公开(公告)号：US4009283A

公开(公告)日：1977-02-22

申请号：US655897

申请日：1976-02-06

申请人： Milton E. Herr ,  Roy A. Johnson

发明人： Milton E. Herr ,  Roy A. Johnson

IPC分类号： C07C205/45 ,  A61K31/19 ,  A61K31/235

CPC分类号： C07C205/45

摘要： In accordance with this invention, there are disclosed compounds of the formula ##STR1## wherein X is selected from the group consisting of nitro and amino with the proviso that when Y is hydrogen, X is nitro; Y is selected from the group consisting of hydrogen and fluoro; R is selected from the group consisting of hydrogen and alkyl of from one to six carbon atoms, inclusive.These compounds are compounded into pharmaceutical compositions and administered to mammals for purposes of relieving inflammation and to mammals in need of prophylactic anti-thrombotic treatment.

摘要翻译： 根据本发明，公开了下式的化合物，其中X选自硝基和氨基，条件是当Y是氢时，X是硝基; Y选自氢和氟; R选自氢和1-6个碳原子的烷基（包括端值）。

公开(公告)号：US3957861A

公开(公告)日：1976-05-18

申请号：US413647

申请日：1973-11-07

申请人： Milton E. Herr ,  Roy A. Johnson

发明人： Milton E. Herr ,  Roy A. Johnson

IPC分类号： C07C67/00 ,  C07C201/00 ,  C07C205/45 ,  C07C205/56 ,  C07C227/00 ,  C07C227/18 ,  C07C229/42 ,  C07D303/48 ,  C07C79/46 ,  C07C101/447

CPC分类号： C07C205/45 ,  C07C205/56 ,  C07D303/48 ,  Y10S514/822

摘要： In accordance with this invention, there are disclosed compounds of the formula ##SPC1##Wherein X is selected from the group consisting of nitro and amino with the proviso that when y is hydrogen, X is nitro; Y is selected from the group consisting of hydrogen and fluoro; R is selected from the group consisting of hydrogen and alkyl of from one to six carbon atoms, inclusive.These compounds are compounded into pharmaceutical compositions and administered to mammals for purposes of relieving inflammation and to mammals in need of prophylactic anti-thrombotic treatment.