公开(公告)号：US08097594B2

公开(公告)日：2012-01-17

申请号：US12379539

申请日：2009-02-24

申请人： Milind Dattatraya Sindkhedkar ,  Vijaya Narayan Desai ,  Rajesh Maganlal Loriya ,  Mahesh Vithalbhai Patel ,  Bharat Kalidas Trivedi ,  Rajesh Onkardas Bora ,  Santosh Devidas Diwakar ,  Ganesh Rajaram Jadhav ,  Shivaji Sampatrao Pawar

发明人： Milind Dattatraya Sindkhedkar ,  Vijaya Narayan Desai ,  Rajesh Maganlal Loriya ,  Mahesh Vithalbhai Patel ,  Bharat Kalidas Trivedi ,  Rajesh Onkardas Bora ,  Santosh Devidas Diwakar ,  Ganesh Rajaram Jadhav ,  Shivaji Sampatrao Pawar

IPC分类号： A61K31/70 ,  C07H17/08

CPC分类号： C07D493/04

摘要： The present invention provides compounds having antimicrobial activity for preventing and treating diseases caused by microbial infections. Thus, the present invention relates to novel semi-synthetic 11,12-γ lactone macrolides and ketolides having antimicrobial activity, processes for making compounds as well as pharmaceutical compositions containing said compounds as active ingredients and methods of treating microbial infections with the compounds.

摘要翻译： 本发明提供具有抗微生物活性的化合物，其用于预防和治疗由微生物感染引起的疾病。 因此，本发明涉及具有抗微生物活性的新型半合成11,12-γ内酯大环内酯和酮内酯，以及制备化合物的方法以及含有所述化合物作为活性成分的药物组合物以及用该化合物治疗微生物感染的方法。

公开(公告)号：US20090247478A1

公开(公告)日：2009-10-01

申请号：US12379539

申请日：2009-02-24

申请人： Milind Dattatraya Sindkhedkar ,  Vijaya Narayan Desai ,  Rajesh Maganlal Loriya ,  Mahesh Vithalbhai Patel ,  Bharat Kalidas Trivedi ,  Rajesh Onkardas Bora ,  Santosh Devidas Diwakar ,  Ganesh Rajaram Jadhav ,  Shivaji Sampatrao Pawar

发明人： Milind Dattatraya Sindkhedkar ,  Vijaya Narayan Desai ,  Rajesh Maganlal Loriya ,  Mahesh Vithalbhai Patel ,  Bharat Kalidas Trivedi ,  Rajesh Onkardas Bora ,  Santosh Devidas Diwakar ,  Ganesh Rajaram Jadhav ,  Shivaji Sampatrao Pawar

IPC分类号： A61K31/7048 ,  C07H17/08

CPC分类号： C07D493/04

摘要： The present invention provides compounds having antimicrobial activity for preventing and treating diseases caused by microbial infections. Thus, the present invention relates to novel semi-synthetic 11,12-γ lactone macrolides and ketolides having antimicrobial activity, processes for making compounds as well as pharmaceutical compositions containing said compounds as active ingredients and methods of treating microbial infections with the compounds.

摘要翻译： 本发明提供具有抗微生物活性的化合物，其用于预防和治疗由微生物感染引起的疾病。 因此，本发明涉及具有抗微生物活性的新型半合成的11,12-γ-内酯大环内酯和酮内酯，以及制备化合物的方法以及含有所述化合物作为活性成分的药物组合物以及用该化合物治疗微生物感染的方法。