专利检索 ap:("Monash University" OR "The Florey Institute of Neuroscience AND Mental Health" OR "St. Vincent's Institute of Medical Research") AND inv:"Michael W. PARKER" 第 1 页

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发明申请
4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors 审中-公开

公开(公告)号：US20180170891A1

公开(公告)日：2018-06-21

申请号：US15572554

申请日：2016-05-06

申请人： Monash University , The Florey Institute of Neuroscience and Mental Health , St. Vincent's Institute of Medical Research

发明人： Siew Yeen CHAI , Philip THOMPSON , Simon MOUNTFORD , Michael W. PARKER

IPC分类号： C07D309/32 , A61P25/28 , C07D405/10 , C07D405/04 , C07D409/10

CPC分类号： C07D309/32 , A61P25/28 , C07D405/04 , C07D405/10 , C07D407/10 , C07D409/10 , C07D493/04

摘要： The present disclosure relates generally, but not exclusively, to compounds and their use in therapy, to compositions and agents comprising said compounds, to methods of treatment using said compounds, and their use in the manufacture of medicaments. The disclosure further relates to inhibitors of IRAP and their use in the treatment or prevention of Alzheimer's disease and the treatment and prevention of memory and cognitive disorders.