first identify a position of a first cathode for subsequent combinations, and then select electrodes from the set to test with the first cathode as anodes or additional cathodes based on the proximity of the electrodes to the first cathode. The programmer may store information for each combination tested, and the information may facilitate the identification of desirable electrode combinations by the clinician. The clinician may create neurostimulation therapy programs that include identified desirable program combinations.

公开(公告)号：US09149210B2

公开(公告)日：2015-10-06

申请号：US12769391

申请日：2010-04-28

申请人： Rajeev M. Sahasrabudhe ,  Lynn Davenport ,  Jon P. Davis ,  Wende L. Dewing ,  Elizabeth A. Fehrmann ,  Steven Goetz ,  Shyam Gokaldas ,  Eric J. Panken

发明人： Rajeev M. Sahasrabudhe ,  Lynn Davenport ,  Jon P. Davis ,  Wende L. Dewing ,  Elizabeth A. Fehrmann ,  Steven Goetz ,  Shyam Gokaldas ,  Eric J. Panken

IPC分类号： A61B5/11 ,  A61B5/00 ,  A61N1/36 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/145 ,  A61N1/365 ,  A61N1/372 ,  G06F19/00

CPC分类号： A61B5/4839 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/686 ,  A61B5/7264 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/7475 ,  A61B2560/0223 ,  A61B2560/0475 ,  A61N1/36071 ,  A61N1/36535 ,  A61N1/37247 ,  G06F19/00 ,  G06F19/324 ,  G16H50/20

摘要： Techniques relate to operating a medical device by classifying a detected posture state of a patient. This classification may be performed by comparing the detected posture state to posture state definitions available within the system. Each definition may be described in terms of a parameter (e.g., vector) indicative of a direction in three-dimensional space. The posture state definitions may be calibrated by automatically estimating values for these parameters, thereby eliminating the need for the patient to assume each posture state during the calibration process to capture actual parameter values. According to another aspect, the estimated parameter values may be updated as the patient assumes various postures during a daily routine. For instance, estimated vectors initially used to calibrate the posture state definitions may be changed over time to more closely represent posture states the patient actually assumes, and to further adapt to changes in a patient's condition.

摘要翻译： 技术涉及通过对检测到的患者的姿势状态进行分类来操作医疗装置。 可以通过将检测到的姿势状态与系统内可用的姿势状态定义进行比较来执行该分类。 可以根据指示三维空间中的方向的参数（例如，矢量）来描述每个定义。 可以通过自动估计这些参数的值来校准姿势状态定义，从而消除了在校准过程期间患者承担每个姿势状态以捕获实际参数值的需要。 根据另一方面，当患者在日常例行程序中呈现各种姿势时，可以更新所估计的参数值。 例如，最初用于校准姿势状态定义的估计矢量可以随着时间而改变以更加紧密地表示患者实际假定的姿势状态，并进一步适应患者状况的变化。