公开(公告)号：US20230285297A1

公开(公告)日：2023-09-14

申请号：US17792554

申请日：2021-01-29

Applicant: ModernaTX, Inc.

Inventor： Michael H. SMITH ,  Jason AUER ,  Brie SKINNER

IPC: A61K9/127 ,  A61K47/24 ,  A61K47/28 ,  A61K31/7105 ,  A61K47/26 ,  A61K47/12

CPC classification number: A61K9/1272 ,  A61K9/1271 ,  A61K9/1277 ,  A61K9/1278 ,  A61K31/7105 ,  A61K47/12 ,  A61K47/24 ,  A61K47/26 ,  A61K47/28

Abstract: The present disclosure provides methods of producing lipid nanoparticle (LNP) formulations and LNP formulations produced by using such methods. The present disclosure further provides therapeutic and diagnostic uses related to the produced LNP formulations.

公开(公告)号：US20230277457A1

公开(公告)日：2023-09-07

申请号：US18040745

申请日：2021-08-06

Applicant: ModernaTX, Inc.

Inventor： Richard Paul SHEPARD ,  Michael H. SMITH ,  Jason AUER ,  Brie SKINNER

IPC: A61K9/127 ,  A61K9/08

CPC classification number: A61K9/1277 ,  A61K9/1278 ,  A61K9/08 ,  A61K9/1271

Abstract: The present disclosure provides methods of producing lipid nanoparticle (LNP) formulations and the produced LNP formulations thereof. The present disclosure also provides therapeutic and diagnostic uses related to the produced LNP formulations.

公开(公告)号：US20220062175A1

公开(公告)日：2022-03-03

申请号：US17424780

申请日：2020-01-31

Applicant: ModernaTX, Inc.

Inventor： Mike SMITH ,  Allen HORHOTA ,  Jason AUER ,  Brie SKINNER

IPC: A61K9/127 ,  A61K48/00 ,  A61K9/51

Abstract: The present disclosure provides methods of producing lipid nanoparticle (LNP) formulations and the produced LNP formulations thereof. The present disclosure also provides therapeutic and diagnostic uses related to the produced LNP formulations.