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公开(公告)号：US07893046B2
公开(公告)日：2011-02-22
申请号：US12305646
申请日：2007-06-19
申请人： Mie Kaino , Hiroyuki Meguro , Hiroe Hirokawa , Naoyoshi Yamamoto
发明人： Mie Kaino , Hiroyuki Meguro , Hiroe Hirokawa , Naoyoshi Yamamoto
CPC分类号： C07D239/34 , A61K31/351 , A61K31/357 , A61K31/505 , A61K31/506 , A61K31/513 , A61K31/515 , C07D239/42 , C07D239/60 , C07D309/10 , C07D313/04 , C07D401/12 , C07D405/12 , C07D417/12
摘要： A therapeutic or prophylactic agent for leukemia is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for leukemia according to the present invention shows the excellent absorbability and in vivo stability when orally administered, and exhibits prominent therapeutic or prophylactic effects.
摘要翻译： 公开了一种用于白血病的治疗或预防剂。 治疗或预防剂包括作为有效成分的具有特定结构的甘氨酸衍生物或其药学上可接受的盐，例如下述化合物[（E）-2-（2,6-二氯苯甲酰氨基）-5- [ 4-（异丙基 - 嘧啶-2-基氨基）苯基]戊-4-烯酸]。 本发明的白血病治疗剂或预防剂在口服给药时显示出优异的吸收性和体内稳定性，具有显着的治疗或预防效果。
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公开(公告)号：US20090253724A1
公开(公告)日：2009-10-08
申请号：US12305646
申请日：2007-06-19
申请人： Mie Kaino , Hiroyuki Meguro , Hiroe Hirokawa , Naoyoshi Yamamoto
发明人： Mie Kaino , Hiroyuki Meguro , Hiroe Hirokawa , Naoyoshi Yamamoto
IPC分类号： A61K31/505
CPC分类号： C07D239/34 , A61K31/351 , A61K31/357 , A61K31/505 , A61K31/506 , A61K31/513 , A61K31/515 , C07D239/42 , C07D239/60 , C07D309/10 , C07D313/04 , C07D401/12 , C07D405/12 , C07D417/12
摘要： A therapeutic or prophylactic agent for leukemia is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for leukemia according to the present invention shows the excellent absorbability and in vivo stability when orally administered, and exhibits prominent therapeutic or prophylactic effects.
摘要翻译： 公开了一种用于白血病的治疗或预防剂。 治疗或预防剂包括作为有效成分的具有特定结构的甘氨酸衍生物或其药学上可接受的盐，例如下述化合物[（E）-2-（2,6-二氯苯甲酰氨基）-5- [ 4-（异丙基 - 嘧啶-2-基氨基）苯基]戊-4-烯酸]。 本发明的白血病治疗剂或预防剂在口服给药时显示出优异的吸收性和体内稳定性，具有显着的治疗或预防效果。
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公开(公告)号：US20090093508A1
公开(公告)日：2009-04-09
申请号：US12304964
申请日：2007-06-14
申请人： Mie Kaino , Hiroyuki Meguro
发明人： Mie Kaino , Hiroyuki Meguro
IPC分类号： A61K31/501 , A61K31/351 , A61P17/02 , A61P29/00
CPC分类号： C07D239/42 , A61K31/335 , A61K31/351 , A61K31/505 , A61K31/506 , C07D239/34 , C07D239/47 , C07D239/52 , C07D239/60 , C07D309/06 , C07D309/10 , C07D313/04 , C07D401/12 , C07D405/12 , C07D417/12
摘要： A therapeutic or prophylactic agent for allergic dermatitis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for allergic dermatitis according to the present invention has high therapeutic or prophylactic effect.
摘要翻译： 公开了用于过敏性皮炎的治疗或预防剂。 治疗或预防剂包括作为有效成分的具有特定结构的甘氨酸衍生物或其药学上可接受的盐，例如下述化合物[（E）-2-（2,6-二氯苯甲酰氨基）-5- [ 4-（异丙基 - 嘧啶-2-基氨基）苯基]戊-4-烯酸]。 本发明的变态反应性皮炎的治疗或预防剂具有高的治疗或预防效果。
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公开(公告)号：US20090275599A1
公开(公告)日：2009-11-05
申请号：US12305078
申请日：2007-06-18
申请人： Kenichi Hayashi , Mie Kaino , Hiroyuki Meguro
发明人： Kenichi Hayashi , Mie Kaino , Hiroyuki Meguro
IPC分类号： A61K31/505 , C07D309/10 , A61K31/35 , C07D239/34 , C07D239/42 , C07D401/12
CPC分类号： C07D239/42 , A61K31/335 , A61K31/351 , A61K31/505 , A61K31/506 , C07C233/85 , C07D239/34 , C07D239/47 , C07D239/52 , C07D239/60 , C07D309/06 , C07D309/12 , C07D313/04 , C07D401/12 , C07D405/12 , C07D417/12
摘要： A therapeutic or prophylactic agent for multiple sclerosis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for multiple sclerosis according to the present invention shows the excellent absorbability and in vivo stability when orally administered, and exhibits high therapeutic or prophylactic effects.
摘要翻译： 公开了一种用于多发性硬化的治疗或预防剂。 治疗或预防剂包括作为有效成分的具有特定结构的甘氨酸衍生物或其药学上可接受的盐，例如下述化合物[（E）-2-（2,6-二氯苯甲酰氨基）-5- [ 4-（异丙基 - 嘧啶-2-基氨基）苯基]戊-4-烯酸]。 根据本发明的多发性硬化症的治疗或预防剂在口服给药时显示出优异的吸收性和体内稳定性，并表现出高度的治疗或预防效果。
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公开(公告)号：US07879837B2
公开(公告)日：2011-02-01
申请号：US12305078
申请日：2007-06-18
申请人： Kenichi Hayashi , Mie Kaino , Hiroyuki Meguro
发明人： Kenichi Hayashi , Mie Kaino , Hiroyuki Meguro
CPC分类号： C07D239/42 , A61K31/335 , A61K31/351 , A61K31/505 , A61K31/506 , C07C233/85 , C07D239/34 , C07D239/47 , C07D239/52 , C07D239/60 , C07D309/06 , C07D309/12 , C07D313/04 , C07D401/12 , C07D405/12 , C07D417/12
摘要： A therapeutic or prophylactic agent for multiple sclerosis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for multiple sclerosis according to the present invention shows the excellent absorbability and in vivo stability when orally administered, and exhibits high therapeutic or prophylactic effects.
摘要翻译： 公开了一种用于多发性硬化的治疗或预防剂。 治疗或预防剂包括作为有效成分的具有特定结构的甘氨酸衍生物或其药学上可接受的盐，例如下述化合物[（E）-2-（2,6-二氯苯甲酰氨基）-5- [ 4-（异丙基 - 嘧啶-2-基氨基）苯基]戊-4-烯酸]。 根据本发明的多发性硬化症的治疗或预防剂在口服给药时显示出优异的吸收性和体内稳定性，并表现出高度的治疗或预防效果。
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6.发明申请2,3-DIHYDRO-1H-INDENE-2-YL UREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME 有权2,3-二氢-1H-茚-2-基脲衍生物及其药物应用公开(公告)号：US20120184735A1
公开(公告)日：2012-07-19
申请号：US13497819
申请日：2010-09-30
申请人： Hiroaki Kaneko , Hideki Kawai , Yosuke Iura , Hideki Inoue , Mie Kaino , Hiroyuki Meguro , Tazuru Uchida
发明人： Hiroaki Kaneko , Hideki Kawai , Yosuke Iura , Hideki Inoue , Mie Kaino , Hiroyuki Meguro , Tazuru Uchida
IPC分类号： C07D223/04 , C07C275/34 , C07D207/09 , C07D309/06 , C07D295/12 , C07D211/06
CPC分类号： C07D309/06 , C07C275/34 , C07C275/40 , C07C275/42 , C07C2601/04 , C07C2602/08 , C07D295/135
摘要： A 2,3-dihydro-1H-indene-2-yl urea derivative represented by Formula (Ia) or a pharmaceutically acceptable salt thereof:
摘要翻译： 由式（Ia）表示的2,3-二氢-1H-茚-2-基脲衍生物或其药学上可接受的盐：
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7.发明授权2,3-dihydro-1H-indene-2-yl urea derivative and pharmaceutical application of same 有权2,3-二氢-1H-茚-2-基脲衍生物及其药物应用公开(公告)号：US08653304B2
公开(公告)日：2014-02-18
申请号：US13497819
申请日：2010-09-30
申请人： Hiroaki Kaneko , Hideki Kawai , Yosuke Iura , Hideki Inoue , Mie Kaino , Hiroyuki Meguro , Tazuru Uchida
发明人： Hiroaki Kaneko , Hideki Kawai , Yosuke Iura , Hideki Inoue , Mie Kaino , Hiroyuki Meguro , Tazuru Uchida
IPC分类号： C07C275/26 , C07C275/28 , A61K31/17
CPC分类号： C07D309/06 , C07C275/34 , C07C275/40 , C07C275/42 , C07C2601/04 , C07C2602/08 , C07D295/135
摘要： A 2,3-dihydro-1H-indene-2-yl urea represented by Formula (Ia) or a pharmaceutically acceptable salt thereof:
摘要翻译： 由式（Ia）表示的2,3-二氢-1H-茚-2-基脲或其药学上可接受的盐：
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公开(公告)号：US20130150390A1
公开(公告)日：2013-06-13
申请号：US13711783
申请日：2012-12-12
申请人： Mie Kaino , Hiroyuki Meguro
发明人： Mie Kaino , Hiroyuki Meguro
IPC分类号： C07D239/42 , C07D313/04 , C07D309/06 , C07D239/34 , C07D405/12 , C07D239/60 , C07D401/12 , C07D417/12 , C07D239/47 , C07D309/10 , C07D239/52
CPC分类号： C07D239/42 , A61K31/335 , A61K31/351 , A61K31/505 , A61K31/506 , C07D239/34 , C07D239/47 , C07D239/52 , C07D239/60 , C07D309/06 , C07D309/10 , C07D313/04 , C07D401/12 , C07D405/12 , C07D417/12
摘要： A therapeutic or prophylactic agent for allergic dermatitis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for allergic dermatitis according to the present invention has high therapeutic or prophylactic effect.
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公开(公告)号：US20130050659A1
公开(公告)日：2013-02-28
申请号：US13587295
申请日：2012-08-16
申请人： Satoru AWANE , Hiroyuki Meguro
发明人： Satoru AWANE , Hiroyuki Meguro
IPC分类号： G03B21/16
CPC分类号： G03B21/16 , G02B27/0006 , H04N9/3144
摘要： A projection display apparatus includes: a substantially box-shaped enclosure having a bottom surface portion, the bottom surface portion having an ventilation groove and an air inlet formed through a wall of the ventilation groove; an air sucking fan provided in the enclosure and forming an air flow flowing through the air inlet into the enclosure, and a filter through which the air flowing through the air inlet into the enclosure passes.
摘要翻译： 投影显示装置包括：具有底表面部分的基本上为箱形的外壳，底表面部分具有通风槽和通过通风槽的壁形成的空气入口; 设置在所述外壳中并形成流过所述空气入口到所述外壳中的空气流的空气吸入风扇，以及流过所述空气入口进入所述外壳的空气通过的过滤器。
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公开(公告)号：US07990708B2
公开(公告)日：2011-08-02
申请号：US12620644
申请日：2009-11-18
CPC分类号： G03B21/16
摘要： A blower for an electronic device includes a fan frame having an opening through which air passes for cooling the electronic device; a blade arranged in the opening of the fan frame; a motor configured to rotationally drive the blade; an attachment portion provided outside the opening of the fan frame, the attachment portion causing the fan frame to be attached to the electronic device; and a holder fixed to the electronic device and holding the attachment portion in a direction perpendicular to a rotational axis of the blade.
摘要翻译： 一种用于电子设备的鼓风机包括：风扇框架，具有空气通过的开口，用于冷却电子设备; 叶片，布置在风扇框架的开口中; 构造成旋转地驱动所述叶片的马达; 设置在所述风扇框架的开口的外侧的安装部，所述安装部使所述风扇框架附接到所述电子设备; 固定在电子设备上并且保持安装部分在垂直于叶片旋转轴线的方向上的保持架。
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