公开(公告)号：US12188028B1

公开(公告)日：2025-01-07

申请号：US15408402

申请日：2017-01-17

Applicant: MONSANTO TECHNOLOGY, LLC

Inventor： Ian W. Davis ,  Tedd D. Elich

IPC: C12N15/82

Abstract: The present invention provides methods, computer systems and computer-implemented products for making synthetic regulatory elements, and provides polynucleotide's, transgenic cells, and transgenic organisms (including viruses and viral vectors) produced by these methods. The invention thereby provides regulatory sequences to meet various gene expression objectives, including the ability to stack a plurality of heterologous genes for expression in a single cell, while avoiding gene silencing or reduced expression levels.

公开(公告)号：US11932862B1

公开(公告)日：2024-03-19

申请号：US17165734

申请日：2021-02-02

Applicant: Monsanto Technology LLC

Inventor： Ian W. Davis ,  Tedd D. Elich

IPC: C12N15/82

CPC classification number: C12N15/8216

Abstract: Polynucleotides comprising genetic regulatory elements, as well as constructs, host cells, and transgenic organisms comprising the same are described. The polynucleotides can control the expression of an operably linked gene in a host cell or organism, such as a plant cell or a plant. Methods of using the polynucleotide to control the expression of an operably linked gene of interest in a plant or plant cell are further provided.

公开(公告)号：US10030248B2

公开(公告)日：2018-07-24

申请号：US15174401

申请日：2016-06-06

Applicant: Monsanto Technology LLC

Inventor： Tedd D. Elich ,  Philip N. Benfey ,  Jee W. Jung

IPC: C12N15/113 ,  C12N15/82 ,  C12N15/63 ,  C07H21/00 ,  A01H1/04 ,  C12Q1/6895

Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.

公开(公告)号：US20170009248A1

公开(公告)日：2017-01-12

申请号：US15174401

申请日：2016-06-06

Applicant: Monsanto Technology LLC

Inventor： Tedd D. Elich ,  Philip N. Benfey ,  Jee W. Jung

IPC: C12N15/82 ,  C12Q1/68 ,  A01H1/04

CPC classification number: C12N15/8222 ,  A01H1/04 ,  C07H21/00 ,  C12N15/113 ,  C12N15/63 ,  C12N15/82 ,  C12N15/8201 ,  C12N15/8205 ,  C12N15/8216 ,  C12N15/8241 ,  C12N15/8261 ,  C12N15/8274 ,  C12N15/8286 ,  C12Q1/6895 ,  C12Q2600/158

Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.

Abstract translation: 本公开提供了用于调节植物细胞，植物组织和植物中可转录多核苷酸表达的组合物和方法。 组合物包括能够在植物组织和植物中提供表达的调节性多核苷酸分子。 还提供了使用本文公开的调节性多核苷酸分子在植物细胞，植物组织或植物中表达多核苷酸的方法。

公开(公告)号：US20140331358A1

公开(公告)日：2014-11-06

申请号：US14248663

申请日：2014-04-09

Applicant: Monsanto Technology LLC

Inventor： Tedd D. Elich ,  Philip N. Benfey ,  Ai-Jiuan Wu ,  David A. Orlando ,  Ian Davis

IPC: C12N15/82

CPC classification number: C12N15/8216 ,  C12N2830/65

Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.

公开(公告)号：US20150033407A1

公开(公告)日：2015-01-29

申请号：US14318440

申请日：2014-06-27

Applicant: Monsanto Technology LLC

Inventor： Tedd D. Elich ,  Philip N. Benfey ,  Ai-Jiuan Wu ,  David A. Orlando ,  Ian Davis

IPC: C12N15/82

CPC classification number: C12N15/8216 ,  C12N2830/65

Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.

Abstract translation: 本公开提供了用于调节植物细胞，植物组织和植物中可转录多核苷酸表达的组合物和方法。 组合物包括能够在植物组织和植物中提供表达的调节性多核苷酸分子。 还提供了使用本文公开的调节性多核苷酸分子在植物细胞，植物组织或植物中表达多核苷酸的方法。

公开(公告)号：US20140230093A1

公开(公告)日：2014-08-14

申请号：US14232895

申请日：2012-07-18

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Tedd D. Elich ,  Philip N. Benfey ,  Ian Davis ,  David A. Orlando

IPC: C12N15/82

CPC classification number: C12N15/8241 ,  C07K14/415 ,  C12N15/8227

Abstract: The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided.