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    SOL-GEL KIT FOR PREPARING BIOCHIP AND METHODS FOR PREPARING BIOCHIP USING THE SAME
    3.
    发明申请
    SOL-GEL KIT FOR PREPARING BIOCHIP AND METHODS FOR PREPARING BIOCHIP USING THE SAME 审中-公开
    用于制备生物化学品的溶胶凝胶试剂盒及其制备方法

    公开(公告)号：US20160038903A1

    公开(公告)日：2016-02-11

    申请号：US14822540

    申请日：2015-08-10

    申请人： PCL, INC.

    发明人： Minjoung Jo ,  Seram Lee

    IPC分类号： B01J19/00

    CPC分类号： B01J19/0046 ,  B01J2219/00315 ,  B01J2219/0036 ,  B01J2219/00364 ,  B01J2219/00385 ,  B01J2219/00599 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00657 ,  B01J2219/00725

    摘要： A method of preparing a protein chip by gelation of a sol composition. In the method, a mixture of specific silicate monomers, such as SolB1, SolB2 and SolB3, SolBH, and a mixture of SolBS, distilled water and a detector protein are mixed sequentially, so that the gelation rate of the sol-composition can be delayed, thus inducing the stable gelation of the composition. Also, the biochip can be fabricated in a simple and easy manner by dispensing the sol composition by hand using an arrayer or a tool such as a pipette. In addition, a uniform biochip can be prepared by dispensing the sol composition, solution I (SolBH) and solution II (a mixture of buffer, SolBS, distilled water and a detector protein) sequentially onto a substrate without needing a conventional pretreatment process such as mixing.

    摘要翻译： 一种通过凝胶化溶胶组合物制备蛋白质芯片的方法。 在该方法中，依次混合特定硅酸盐单体如SolB1，SolB2和SolB3，SolBH和SolBS，蒸馏水和检测器蛋白的混合物的混合物，使得溶胶组合物的凝胶化速率可以延迟 ，从而诱导组合物的稳定凝胶化。 此外，生物芯片可以通过使用排液器或诸如移液管的工具通过手动分配溶胶组合物以简单和容易的方式制造。 此外，可以通过将溶胶组合物溶液I（SolBH）和溶液II（缓冲液，SolBS，蒸馏水和检测器蛋白质的混合物）顺序分配到基底上而不需要常规的预处理过程例如 混合。

    Sol-gel kit for preparing biochip and method for preparing biochip using the same
    5.
    发明授权
    Sol-gel kit for preparing biochip and method for preparing biochip using the same 有权
    用于制备生物芯片的溶胶凝胶试剂盒及其制备方法

    公开(公告)号：US09101902B2

    公开(公告)日：2015-08-11

    申请号：US13096991

    申请日：2011-04-28

    申请人： Minjoung Jo ,  Seram Lee

    发明人： Minjoung Jo ,  Seram Lee

    IPC分类号： B01J19/00

    CPC分类号： B01J19/0046 ,  B01J2219/00315 ,  B01J2219/0036 ,  B01J2219/00364 ,  B01J2219/00385 ,  B01J2219/00599 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00657 ,  B01J2219/00725

    摘要： A method of preparing a protein chip by gelation of a sol composition. In the method, a mixture of specific silicate monomers, such as SolB1, SolB2 and SolB3, SolBH, and a mixture of SolBS, distilled water and a detector protein are mixed sequentially, so that the gelation rate of the sol composition can be delayed, thus inducing the stable gelation of the composition. Also, the biochip can be fabricated in a simple and easy manner by dispensing the sol composition by hand using an arrayer or a tool such as a pipette. In addition, a uniform biochip can be prepared by dispensing the sol composition, solution I (SolBH) and solution II (a mixture of buffer, SolBS, distilled water and a detector protein) sequentially onto a substrate without needing a conventional pretreatment process such as mixing.

    摘要翻译： 一种通过凝胶化溶胶组合物制备蛋白质芯片的方法。 在该方法中，依次混合特定硅酸盐单体如SolB1，SolB2和SolB3，SolBH和SolBS，蒸馏水和检测器蛋白的混合物的混合物，使得溶胶组合物的凝胶化速率可以延迟， 从而导致组合物的稳定凝胶化。 此外，生物芯片可以通过使用排液器或诸如移液管的工具通过手动分配溶胶组合物以简单和容易的方式制造。 此外，可以通过将溶胶组合物溶液I（SolBH）和溶液II（缓冲液，SolBS，蒸馏水和检测器蛋白质的混合物）顺序分配到基底上而不需要常规的预处理过程例如 混合。

    Apparatus for storing and dispensing reagent beads
    7.
    发明授权
    Apparatus for storing and dispensing reagent beads 有权
    用于存储和分配试剂珠的装置

    公开(公告)号：US08747782B2

    公开(公告)日：2014-06-10

    申请号：US13849640

    申请日：2013-03-25

    申请人： Cepheid

    发明人： Ronald Chang ,  Douglas B. Dority ,  Steven Montgomery

    IPC分类号： B01L9/00 ,  B23Q7/04 ,  G07F11/16 ,  B65H5/00 ,  B65H1/08 ,  B65H3/00

    CPC分类号： B01L3/527 ,  B01J19/0046 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00657 ,  B01L3/0289 ,  B01L2200/0647 ,  B01L2200/16 ,  G01N2035/00574 ,  Y10T436/25

    摘要： Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In one embodiment, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.

    摘要翻译： 本发明的实施方案提供了用于存储和分配试剂珠的有效和有效的技术。 在一个实施例中，提供了一种用于分配包含在珠子存储装置中的试剂珠粒的装置，其包括具有多个孔的珠粒载体; 设置在所述孔中的多个试剂珠; 以及可剥离地附接到胎圈载体以覆盖孔并将试剂珠保持在孔中的覆盖带。 该装置包括一个通道，在该通道中，珠子存放装置使胎圈承载件面向通道的支撑壁，盖带面向通道的剥离壁。 剥离壁包括设置在剥离边缘和相对边缘之间的剥离间隙，以及在剥离壁的与剥离边缘相对的一侧上邻近相对边缘设置的分配开口。 覆盖带可以通过剥离间隙被插入以被拉靠在剥离边缘上，以从胎圈载体上剥离覆盖带，以将通道内的胎圈载体的孔移动到分配开口，并单独暴露孔以分配试剂珠 。