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15 条记录 (耗时 0.039 秒)

    Surface-enhanced spectroscopy-active sandwich nanoparticles
    6.
    发明申请
    Surface-enhanced spectroscopy-active sandwich nanoparticles 有权

    公开(公告)号：US20050208665A1

    公开(公告)日：2005-09-22

    申请号：US11133926

    申请日：2005-05-20

    申请人： Michael Natan

    发明人： Michael Natan

    IPC分类号： G01J3/44 ,  G01N21/65 ,  G01N31/00 ,  G01N37/00

    CPC分类号： G01N21/658 ,  G01J3/44 ,  Y10T436/10 ,  Y10T436/13

    摘要： Surface-enhanced Raman spectroscopy (SERS) uses nanoscale metal particles (SERS-active particles) or surface roughness to enhance the Raman signal of Raman-active analytes contacting the surface. SERS sandwich particles contain SERS-active particles sandwiching a Raman-active substance and serve as optical tags. Preferably, the particles are rod-shaped, with each layer (SERS-active and Raman-active) formed as a distinct stripe of the particle. These freestanding particles can be derivatized with surface ligands capable of associating with analytes of interest in, for example, a biological sample. The acquired Raman spectrum of the particle encodes the identity of the ligand. Because of the simplicity and intensity of Raman spectra, highly multiplexed assays are capable using SERS particles with different Raman-active species.

    CATALYTIC NANOTEMPLATES
    7.
    发明申请
    CATALYTIC NANOTEMPLATES 有权
    催化纳米微粒

    公开(公告)号：US20080096019A1

    公开(公告)日：2008-04-24

    申请号：US11753433

    申请日：2007-05-24

    申请人： Michael Natan

    发明人： Michael Natan

    IPC分类号： B32B9/00 ,  B28B1/14

    CPC分类号： B82Y30/00 ,  Y10S977/89 ,  Y10T428/2991

    摘要： A catalytic nanotemplate including a freestanding template particle and a director associated with the surface of the freestanding template particle. The free standing template particle may have multiple segments and the director may be associated with one or more of the segments. In instances where multiple segments are present, the segments may be made of different materials or be of the same material in different forms. More than one type of director or no director may be associated with any particular segment.

    摘要翻译： 催化纳米模板，包括独立模板颗粒和与独立模板颗粒的表面相关联的导向体。 自由站立模板粒子可以具有多个片段，并且该引导器可以与一个或多个片段相关联。 在存在多个片段的情况下，片段可以由不同的材料制成，或由不同形式的相同材料制成。 不止一种类型的董事或任何董事可能与任何特定细分相关联。

    Nanoparticulate Chemical Sensors Using SERS
    8.
    发明申请
    Nanoparticulate Chemical Sensors Using SERS 有权
    使用SERS的纳米微粒化学传感器

    公开(公告)号：US20070259437A1

    公开(公告)日：2007-11-08

    申请号：US11611052

    申请日：2006-12-14

    申请人： Michael Natan ,  Marcelo Piotti

    发明人： Michael Natan ,  Marcelo Piotti

    IPC分类号： G01N33/20

    CPC分类号： G01N21/658

    摘要： A system to selectively deliver relatively small analyte molecules of interest to a SERS-active nanoparticle surface while excluding dozens to hundreds of other species in the environment. In particular, the present invention provides a permselective film that renders the particles of interest as viable small molecule optically addressable sensors.

    摘要翻译： 选择性地向SERS-活性纳米颗粒表面递送所需感兴趣的相对较小的分析物分子的系统，同时在环境中排除数十至数百种其它物质。 特别地，本发明提供了一种选择性薄膜，其使感兴趣的颗粒成为可行的小分子光可寻址传感器。