公开(公告)号：US20130264221A1

公开(公告)日：2013-10-10

申请号：US13994348

申请日：2011-12-16

申请人： Min Gon Kim ,  Jun Hyoung Ahn ,  Yun Ju Sung ,  Yong Beom Shin ,  Hyo Arm Joung

发明人： Min Gon Kim ,  Jun Hyoung Ahn ,  Yun Ju Sung ,  Yong Beom Shin ,  Hyo Arm Joung

IPC分类号： G01N27/327 ,  A61B5/1486

CPC分类号： G01N27/3278 ,  A61B5/1486 ,  B82Y5/00 ,  B82Y15/00 ,  G01N27/3275 ,  G01N33/54346 ,  G01N33/54366

摘要： A membrane electrode includes a novel sensor combining a filtering function of a membrane and a signal measuring ability of an electrode. A target material may be measured by filtration through the membrane. A small amount of target materials may be detected with high sensitivity using an amplified electrical signal by increasing electrical conductivity by reducing metal ions on the membrane, and thus the target material may be subject to quantitative analysis. In addition, only a target material selectively binding to a receptor may be filtrated by passing a sample through the membrane after a receptor material is fixed to the electrode, and thus may be used to detect an electrical signal. In addition, the sensor may measure a signal in various methods such as electrical conductivity, impedance, etc.

摘要翻译： 膜电极包括结合膜的过滤功能和电极的信号测量能力的新型传感器。 目标材料可以通过膜过滤来测量。 使用放大的电信号，可以通过降低膜上的金属离子来提高导电性，可以以高灵敏度检测少量的目标材料，因此可以对靶材进行定量分析。 此外，只有选择性地结合受体的靶材料可以在将受体材料固定到电极之后通过样品通过膜来过滤，因此可以用于检测电信号。 此外，传感器可以以各种方法测量信号，例如导电性，阻抗等。

公开(公告)号：US09465003B2

公开(公告)日：2016-10-11

申请号：US13994348

申请日：2011-12-16

申请人： Min Gon Kim ,  Jun Hyoung Ahn ,  Yun Ju Sung ,  Yong Beom Shin ,  Hyo Arm Joung

发明人： Min Gon Kim ,  Jun Hyoung Ahn ,  Yun Ju Sung ,  Yong Beom Shin ,  Hyo Arm Joung

IPC分类号： G01N27/327 ,  G01N33/543 ,  A61B5/1486 ,  B82Y5/00 ,  B82Y15/00

CPC分类号： G01N27/3278 ,  A61B5/1486 ,  B82Y5/00 ,  B82Y15/00 ,  G01N27/3275 ,  G01N33/54346 ,  G01N33/54366

摘要： A membrane electrode includes a novel sensor combining a filtering function of a membrane and a signal measuring ability of an electrode. A target material may be measured by filtration through the membrane. A small amount of target materials may be detected with high sensitivity using an amplified electrical signal by increasing electrical conductivity by reducing metal ions on the membrane, and thus the target material may be subject to quantitative analysis. In addition, only a target material selectively binding to a receptor may be filtrated by passing a sample through the membrane after a receptor material is fixed to the electrode, and thus may be used to detect an electrical signal. In addition, the sensor may measure a signal in various methods such as electrical conductivity, impedance, etc.

摘要翻译： 膜电极包括结合膜的过滤功能和电极的信号测量能力的新型传感器。 目标材料可以通过膜过滤来测量。 使用放大的电信号，可以通过降低膜上的金属离子来提高导电性，可以以高灵敏度检测少量的目标材料，因此可以对靶材进行定量分析。 此外，只有选择性地结合受体的靶材料可以在将受体材料固定到电极之后通过样品通过膜来过滤，因此可以用于检测电信号。 此外，传感器可以以各种方法测量信号，例如导电性，阻抗等。

公开(公告)号：US09588111B2

公开(公告)日：2017-03-07

申请号：US13511962

申请日：2010-11-24

申请人： Min Gon Kim ,  Yong Beom Shin ,  Young Kyeng O ,  Hyo Arm Joung

发明人： Min Gon Kim ,  Yong Beom Shin ,  Young Kyeng O ,  Hyo Arm Joung

IPC分类号： C12M1/34 ,  G01N33/538 ,  G01N33/543

CPC分类号： G01N33/538 ,  G01N33/54366

摘要： The present invention relates to a membrane sensor having a multi-hole film attached thereto and a method for measuring immunological reactions or enzymatic reactions using the same. More specifically, the present invention relates to a membrane sensor in which a multi-hole film is joined to the top of a membrane on which receptors are immobilized, and a method for measuring immunological reactions or enzymatic reactions using the same. The present invention makes it possible to adjust the sensitivity of membrane biosensors by adjusting the hole size in the multi-hole film and so makes it possible to measure analytes with a high degree of sensitivity using just a small amount of sample, and makes it possible to simultaneously measure diverse types of analyte by attaching various types of receptor on the membrane sensor.

摘要翻译： 本发明涉及一种具有附着于其上的多孔膜的膜传感器，以及使用该膜传感器的免疫反应或酶反应的方法。 更具体地，本发明涉及一种膜传感器，其中多孔膜与固定有受体的膜的顶部接合，以及使用该膜传感器测量免疫反应或酶反应的方法。 本发明可以通过调整多孔膜中的孔尺寸来调节膜生物传感器的灵敏度，因此可以仅使用少量的样品来测量具有高灵敏度的分析物，并且使其成为可能 通过在膜传感器上附加各种类型的受体来同时测量不同类型的分析物。

公开(公告)号：US20120270235A1

公开(公告)日：2012-10-25

申请号：US13511962

申请日：2010-11-24

申请人： Min Gon Kim ,  Yong Beom Shin ,  Young Kyeng O ,  Hyo Arm Joung

发明人： Min Gon Kim ,  Yong Beom Shin ,  Young Kyeng O ,  Hyo Arm Joung

IPC分类号： G01N33/566 ,  G01N21/64 ,  G01N21/76 ,  G01N21/78 ,  B82Y15/00

CPC分类号： G01N33/538 ,  G01N33/54366

摘要： The present invention relates to a membrane sensor having a multi-hole film attached thereto and a method for measuring immunological reactions or enzymatic reactions using the same. More specifically, the present invention relates to a membrane sensor in which a multi-hole film is joined to the top of a membrane on which receptors are immobilized, and a method for measuring immunological reactions or enzymatic reactions using the same. The present invention makes it possible to adjust the sensitivity of membrane biosensors by adjusting the hole size in the multi-hole film and so makes it possible to measure analytes with a high degree of sensitivity using just a small amount of sample, and makes it possible to simultaneously measure diverse types of analyte by attaching various types of receptor on the membrane sensor.

摘要翻译： 本发明涉及一种具有附着于其上的多孔膜的膜传感器，以及使用该膜传感器的免疫反应或酶反应的方法。 更具体地，本发明涉及一种膜传感器，其中多孔膜与固定有受体的膜的顶部接合，以及使用该膜传感器测量免疫反应或酶反应的方法。 本发明可以通过调整多孔膜中的孔尺寸来调节膜生物传感器的灵敏度，因此可以仅使用少量的样品来测量具有高灵敏度的分析物，并且使其成为可能 通过在膜传感器上附加各种类型的受体来同时测量不同类型的分析物。