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公开(公告)号：US20090202456A1
公开(公告)日：2009-08-13
申请号：US12058387
申请日：2008-03-28
申请人： Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
IPC分类号： A61K8/44 , A61K31/195 , A61Q11/00
CPC分类号： A61K8/44 , A61K8/463 , A61K8/55 , A61K8/8164 , A61K31/198 , A61Q11/00
摘要： The invention relates to novel arginine salts, compositions comprising them, and their uses.
摘要翻译： 本发明涉及新颖的精氨酸盐，包含它们的组合物及其用途。
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公开(公告)号：US09682026B2
公开(公告)日：2017-06-20
申请号：US12058360
申请日：2008-03-28
申请人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
IPC分类号： A61K8/00 , A61Q11/00 , A61K8/25 , A61K8/21 , A61K8/19 , A61K8/40 , A61K8/44 , A61K8/24 , A61K31/198
摘要： This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5; an effective amount of a soluble fluoride salt; and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
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公开(公告)号：US09682027B2
公开(公告)日：2017-06-20
申请号：US12058424
申请日：2008-03-28
申请人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
CPC分类号： A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
摘要： This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.
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公开(公告)号：US20090202454A1
公开(公告)日：2009-08-13
申请号：US12058209
申请日：2008-03-28
申请人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.
摘要翻译： 本发明涉及包含游离或盐形式的有效量的碱性氨基酸与抗菌剂的口腔护理组合物，以及使用和制备这些组合物的方法。
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公开(公告)号：US20090202451A1
公开(公告)日：2009-08-13
申请号：US12058424
申请日：2008-03-28
申请人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
CPC分类号： A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
摘要： This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.
摘要翻译： 本发明涉及包含碱性氨基酸或其盐和小颗粒级分的口腔护理组合物以及使用和制备这些组合物的方法。
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公开(公告)号：US11612553B2
公开(公告)日：2023-03-28
申请号：US12058209
申请日：2008-03-28
申请人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.
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公开(公告)号：US20090202452A1
公开(公告)日：2009-08-13
申请号：US12272257
申请日：2008-11-17
申请人： Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia, III , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia, III , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
CPC分类号： A61K8/25 , A61K8/44 , A61K2800/28 , A61K2800/412 , A61K2800/88 , A61Q11/00
摘要： The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.
摘要翻译： 本发明包括清洁口腔表面，维持口腔健康和/或增加口腔健康的方法。 这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触，使口腔表面与定期的口腔护理维持组合物每月至少一次接触，其中定期口腔护理维持组合物包含游离或 任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。 适用于该方法的定期口腔护理清洁组合物包括研磨系统。
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公开(公告)号：US20090202455A1
公开(公告)日：2009-08-13
申请号：US12058360
申请日：2008-03-28
申请人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
摘要： This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5; an effective amount of a soluble fluoride salt; and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
摘要翻译： 本发明涉及口腔护理组合物，其包含有效量的碱性氨基酸盐，该盐在无缓冲溶液中的pH值小于约7.5; 有效量的可溶性氟化物盐; 以及具有小于约7.5的无缓冲溶液中的pH的颗粒材料; 以及使用和制备这种组合物的方法。
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公开(公告)号：US20090202450A1
公开(公告)日：2009-08-13
申请号：US12058278
申请日：2008-03-28
申请人： Michael Prencipe , Diane Cummins , Ravi Subramanayam , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Donghui Wu , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Diane Cummins , Ravi Subramanayam , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Donghui Wu , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.
摘要翻译： 本发明涉及包含游离或盐形式的有效量的碱性氨基酸以及阴离子表面活性剂的口腔护理组合物，以及使用和制备这些组合物的方法。
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公开(公告)号：US20080274065A1
公开(公告)日：2008-11-06
申请号：US12028782
申请日：2008-02-08
申请人： Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
CPC分类号： A61K8/25 , A61K8/44 , A61K2800/28 , A61K2800/412 , A61K2800/88 , A61Q11/00
摘要： The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.
摘要翻译： 本发明包括清洁口腔表面，维持口腔健康和/或增加口腔健康的方法。 这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触，使口腔表面与定期的口腔护理维持组合物每月至少一次接触，其中定期口腔护理维持组合物包含游离或 任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。 适用于该方法的定期口腔护理清洁组合物包括研磨系统。
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