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公开(公告)号:US07947819B2
公开(公告)日:2011-05-24
申请号:US10873057
申请日:2004-06-21
IPC分类号: C07H21/04
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/178
摘要: The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumors of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in human subjects, and the development of anti-cancer therapeutics.
摘要翻译: 本发明涉及B-Raf基因产物中的突变。 所描述的突变在天然来源的人类肿瘤中鉴定。 这些突变与癌症表型相关,可用作诊断癌症,癌细胞或人类受试者癌症倾向的基础,以及抗癌治疗的发展。
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公开(公告)号:US08580497B2
公开(公告)日:2013-11-12
申请号:US12958951
申请日:2010-12-02
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/178
摘要: The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumors of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in human subjects, and the development of anti-cancer therapeutics.
摘要翻译: 本发明涉及B-Raf基因产物中的突变。 所描述的突变在天然来源的人类肿瘤中鉴定。 这些突变与癌症表型相关,可用作诊断癌症,癌细胞或人类受试者癌症倾向的基础,以及抗癌治疗的发展。
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公开(公告)号:US20110189688A1
公开(公告)日:2011-08-04
申请号:US12958951
申请日:2010-12-02
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/178
摘要: The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumours of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in human subjects, and the development of anti-cancer therapeutics.
摘要翻译: 本发明涉及B-Raf基因产物中的突变。 所描述的突变在天然来源的人类肿瘤中鉴定。 这些突变与癌症表型相关,可用作诊断癌症,癌细胞或人类受试者癌症倾向的基础,以及抗癌治疗的发展。
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公开(公告)号:US20050186584A1
公开(公告)日:2005-08-25
申请号:US10873057
申请日:2004-06-21
申请人: Mike Stratton , Andy Futreal , Richard Wooster , Richard Marais , Chris Marshall
发明人: Mike Stratton , Andy Futreal , Richard Wooster , Richard Marais , Chris Marshall
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/178
摘要: The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumours of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in human subjects, and the development of anti-cancer therapeutics.
摘要翻译: 本发明涉及B-Raf基因产物中的突变。 所描述的突变在天然来源的人类肿瘤中鉴定。 这些突变与癌症表型相关,可用作诊断癌症,癌细胞或人类受试者癌症倾向的基础,以及抗癌治疗的发展。
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