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    Methods & Compositions For Enhancing Pharmaceutical Treatments
    1.
    发明申请
    Methods & Compositions For Enhancing Pharmaceutical Treatments 审中-公开
    用于增强药物治疗的方法和组合

    公开(公告)号：US20070203215A1

    公开(公告)日：2007-08-30

    申请号：US11627289

    申请日：2007-01-25

    申请人： Michael Newman ,  William Dixon

    发明人： Michael Newman ,  William Dixon

    IPC分类号： A61K31/417

    CPC分类号： C07D233/64 ,  A61K31/415 ,  A61K31/417 ,  A61K45/06 ,  A61K2300/00

    摘要： Improved methods are provided for therapeutic and/or preventative treatment to a mammal in which the mammal is protected against the toxicity of active pharmaceutical agents that (i) bind to or are substrates for P-gp, (ii) are taxane analogues, and/or (iii) are inhibitors of tubulin disassembly. Additionally provided are compositions and methods useful for treating cell proliferative disorders. Further provided are methods of increasing the bioavailability of therapeutic and/or preventative treatments in a mammal. Particular embodiments are directed to increasing such bioavailability across the blood-brain barrier.

    摘要翻译： 提供了用于治疗和/或预防性治疗哺乳动物的改进方法，其中所述哺乳动物被保护免受活性药剂的毒性，所述活性药剂（i）与P-gp结合或是底物，（ii）是紫杉烷类似物和/ 或（iii）是微管蛋白分解的抑制剂。 另外提供了可用于治疗细胞增殖性疾病的组合物和方法。 还提供了增加哺乳动物中治疗和/或预防性治疗的生物利用度的方法。 具体实施方案涉及通过血脑屏障增加这种生物利用度。

    Configurable speech recognition system using multiple recognizers
    2.
    发明授权
    Configurable speech recognition system using multiple recognizers 有权
    可配置的语音识别系统使用多个识别器

    公开(公告)号：US08898065B2

    公开(公告)日：2014-11-25

    申请号：US13345265

    申请日：2012-01-06

    申请人： Michael Newman ,  Anthony Gillet ,  David Mark Krowitz ,  Michael D. Edgington

    发明人： Michael Newman ,  Anthony Gillet ,  David Mark Krowitz ,  Michael D. Edgington

    IPC分类号： G10L15/00

    CPC分类号： G10L15/30 ,  G10L15/22 ,  G10L15/32 ,  G10L17/005

    摘要： Techniques for combining the results of multiple recognizers in a distributed speech recognition architecture. Speech data input to a client device is encoded and processed both locally and remotely by different recognizers configured to be proficient at different speech recognition tasks. The client/server architecture is configurable to enable network providers to specify a policy directed to a trade-off between reducing recognition latency perceived by a user and usage of network resources. The results of the local and remote speech recognition engines are combined based, at least in part, on logic stored by one or more components of the client/server architecture.

    摘要翻译： 在分布式语音识别架构中组合多个识别器的结果的技术。 输入到客户端设备的语音数据由本地和远程地由不同的识别器进行编码和处理，该识别器被配置为精通不同语音识别任务。 客户端/服务器体系结构是可配置的，以使网络提供商能够指定针对在减少用户感知的识别延迟和使用网络资源之间进行权衡的策略。 本地和远程语音识别引擎的结果至少部分地基于由客户端/服务器架构的一个或多个组件存储的逻辑。

    Cross-flow spiral heat transfer system
    3.
    发明授权
    Cross-flow spiral heat transfer system 有权
    交叉螺旋传热系统

    公开(公告)号：US08333087B2

    公开(公告)日：2012-12-18

    申请号：US12184386

    申请日：2008-08-01

    申请人： Stephen A. McCormick ,  Michael Newman ,  Robert Muscato

    发明人： Stephen A. McCormick ,  Michael Newman ,  Robert Muscato

    IPC分类号： F25D25/02 ,  F25D13/06

    CPC分类号： F25D13/067 ,  A21B1/26 ,  A21B1/48

    摘要： A heat transfer system for refrigeration and/or heating of products includes a housing having an internal chamber, a baffle, a spiral pathway around the baffle, a gas flow pathway and a blower to circulate gas along the gas flow pathway. The baffle separates the chamber into upper and lower portions. The spiral pathway includes an upper spiral pathway within the upper portion, and a lower spiral pathway within the lower portion. The gas flow pathway includes an upper gas flow pathway across the upper spiral pathway and a lower gas flow pathway across the lower spiral pathway in which gas flow in the upper and lower gas flow pathways defines a circulation loop. The width of the upper gas flow pathway and upper spiral pathway are similar, and the width of the lower gas flow pathway and lower spiral pathway are similar.

    摘要翻译： 用于制冷和/或加热产品的传热系统包括具有内室，挡板，围绕挡板的螺旋路径的壳体，气流通道和鼓风机，以沿气体流路循环气体。 挡板将腔室分成上部和下部。 螺旋通道包括在上部内的上螺旋通路，下部包括下螺旋通路。 气流通道包括穿过上螺旋通路的上气流通道和穿过下螺旋路径的下气流通道，其中上，下气流通道中的气流限定循环回路。 上部气体流路和上部螺旋路径的宽度相似，下部气体流路和下部螺旋路径的宽度相似。

    Drainback Solar Water Heater
    5.
    发明申请
    Drainback Solar Water Heater 审中-公开
    排水太阳能热水器

    公开(公告)号：US20110094498A1

    公开(公告)日：2011-04-28

    申请号：US12911135

    申请日：2010-10-25

    申请人： Michael Newman ,  Glen Newman

    发明人： Michael Newman ,  Glen Newman

    IPC分类号： F24J2/40 ,  F24J2/04

    CPC分类号： F24S50/00 ,  F24D11/003 ,  F24D2200/14 ,  F24S40/60 ,  Y02B10/20 ,  Y02E10/40

    摘要： A solar water heater includes a drainback unit with a drainback reservoir and an anti-airlock conduit for assuring that working fluid in the solar collectors is consistently drained from the solar collectors into a drainback reservoir once circulation the working fluid in the solar collectors has stopped. The drainback unit also provides rapid startup by positioning the heat exchanger outside of the drainback reservoir and by positioning the inlet and outlet of drainback reservoir in close proximity to each other.

    摘要翻译： 太阳能热水器包括具有排水储存器和防气锁导管的排水装置，用于确保太阳能收集器中的工作流体一旦从太阳能收集器排出到排水储存器中，一旦太阳能收集器中的工作流体循环停止。 排水装置还通过将热交换器定位在排水储存器的外部并且通过将排水储存器的入口和出口彼此靠近地定位来提供快速启动。

    System and method of microbiocidal gas generation
    8.
    发明申请
    System and method of microbiocidal gas generation 审中-公开
    微生物气体发生系统及方法

    公开(公告)号：US20050226817A1

    公开(公告)日：2005-10-13

    申请号：US11147025

    申请日：2005-06-07

    申请人： Michael Newman ,  Stephen McCormick

    发明人： Michael Newman ,  Stephen McCormick

    IPC分类号： A01N25/18 ,  A61L9/02 ,  A61K9/72

    CPC分类号： A01N25/18

    摘要： An apparatus and method of microbiocidal gas generation includes generating a microbiocidal agent, such as lactic acid, without the need for a carrier gas. A liquid microbiocidal agent is introduced into a heat exchanger where it is heated to generate a gaseous miocrobiocidal agent without a carrier gas for use with food products, while eliminating the costs, additional equipment and additional steps associated with the use of a carrier gas in the generation of microbiocidal agents.

    摘要翻译： 微生物气体发生的装置和方法包括生成杀微生物剂如乳酸，而不需要载气。 将液体杀微生物剂引入热交换器中，在其中将其加热以产生气体杀微生物剂，而没有用于食品的载体气体，同时消除与使用载体气体相关的成本，附加设备和附加步骤 生成杀微生物剂。

    Modification of film processor chemistry proportional heating during replenishment
    9.
    发明授权
    Modification of film processor chemistry proportional heating during replenishment 失效
    补充期间电影处理器化学成比例加热的修改

    公开(公告)号：US5235371A

    公开(公告)日：1993-08-10

    申请号：US759454

    申请日：1991-09-13

    申请人： James T. Samuels ,  Michael Newman

    发明人： James T. Samuels ,  Michael Newman

    IPC分类号： G03D3/00 ,  G03D3/08 ,  G03D3/13 ,  G03D13/00 ,  G03D15/02

    CPC分类号： G03D3/132 ,  G03D13/006 ,  G03D13/007

    摘要： A temperature control system (10) of an automatic film processor (12) includes developer and fixer recirculation paths (30, 40) having thermowell heaters (34, 44) and thermistors (35, 45). The heating rate of a heating cycle is determined based on temperature measurements by the thermistor (35). The duty cycle of heater (34) is controlled in proportion to the difference between measured actual temperature and a preestablished setpoint temperature. When replenishment occurs, until the cooler slug of replenishment becomes mixed, heater duty cycle is chosen based on prereplenishment temperature as well as measured temperature. In a modified embodiment, until the slug is mixed, a single predefined heater duty cycle is set.

    摘要翻译： 自动胶片处理器（12）的温度控制系统（10）包括具有热套管加热器（34,44）和热敏电阻（35,45）的显影剂和定影剂再循环路径（30,40）。 基于热敏电阻（35）的温度测定来确定加热循环的加热速度。 加热器（34）的占空比根据测量的实际温度和预先设定的设定点温度之间的差异进行控制。 当补货发生时，直到补充的冷却块混合，加热器占空比基于预先施加的温度和测量的温度来选择。 在一个修改的实施例中，直到块塞混合，设定单个预定加热器占空比。