公开(公告)号：US20220220160A1

公开(公告)日：2022-07-14

申请号：US17561332

申请日：2021-12-23

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Todd A. Ciche ,  Arlene R. Howe ,  Stephanie C. Waldheuser ,  Kimberly M. Wegener

IPC: C07K14/325 ,  A01N63/50 ,  A01P7/04 ,  C12N15/82

Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC13085 and TIC13087. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC13085 and TIC13087 pesticidal proteins are also provided.

公开(公告)号：US20230301308A1

公开(公告)日：2023-09-28

申请号：US18176410

申请日：2023-02-28

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Jason S. Milligan ,  Christina M. Taylor ,  Monika R. VanGordon ,  Kimberly M. Wegener ,  Brian E. Weiner

IPC: A01N63/50 ,  C12N15/82 ,  C12Q1/6895 ,  C07K14/32 ,  A01P7/04 ,  G01N33/68

CPC classification number: A01N63/50 ,  C12N15/8286 ,  C12Q1/6895 ,  C07K14/32 ,  A01P7/04 ,  G01N33/68 ,  C12Q2600/13

Abstract: Pesticidal proteins exhibiting inhibitory, suppressive, and toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4064 and TIC4064 amino acid sequence variants. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4064 and TIC4064 amino acid sequence variant pesticidal proteins are also provided.

公开(公告)号：US11744250B2

公开(公告)日：2023-09-05

申请号：US17559857

申请日：2021-12-22

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Jason S. Milligan ,  Christina M. Taylor ,  Monika R. VanGordon ,  Kimberly M. Wegener ,  Brian E. Weiner

IPC: A01N63/50 ,  A01P7/04 ,  C07K14/32 ,  C12N15/82 ,  C12Q1/6895 ,  G01N33/68

CPC classification number: A01N63/50 ,  A01P7/04 ,  C07K14/32 ,  C12N15/8286 ,  C12Q1/6895 ,  G01N33/68 ,  C12Q2600/13

Abstract: Pesticidal proteins exhibiting inhibitory, suppressive, and toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4064 and TIC4064 amino acid sequence variants. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4064 and TIC4064 amino acid sequence variant pesticidal proteins are also provided.

公开(公告)号：US11673922B2

公开(公告)日：2023-06-13

申请号：US17561332

申请日：2021-12-23

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Todd A. Ciche ,  Arlene R. Howe ,  Stephanie C. Waldheuser ,  Kimberly M. Wegener

IPC: C07K14/32 ,  C12N15/82 ,  A01P7/04 ,  A01N63/50 ,  C07K14/325

CPC classification number: C07K14/325 ,  A01N63/50 ,  A01P7/04 ,  C12N15/8286

Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC13085 and TIC13087. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC13085 and TIC13087 pesticidal proteins are also provided.

公开(公告)号：US20240425872A1

公开(公告)日：2024-12-26

申请号：US18793457

申请日：2024-08-02

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Kimberly M. Wegener

IPC: C12N15/82 ,  A01N63/23 ,  A01N63/50 ,  A01P7/04 ,  C07K14/32

Abstract: Pesticidal protein exhibiting toxic activity against Lepidopteran and Hemipteran pest species are disclosed, and include, but are not limited to, TIC2199. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the disclosed pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Lepidopteran and Hemipteran species pests using TIC2199 pesticidal protein are also provided.

公开(公告)号：US20220192200A1

公开(公告)日：2022-06-23

申请号：US17559857

申请日：2021-12-22

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Jason S. Milligan ,  Christina M. Taylor ,  Monika R. VanGordon ,  Kimberly M. Wegener ,  Brian E. Weiner

IPC: A01N63/50 ,  C12N15/82 ,  C12Q1/6895 ,  G01N33/68 ,  C07K14/32 ,  A01P7/04

Abstract: Pesticidal proteins exhibiting inhibitory, suppressive, and toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4064 and TIC4064 amino acid sequence variants. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4064 and TIC4064 amino acid sequence variant pesticidal proteins are also provided.