公开(公告)号：US20210378980A1

公开(公告)日：2021-12-09

申请号：US17277994

申请日：2019-09-20

Applicant: ModernaTX, Inc.

Inventor： Allen HORHOTA ,  Christopher Karl MCLAUGHLIN ,  Jessica CHENEY ,  Ben GELDHOF ,  Jeffrey HRKACH ,  Melissa J. MOORE ,  Stephen G. HOGE

IPC: A61K9/51 ,  A61K45/06

Abstract: The present disclosure provides methods of producing lipid nanoparticle (LNP) formulations and the produced LNP formulations thereof. The present disclosure also provides therapeutic and diagnostic uses related to the produced LNP formulations.

公开(公告)号：US20220062175A1

公开(公告)日：2022-03-03

申请号：US17424780

申请日：2020-01-31

Applicant: ModernaTX, Inc.

Inventor： Mike SMITH ,  Allen HORHOTA ,  Jason AUER ,  Brie SKINNER

IPC: A61K9/127 ,  A61K48/00 ,  A61K9/51

Abstract: The present disclosure provides methods of producing lipid nanoparticle (LNP) formulations and the produced LNP formulations thereof. The present disclosure also provides therapeutic and diagnostic uses related to the produced LNP formulations.