公开(公告)号：US08435449B2

公开(公告)日：2013-05-07

申请号：US12528388

申请日：2008-03-04

申请人： Mikihiro Yamanaka ,  Katsutoshi Takao ,  Tomohisa Kawata ,  Norie Matsui ,  Shuhji Nishiura ,  Keita Hara ,  Yasuaki Murashi ,  Jun Kudo

发明人： Mikihiro Yamanaka ,  Katsutoshi Takao ,  Tomohisa Kawata ,  Norie Matsui ,  Shuhji Nishiura ,  Keita Hara ,  Yasuaki Murashi ,  Jun Kudo

IPC分类号： G01N27/04

CPC分类号： G01N21/77 ,  G01N27/12 ,  G01N2021/7786

摘要： A chemical substance sensing element 142 for detecting a specific chemical substance included in biological information includes a carbon nanostructure and, because of metal complex or a fluorescent molecule modifying its surface, exhibits substance selectivity and high sensitivity. Of the substances modifying the surface of carbon nanostructures, CoPc reacts with NO and pentane and DAF-2 reacts with NO, as the components contained in the biological information, respectively, and both produce reaction products. The reaction product derived from CoPc changes electric resistance between nodes 154 and 156, and the reaction product derived from DAF-2 generates fluorescence of a specific wavelength when irradiated with excitation light. Therefore, by measuring the change in electric resistance or presence/absence and wavelength of fluorescent of the present element, sensing of NO or pentane is possible.

摘要翻译： 用于检测包括在生物信息中的特定化学物质的化学物质感测元件142包括碳纳米结构，并且由于金属络合物或改变其表面的荧光分子表现出物质选择性和高灵敏度。 在改变碳纳米结构表面的物质中，CoPc与NO和戊烷反应，DAF-2分别作为生物信息中所含的组分与NO反应，并产生反应产物。 衍生自CoPc的反应产物改变节点154和156之间的电阻，当用激发光照射时，衍生自DAF-2的反应产物产生特定波长的荧光。 因此，通过测量本元件的电阻变化或荧光的存在/不存在波长，可以检测NO或戊烷。

公开(公告)号：US20100086439A1

公开(公告)日：2010-04-08

申请号：US12528388

申请日：2008-03-04

申请人： Mikihiro Yamanaka ,  Katsutoshi Takao ,  Tomohisa Kawata ,  Norie Matsui ,  Shuhji Nishiura ,  Keita Hara ,  Yasuaki Murashi ,  Jun Kudo

发明人： Mikihiro Yamanaka ,  Katsutoshi Takao ,  Tomohisa Kawata ,  Norie Matsui ,  Shuhji Nishiura ,  Keita Hara ,  Yasuaki Murashi ,  Jun Kudo

IPC分类号： G01N21/76 ,  B01J19/00 ,  G01N21/64 ,  G01N27/04 ,  B05D3/14

CPC分类号： G01N21/77 ,  G01N27/12 ,  G01N2021/7786

摘要： A chemical substance sensing element 142 for detecting a specific chemical substance included in biological information includes a carbon nanostructure and, because of metal complex or a fluorescent molecule modifying its surface, exhibits substance selectivity and high sensitivity. Of the substances modifying the surface of carbon nanostructures, CoPc reacts with NO and pentane and DAF-2 reacts with NO, as the components contained in the biological information, respectively, and both produce reaction products. The reaction product derived from CoPc changes electric resistance between nodes 154 and 156, and the reaction product derived from DAF-2 generates fluorescence of a specific wavelength when irradiated with excitation light. Therefore, by measuring the change in electric resistance or presence/absence and wavelength of fluorescent of the present element, sensing of NO or pentane is possible.

摘要翻译： 用于检测包括在生物信息中的特定化学物质的化学物质感测元件142包括碳纳米结构，并且由于金属络合物或改变其表面的荧光分子表现出物质选择性和高灵敏度。 在改变碳纳米结构表面的物质中，CoPc与NO和戊烷反应，DAF-2分别作为生物信息中所含的组分与NO反应，并产生反应产物。 衍生自CoPc的反应产物改变节点154和156之间的电阻，当用激发光照射时，衍生自DAF-2的反应产物产生特定波长的荧光。 因此，通过测量本元件的电阻变化或荧光的存在/不存在波长，可以检测NO或戊烷。

公开(公告)号：US20120136584A1

公开(公告)日：2012-05-31

申请号：US13388934

申请日：2010-07-26

申请人： Kazuo Ban ,  Kazushi Fujioka ,  Norie Matsui ,  Shuhji Nishiura ,  Hiroki Okuno ,  Katsutoshi Takao

发明人： Kazuo Ban ,  Kazushi Fujioka ,  Norie Matsui ,  Shuhji Nishiura ,  Hiroki Okuno ,  Katsutoshi Takao

IPC分类号： G01N21/49 ,  G06F19/00

CPC分类号： G01N15/1459 ,  G01N15/1429 ,  G01N2015/1486 ,  G01N2015/1493

摘要： A light receiving element provides a current signal corresponding to an amount of received light scattered by suspended particles moving at a predetermined speed to a pulse width measurement circuit and a current-voltage conversion circuit via a filter circuit. A pulse width measured from the current signal is converted into a voltage value based on a predetermined relationship by a pulse width-voltage conversion circuit, and is provided to a voltage comparison circuit. The current-voltage conversion circuit converts a peak value of the current signal into a voltage value, and an amplifier circuit amplifies the signal at a predetermined amplification factor and provides the same to the voltage comparison circuit. The voltage comparison circuit uses the voltage value converted from the pulse width as a boundary value, and the suspended particles causing the scattered light are detected as microorganisms when the peak voltage value is smaller than the boundary value.

摘要翻译： 光接收元件提供与通过以预定速度移动的悬浮颗粒散射的接收光的量相对应的脉冲宽度测量电路和电流 - 电压转换电路的电流信号。 从电流信号测得的脉冲宽度由脉冲宽度 - 电压转换电路基于预定的关系转换为电压值，并提供给电压比较电路。 电流 - 电压转换电路将电流信号的峰值转换为电压值，并且放大器电路以预定的放大系数放大信号并将其提供给电压比较电路。 电压比较电路使用从脉冲宽度转换的电压值作为边界值，当峰值电压值小于边界值时，引起散射光的悬浮颗粒被检测为微生物。

公开(公告)号：US06828804B2

公开(公告)日：2004-12-07

申请号：US10726566

申请日：2003-12-04

申请人： Yuji Yashiro ,  Katsutoshi Takao

发明人： Yuji Yashiro ,  Katsutoshi Takao

IPC分类号： G01R2726

CPC分类号： G01Q30/16 ,  G01Q30/12 ,  G01Q60/48 ,  G01R27/2605 ,  Y10S977/854 ,  Y10S977/866

摘要： In the context of a measurement method in which scanning capacitance microscope(s) detecting surface(s) by means of electrically conductive probe(s) are used to measure electrical capacitance(s) of semiconductor sample surface(s), clean surface(s) are formed on semiconductor sample(s) by surface treatment; such semiconductor sample(s) are thereafter promptly placed in ultrahigh vacuum environment(s) (or inert gas environment(s)) and are maintained therein; and while still in this state, electrically conductive probe(s), on whose surface(s) stable insulating film(s) (e.g., vapor-deposited insulating diamond film(s)) are formed, are used to measure electrical capacitance(s) of semiconductor sample surface(s) while in ultrahigh vacuum environment(s) (or inert gas environment(s)).